Clinical trials: Vitamin C
Basal Cell Carcinoma
Topical Vitamin C for Treatment of Basal Cell Cancer
Randomized coomparative trial of a 30% solution of ascorbic acid in 95% dimethylsulfoxide applied topically twice a day for 8 weeks vs 5% imiquimod cream in the treatment biopsy proven basal cell carcinomas inotherwise healthy…
- Trial name
- NCT04279535
- Testing
- Topical Ascorbic Acid
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Center for Biomedical Research, Inc.
Vitamin D Deficiency
The D-BIICEP Study
Athletes and active individuals have been identified as an at-risk group for a low vitamin D status, specifically those residing in countries of higher latitude (such as the United Kingdom).
- Trial name
- D-BIICEP (NCT03253055)
- Testing
- DEXA, pQCT, Lifestyle Questionnaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Iron Deficiency Anemia
Acupoint TENS vs Resistance Training for Iron Deficiency Anemia
The current study is designed to compare between the effect of transcutaneous electrical acupoint stimulation and resistance exercises on hemoglobin level in women with iron deficiency anemia.The design of this study will be a…
- Trial name
- NCT07605676
- Testing
- Acupuncture transcutaneous electrical nerve stimulation (Acu-TENS), Resistance exercise training, Ferrous Sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Traumatic Brain Injury (TBI) Patients, Neuroinflammation
Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)
This study is a Phase II, randomized, quadruple-blinded, placebo-controlled clinical trial designed to test whether vitamin D₃ supplementation can improve recovery after mild-to-moderate traumatic brain injury (TBI) in adults.
- Trial name
- VIMOT (NCT07269457)
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- Nigeria
- Volunteers
- 240 people
- Sponsor
- Lagos State University
Iron Deficiency Anemia
Nutrient Fortified Oat Drink
This study will follow a randomized, double-blind, placebo-controlled, parallel-group design to test if an oat beverage fortified with iron, zinc vitamin A and vitamin C will improve nutrient status and iron deficiency in young…
- Trial name
- NCT01418898
- Testing
- Dietary Intervention
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Dermis Density, Wrinkles
The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Skin
The aim of the study is to compare the effects of multiple-dose 16 weeks daily dietary supplementation with 5 g or 3 g of collagen in combination with 1 g or 1.5 g of MSM and 80 mg vitamin C (see 1.2.
- Conditions
- Dermis Density, Wrinkles, Dermis Thickness, Skin Texture
- Trial name
- TO-COSKIN3 (NCT06755892)
- Testing
- ColMSM-HL, ColMSM-LH, ColMSM-LL
- Where
- Slovenia
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Nutrient Deficiency, Happiness
Alii Supplement Study
The goal of this clinical trial is to learn if the Alii Supplement can be used to reduce symptoms related to nutritional depletion in hormonal birth control pill users.
- Conditions
- Nutrient Deficiency, Happiness, Digestive Health, Vulnerability to Disease
- Trial name
- NCT07271316
- Testing
- Alii Supplement
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Texas Christian University
Glaucoma, Open-Angle
Citicoline & Antioxidants in Glaucoma
To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and…
- Trial name
- NCT06355765
- Testing
- Citicoline blackcurrant supplement
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Naples
Iron Deficiency Anemia Treatment, Iron Deficiency Anemia (IDA)
Treadmill Aerobic Training and Quality of Life in Anemic Females
This randomized controlled trial investigates the effects of an 8-week structured treadmill aerobic training program on physical fitness and health-related quality of life in young adult females diagnosed with mild-to-moderate…
- Trial name
- ATT-QoL-IDA (NCT07651098)
- Testing
- Treadmill Aerobic Exercise, Standard Medical Care and Nutritional Protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Colonoscopy
Different Bowel Preparations for Colonoscopy In Children
THE AIM OF THIS STUDY IS TO COMPARE THE EFFICACY, TOLERABILITY, AND SAFETY OF DIFFERENT BOWEL PREPARATIONS FOR COLONOSCOPY IN CHILDREN. THE AIM OF THIS STUDY IS TO COMPARE THE OVERALL COLON CLEANSING
- Trial name
- NCT01711437
- Testing
- PEG-4000 with citrates and simethicone, polyethylene glycol 4000 solution with simethicon, polyethylene glycol 3350 hyper-osmotic solution with ascorbic acid
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Policlinico Umberto I
Intestinal Barrier Function
The Effect of Probiotic Intake on Intestinal Permeability in Healthy Adults
In this double blind, crossover study participants will take a placebo for 3 weeks each. Gut permeability will be assessed weekly using food-grade sugar molecules.
- Trial name
- PIP (NCT03611400)
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Florida
Menopause, Vitamin D Deficiency
Effect of Consumption of Yogurt Fortified in Calcium and Vit. D on Circulating Levels of 25OHD in Postmenopausal Women
The purpose of this study is to evaluate the effect of daily consumption of one or two CALIN+ pot(s) versus no intake of product, after 4, 8, 12 and 16 weeks, on the evolution of the serum concentration of 25-hydroxy vitamin D…
- Trial name
- NCT02534064
- Testing
- CALIN+
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Yoplait France SAS
Glioblastoma, Glioblastoma Multiforme
A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma
This clinical trial evaluates adding ferumoxytol and pharamcologic ascorbate (vitamin C) to standard of care treatment of glioblastoma multiforme (a type of brain tumor) in adults.
- Trial name
- XACT-Fe-GBM-01 (NCT04900792)
- Testing
- Ferumoxytol injection, Pharmacological ascorbate, External beam radiation therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Bryan Allen
Vitamin C Deficiency, Acute Disease
A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency
The aim of this long-term observational study is the documentation of the use of PASCORBIN® 7.5 g in patients with vitamin C deficiency.
- Conditions
- Vitamin C Deficiency, Acute Disease, Chronic Disease
- Trial name
- NCT02422901
- Testing
- vitamin C
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
COVID-19
Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19
COVID-19 pandemic threatens patients, societies and healthcare systems around the world. The host immunity determines the progress of the disease and its lethality.
- Trial name
- ONSCOVID19 (NCT04323228)
- Testing
- Oral supplement enriched in antioxidants
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Saud University
Attention Deficit Hyperactivity Disorder
Combination Natural Health Product in Children With Attention Deficit/Hyperactivity Disorder (ADHD)
Attention deficit/hyperactivity disorder (ADHD) is a chronic neurobehavioural disorder often diagnosed in childhood years. Complementary/alternative treatments including natural health products (NHPs) are used by children with…
- Trial name
- NCT00704990
- Testing
- Zinc, Magnesium, Vitamin B6, Vitamin C (Compound Natural Health Product for ADHD)
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Kieran Cooley
Tissue Damage
High Doses Vitamin C and Tissular Repair in Surgical Patients
This is a prospective, randomize, double-blind, and placebo-controlled study to evaluate in patients with clinical criteria for any of the following open surgical procedure: (1) cesarean section; (2) aesthetic surgery like…
- Trial name
- NCT04896359
- Testing
- Vitamin C
- Where
- Ecuador
- Volunteers
- 80 people
- Sponsor
- Universidad San Francisco de Quito
Pregnancy
Maternal Vitamin D for Infant Growth (MDIG) Trial
The primary aims of this study are: 1) to determine whether maternal prenatal vitamin D3 supplementation (4200 IU/week, 16,800 IU/week, or 28,000 IU/week) versus placebo increases or decreases infant length at 1 year of age, and…
- Trial name
- MDIG (NCT01924013)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Bangladesh
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Heart Failure With Reduced Ejection Fraction
Exercise and NO in HFrEF
Heart disease is the leading cause of death in the United States, accounting for one in every four deaths in 2010 and costing over $300 billion annually in health care, medication, and lost productivity.
- Trial name
- NCT03136029
- Testing
- Antioxidant, Tetrahydrobiopterin (BH4), Exercise training
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- VA Office of Research and Development
Skin Cancer
The Effect of Green Tea and Vitamin C on Skin Health
There is little information on the effect of oral bioactive compounds on human skin clinically despite evidence of a beneficial effect from laboratory studies.
- Trial name
- NCT01032031
- Testing
- Green tea + vitamin C high dose
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Manchester
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