Clinical trials: Vitamin C
Gastric Cancer
IV Ascorbic Acid in Advanced Gastric Cancer
Linus Pauling and Dr Ewan Cameron have published two retrospective studies about using high dose vitamin C to treat cancer patients forty years ago.
- Trial name
- NCT03015675
- Testing
- ascorbic acid, mFOLFOX6
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Type 2 Diabetes
The Effect of Lysulin on Glycemic Control and Advanced Glycation
The primary objective is to determine whether 12 weeks of treatment with Lysulin, compared to placebo, causes a reduction from baseline in the plasma levels of glucose, hemoglobin A1c (HbA1c) and Advanced Glycation Endproducts…
- Trial name
- NCT04234581
- Testing
- Lysulin
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Juraj Koska
Heart Failure With Normal Ejection Fraction
Treatment of HFpEF With Nitrate Supplement
The objective of this project is to determine if Neo40, a nitric oxide generating lozenge, when consumed twice daily by subjects with HFpEF, will increase exercise tolerance, decrease symptoms and improve quality of life for…
- Trial name
- NCT03289481
- Testing
- Active lozenge
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- MaineHealth
Dietary Supplements, Connective Tissue
Developing a Nutritional Supplement to Increase Collagen Synthesis in People
The purpose of this study is to test whether a natural product supplement can potentiate the increase in collagen synthesis following the ingestion of collagen protein.
- Conditions
- Dietary Supplements, Connective Tissue, Exercise
- Trial name
- NCT06138106
- Testing
- Natural Product Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Parkinson Disease, Healthy Adult Participants
Brain Dopamine Biomarker
This study is being conducted at the Morsani College of Medicine to determine whether signals recorded from the eyes and brain can be used as a noninvasive way to monitor dopamine function.
- Trial name
- B3-4D (NCT07748715)
- Testing
- Levadopa/Carbidopa eyedrops, Levodopa/Carbidopa (Sinemet)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Moderate Acute Malnutrition
Treating Moderate Malnutrition in 6-24 Months Old Children
Child malnutrition is intimately associated to poverty and may be due to sub-optimal feeding behaviours, food insecurity at household level, or a combination of both.
- Trial name
- LUCOMA (NCT01115647)
- Testing
- Ready-to-Use Therapeutic Food (RUTF), CBS++, CCC
- Where
- Burkina Faso
- Volunteers
- 2,088 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Anemia, Iron-Deficiency
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- FeGOS (NCT02666417)
- Testing
- Fortified maize porridge (MNP+iron), Fortified maize porridge (MNP+iron+GOS)
- Where
- Kenya
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Acne Vulgaris
Acne Treatment With Active Patches Which Contains Azelaic Acid, Citric Acid,Salicylic Acid and 2% Ascorbic Acid
The purpose of this study was to demonstrate the effect of short treatment with active OPLON patches on Acne.
- Trial name
- NCT01179633
- Testing
- OPLON active patch
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Oplon-Pure Science Ltd.
Basal Cell Carcinoma
Topical Vitamin C for Treatment of Basal Cell Cancer
Randomized coomparative trial of a 30% solution of ascorbic acid in 95% dimethylsulfoxide applied topically twice a day for 8 weeks vs 5% imiquimod cream in the treatment biopsy proven basal cell carcinomas inotherwise healthy…
- Trial name
- NCT04279535
- Testing
- Topical Ascorbic Acid
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Center for Biomedical Research, Inc.
Tuberculosis
Effect of Multivitamin Supplements on Clinical and Immunological Response in Childhood Tuberculosis
The purpose of this study is to see whether children who take vitamins along with the standard medicine for tuberculosis (TB) recover better and quicker than children who take only the standard medicine for TB.
- Trial name
- NCT00145184
- Testing
- Multivitamin supplement containing vitamins B, C, and E
- Where
- Tanzania
- Volunteers
- 40 people
- Sponsor
- Harvard School of Public Health (HSPH)
Metastatic Pancreatic Cancer, Pancreatic Cancer
High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
The purpose of this study is to see if a combination of paclitaxel protein bound (also known as nab-paclitaxel), gemcitabine, and cisplatin when given with high dose Ascorbic Acid will be safe and effective in individuals with…
- Conditions
- Metastatic Pancreatic Cancer, Pancreatic Cancer, Pancreas Cancer, Pancreatic Adenocarcinoma Resectable
- Trial name
- NCT03908333
- Testing
- Ascorbic Acid, Paclitaxel protein-bound, Cisplatin
- Where
- 6 sites in United States
- Sponsor
- Medical College of Wisconsin
Anemia of Pregnancy, Iron Deficiency Anemia
Liposomal Iron 30 mg Supplement in Non-anemic Pregnant Females
Protocol Summary: Liposomal Iron Supplementation in Non-anemic Pregnant Females This observational study aims to evaluate the efficacy and safety of daily liposomal iron supplementation (30 mg) in non-anemic pregnant women during…
- Trial name
- LITSNPF (NCT06669052)
- Testing
- 30 mg liposomal iron, capsules
- Volunteers
- 714 people, healthy volunteers welcome
- Sponsor
- Orchidia pharmaceutical Industries
Gingival Pigmentation
Microneedling With Vitamin C Versus Injectable Vitamin C for Depigmentation in Gingival Melanin Hyperpigmentation
The study is a randomized controlled clinical trial comparing the use of microneedling with vitamin C against injecting vitamin C for depigmentation in physiological gingival melanin hyperpigmentation in a group of patients…
- Trial name
- NCT05786885
- Testing
- Microneedling will be done with application of topical vitamin C paste for depigmentation, Vitamin C injection
- Volunteers
- 22 people
- Sponsor
- Cairo University
Stress, Stress (Psychology)
Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
This randomized controlled trial aims to evaluate the effect of a 4-week daily consumption of a functional date bar enriched with magnesium, vitamin C, and grape seed extract on perceived stress and salivary cortisol levels in…
- Trial name
- NCT07585422
- Testing
- Functional Bar
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- K.G. Razumovsky Moscow State University of Technologies and Management
Metastatic Pancreatic Cancer, Pancreatic Cancer
High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
The purpose of this study is to see if a combination of paclitaxel protein bound (also known as nab-paclitaxel), gemcitabine, and cisplatin when given with high dose Ascorbic Acid will be safe and effective in individuals with…
- Conditions
- Metastatic Pancreatic Cancer, Pancreatic Cancer, Pancreas Cancer, Pancreatic Adenocarcinoma Resectable
- Trial name
- NCT03697239
- Testing
- Ascorbic Acid, Paclitaxel protein-bound, Cisplatin
- Where
- United States
- Sponsor
- Hitendra Patel
Colonoscopy, Colon Polyp
The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation
Background 2L polyethylene glycol plus ascorbic acid (PEGA) is known to be as effective as standard 4L polyethylene glycol for bowel preparation. However, the volume of this regimen is still large.
- Conditions
- Colonoscopy, Colon Polyp, Bowel Preparation Solutions
- Trial name
- NCT03329339
- Testing
- 1 L PEG with ascorbic acid with prepackaged, low residue diet
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
Iron-deficiency, Ferritin Threshold
Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption
The serum or plasma ferritin concentration (referred to hereafter as ferritin) is the most widely used indicator to detect iron deficiency and a low ferritin indicates depleted iron stores.
- Conditions
- Iron-deficiency, Ferritin Threshold, Iron Absorption, Stable Iron Isotopes
- Trial name
- NCT05266703
- Testing
- Isotopically labelled iron sulfate 15mg
- Where
- Kenya
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Cholera, Diarrhea
Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants
The purpose of this study is to confirm the safety and immunogenicity of Peru-15 vaccine in infants when given simultaneously with measles vaccine.
- Conditions
- Cholera, Diarrhea, Vibrio Infections
- Trial name
- NCT00624975
- Testing
- Peru-15 Vaccine
- Where
- 2 sites in Bangladesh, India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Hip Fractures, Malnutrition
Impact of a Nutritional Supplement on the Recovery of the Nutritional Status of Patients With Spontaneous Hip Fracture
Multicenter, prospective, randomized, double-blind, interventional study with a nutritional supplement against placebo in a cohort of patients hospitalized for hip fracture.
- Trial name
- IRENE (NCT04183075)
- Testing
- FontActiv Superprotein/Hypercaloric Fiber, Carbohydrates and C Vitamin
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- Laboratorios Ordesa
Myeloma Multiple, Lymphoma
Effect of Vitamin C in Autologous Stem Cell Transplantations
In the study the investigators will randomize patients that receive an autologous stem cell transplantation for myeloma or lymphoma for treatment with vitamin C or placebo during 6 weeks. Primary endpoint will be immune recovery.
- Trial name
- VICAST (NCT03964688)
- Testing
- Vitamin C
- Where
- Netherlands
- Volunteers
- 47 people
- Sponsor
- Maastricht University Medical Center
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