Clinical trials: Vitamin C
Multiple Myeloma and Plasma Cell Neoplasm
Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia
RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00258245
- Testing
- ascorbic acid, arsenic trioxide, bortezomib
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Premature Ovarian Failure (POF)
Autologous Bone Marrow Stem Cell Ovarian Transplantation to Restore Ovarian Function in Premature Ovarian Failure
This study aims to recover ovarian function in POF/POI patients. With this pueprose we designed a study protocol including two arms: ASCOT arm, were patients receive the stem cell mobilization treatment with Granulocyte colony…
- Trial name
- ASCOT-2 (NCT03535480)
- Testing
- G-CSF, ASCOT
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Malaria, Malaria in Pregnancy
Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component
Our objective was to investigate the importance of malaria infection/disease during pregnancy and more particularly during the first trimester; we also looked at the maternal-foetal interactions and their influence on the…
- Trial name
- NCT00680732
- Testing
- Multiple micronutrients supplements (MMS), Iron and folic acid (IFA), Chloroquine (CQ)
- Where
- Burkina Faso
- Volunteers
- 1,370 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Selective Eating, Emotional Dysregulation
Unflavored Powdered Multivitamin in Children
The goal of this clinical trial is to learn whether a daily unflavored powdered multivitamin (EllaOla Kids Essentials) improves mood and behavior in children aged 4 to 11 who are picky eaters and experience behavioral challenges.
- Conditions
- Selective Eating, Emotional Dysregulation, Child Behavior, Healthy Children (Wellness Study)
- Trial name
- BLOSSOM (NCT07863050)
- Testing
- EllaOla Kids Essentials Unflavored Powdered Multivitamin
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- EllaOla
Colon Cancer, Colon Disease
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia
A retrospective study to evaluate the effectiveness and safety of 1L polyethylene glycol (PEG)+ Ascorbic acid given for bowel preparation before colonoscopy.
- Conditions
- Colon Cancer, Colon Disease, Colon Cleansing
- Trial name
- NCT05174845
- Testing
- 1L PEG + ASCORBIC ACID
- Where
- 12 sites in Portugal, Spain
- Volunteers
- 13,393 people
- Sponsor
- Norgine
Atrial Fibrillation
Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
The purpose of this study is to determine whether vitamin C is effective in the prophylaxis of post-operative atrial fibrillation in on-pump cardiac surgery
- Trial name
- NCT01107730
- Testing
- Vitamin C, L-Carnitine
- Where
- Greece
- Volunteers
- 33 people
- Sponsor
- Attikon Hospital
Metabolic Syndrome
Effect of Laser Acupuncture on Metabolic Syndrome in Obese Postmenopausal Women
Thirty postmenopausal women were collected from outpatient clinic of faculty of physical therapy in Benha University to participate in this study.
- Trial name
- NCT05651451
- Testing
- Laser acupuncture, energy-restricted diet
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Anemia
Trial of Pre-Pregnancy Supplements
The purpose of this study is to determine whether daily oral supplements of multivitamins (including vitamins B-complex, C and E) along with Iron and folic acid given to non-pregnant women results in lower prevalence of anemia in…
- Trial name
- TOPPS (NCT01183572)
- Testing
- Multivitamins, Folic Acid, and Iron, Folic Acid and Iron, Folic Acid
- Where
- Tanzania
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Obstetric Labor Complications, Fever
Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes…
- Trial name
- EIVCIMFAELA (NCT06354582)
- Testing
- Vitamin C Injection, Normal saline
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kunyue Li
Multiple Myeloma
High Dose Ascorbic Acid for Plasma Cell Disorders
This is a Phase I single-arm open-label clinical study primarily assessing the safety and secondarily, the relative efficacy of low dose melphalan + high dose ascorbate acid (HDAA) in relapsed refractory patients with multiple…
- Trial name
- NCT03602235
- Testing
- Ascorbate, Melphalan
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Christopher Strouse
Will Consuming Eggs With a Mixed Vegetable Salad Increase Carotenoid Absorption
Effects of Egg Consumption on Carotenoid Absorption From Co-consumed, Non-Egg Food
The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily but average intake of US adults is only 2.6 cups.
- Trial name
- NCT01951313
- Testing
- Egg consumption
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Purdue University
Charcot-Marie-Tooth Disease, Hereditary Motor and Sensory Neuropathies
Ascorbic Acid Treatment in CMT1A Trial (AATIC)
Charcot-Marie-Tooth type IA (CMT1A) is the most prevalent hereditary peripheral neuropathy. Demyelination of peripheral nerves is the hallmark of CMT1A.
- Trial name
- AATIC (NCT00271635)
- Testing
- ascorbic acid
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colorectal Cancer
Screening Tests in Detecting Colorectal Cancer
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for colorectal cancer. PURPOSE: Randomized screening trial to compare the effectiveness of fecal occult blood testing with…
- Trial name
- NCT00025025
- Testing
- sample testing
- Where
- 65 sites in United States
- Volunteers
- 4,482 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Metabolic Syndrome
Coenzyme Q10 and Vitamin A, C, E in Relation to the Oxidative Stress, Antioxidant Enzyme Activity and Inflammation in Subjects With Metabolic Syndrome
Metabolic syndrome (MS) is a significant risk factor of cardiovascular disease. However, the relationships between coenzyme Q10, antioxidant vitamins (Vitamin A, C, E) and the prevention of the risk of MS are still inconsistent.
- Trial name
- NCT01412476
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Metastatic Pancreatic Cancer, Terminal Cancer
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of vitamin C in improving the quality of life for metastatic pancreatic cancer patients who are resistant to chemotherapy.
- Trial name
- PTCA199-4 (NCT06018896)
- Testing
- Ascorbate
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fudan University
Lymphoma, T-Cell
Durvalumab in Different Combinations With Pralatrexate, Romidepsin and Oral 5-Azacitidine for Lymphoma
This is an open-label, Phase 1/2a, dose-finding study with an initial phase 1 portion, articulated in four separate treatment arms, followed by a dedicated phase 2 for qualifying treatment Arm(s).
- Trial name
- NCT03161223
- Testing
- Durvalumab, Pralatrexate, Romidepsin
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Virginia
Respiratory Tract Infections (RTI), Meningitis
Immune-Mitochondrial Correction in Military Recruits
The goal of this clinical trial is to learn if a new immune-mitochondrial correction strategy works better than standard vitamins to prevent infections in young male military recruits during their first 6 months of service.
- Conditions
- Respiratory Tract Infections (RTI), Meningitis, Primary Prevention/Methods, Primary Prevention
- Trial name
- IMMU-MITO (NCT07622147)
- Testing
- Multivitamin/Mineral supplements, Sodium nucleinate combination
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MIPO Clinic
Spinal Cord Injuries, Endothelial Dysfunction
Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury
Heart attacks and strokes are among the most common causes of premature death in individuals living with spinal cord injury (SCI) and appear to occur earlier in life.
- Conditions
- Spinal Cord Injuries, Endothelial Dysfunction, Testosterone Deficiency
- Trial name
- NCT07227740
- Testing
- Intra-arterial Infusion of Vasoactive Agents, Intra-arterial Vitamin C Infusion, Blood Sampling
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Craig Hospital
Vitamin C Anemia, Pregnancy Anemia
The Effect of Vitamin C for Iron Supplementation During Pregnancy with Risk of Anemia
Anemia is a common problem during pregnancy. Most studies have demonstrated that anemia during pregnancy have adverse effects on their pregnancy outcome, which is important and should pay attention to prevent and solve such…
- Trial name
- NCT05975125
- Testing
- Vitamin C 500 MG Oral Tablet
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Oxygen, Hyperoxemia
Cerebral Hemodynamic Effects of Oxygen and Antioxidants (CHEOXANT)
This study is called CHE-OX-ANT (Cerebral Hemodynamic Effects of Oxygen and Antioxidants). It is a single-center, academic research project led by the Department of Intensive Care at Erasme Hospital (Université Libre de…
- Conditions
- Oxygen, Hyperoxemia, Antioxidant, Cerebral Autoregulation
- Trial name
- CHEOXANT (NCT07369232)
- Testing
- Oxygen, Vitamin C (Ascorbic Acid)
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
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