Clinical trials: Vitamin C
Post-acute COVID-19 Syndrome
The Effect of Micellized Food Supplements on Health-related Quality of Life in Patients With Post-acute COVID-19 Syndrome.
Food supplements like curcumin and boswellia serrata have been used traditionally for anti-inflammatory purposes. A well-known problem of these substances in their natural form is the low bioavailability.
- Trial name
- NCT05150782
- Testing
- Curcumin/Boswellia Serrata/Ascorbic acid mixture
- Volunteers
- 32 people
- Sponsor
- PhysioMetrics
Olfactory Disorder
Intranasal Retinoic Acid Treatment for Patients With OlfactoryLOSS: A RANDOMIZED CONTROLLED TRIAL
About One to 2 percent of the North American population below the age of 65 years experience olfactory loss to a significant degree.
- Trial name
- NCT03574701
- Testing
- Vitamin A
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- St. Paul's Hospital, Canada
HIV Infections, Pregnancy Complications
Trial of Vitamins Among Children of HIV-infected Women
The purpose of this study is to examine the effects of multivitamin (B, C, E) supplementation on reducing the risk of morbidity and mortality outcomes among children born to HIV positive mothers, compared to placebo…
- Trial name
- NCT00197730
- Testing
- Multivitamins - vitamins B complex, C and E
- Where
- Tanzania
- Volunteers
- 2,387 people
- Sponsor
- Harvard School of Public Health (HSPH)
Nutrition, Healthy
Oral Nutritional Supplements in Treatment of Elderly Mild-to-Moderate COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has seriously threatened public health worldwide. Nutritional supplements may have a positive influence on the recovery of patients with viral infection.
- Trial name
- ONSITEMC (NCT05629975)
- Testing
- Oral Nutritional Supplements
- Volunteers
- 150 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Malaria
Micronutrients and Child Health Study
The purpose of this study is to determine to what extent supplementation with zinc and other micronutrients are efficacious in preventing malaria in young Tanzanian children.
- Trial name
- MACH (NCT00623857)
- Testing
- Zinc, Vitamins and minerals other than zinc, Vitamins plus zinc and other minerals
- Where
- Tanzania
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Myelodysplastic Syndromes, Myeloproliferative Neoplasm
TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid
The purpose of this study is to evaluate the efficacy of treatment with azacitidine (an FDA approved drug for the treatment of MDS) and high dose ascorbic acid in patients with TET2 mutations.
- Conditions
- Myelodysplastic Syndromes, Myeloproliferative Neoplasm, Acute Myeloid Leukemia
- Trial name
- NCT03397173
- Testing
- Azacitidine, Ascorbic acid
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Case Comprehensive Cancer Center
SARS-CoV-2 Infection (COVID-19)
Australasian COVID-19 Trial (ASCOT) ADAptive Platform Trial
An International Multi-Centre Randomised Adaptive Platform Clinical Trial to Assess the Clinical, Virological and Immunological Outcomes in Patients with SARS-CoV-2 Infection (COVID-19).
- Trial name
- ASCOT (NCT04483960)
- Testing
- (Arm Closed) Nafamostat Mesilate, (Arm Closed) Enoxaparin, (Arm Closed) Dalteparin
- Where
- 25 sites in Australia
- Volunteers
- 2,200 people
- Sponsor
- University of Melbourne
Septic Shock, Sepsis
Vitamin C to Reduce Vasopressor Dose in Septic Shock
Randomized, controlled, double blind clinical trial. Adult patients admitted to the ICU of the Hospital Español de México with a diagnosis of septic shock will be included.
- Trial name
- ViCiS (NCT03835286)
- Testing
- Vitamin C
- Where
- Mexico
- Sponsor
- Hospital Español de Mexico
Severe Sepsis
Outcome Following Vitamin C Administration in Sepsis
This study is designed to determine if Vitamin C administration to septic patients will result in an improvement in organ dysfunction which occurs during a septic illness. Hypothesis: 1.
- Trial name
- NCT01590303
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
HCC
Treatment of Intermediate-stage Hepatocellular Carcinoma
The purpose of this study is to evaluate the efficacy and safety of transarterial chemoembolization (TACE) combined with arginine hydrochloride and trimetazidine hydrochloride tablets in the treatment of patients with…
- Trial name
- TIHCC (NCT03274427)
- Testing
- Basic drugs therapy of HCC by TACE, Arginine hydrochloride, Trimetazidine hydrochloride
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Evaluating Whole Foods Supplementation on Cognition
A six-month study which investigated the effect of Ginkgo Synergy® and Choline or OPC Synergy® and Catalyn® on cognitive and immune function markers and quality of life among healthy older adults with no history of significant…
- Trial name
- NCT01672359
- Testing
- Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Miami
COVID-19
Efficacy and Safety of High-dose Vitamin C Combined With Chinese Medicine Against Coronavirus Pneumonia (COVID-19)
In December 2019, coronavirus pneumonia (COVID-19) was detected in many cases in Wuhan, China. With the rapid spread of the coronavirus, cases of COVID-19 were also reported in other cities of China and other countries.
- Trial name
- NCT04664010
- Testing
- Alpha-interferon alpha, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste, fumigation/inhalation of vitamin C, Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and 5% glucose, Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and high-dose vitamin C treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xi'an International Medical Center Hospital
Cicatrix
Efficacy and Safety of Silicone Cream Containing Allium Cepa Extract
The objectives of this study were to evaluate efficacy and safety of silicone cream containing Allium Cepa extract in post-cesarean surgical scars treatment.
- Trial name
- NCT04233320
- Testing
- silicone cream containing Allium Cepa extract, Commercial scar gel
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Skin Carotenoids
Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit…
- Trial name
- NCT07513597
- Testing
- Dietary Supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Liver Cirrhoses, Chronic Hepatitis c
Hematologic Profile, Vit. B12 and Folic Acid in Cirrhotics Received Sofosbuvir and Daclatasvir With or Without Ribavirin
Use of Ribavirin could affect hematologic profile of the patients negatively. With advent of new antiviral therapy, the preexisting hematologic changes may alter or corrected after treatment.
- Conditions
- Liver Cirrhoses, Chronic Hepatitis c, Directly Acting Antivirals
- Trial name
- NCT03283176
- Testing
- Vitamin B12 and Folic Acid
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma
Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery
This randomized phase II trial studies how well pazopanib hydrochloride with or without ascorbic acid work in treating patients with kidney cancer that has spread to other places in the body (metastatic) or cannot be removed by…
- Conditions
- Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v7
- Trial name
- NCT03334409
- Testing
- Ascorbic Acid, Pazopanib Hydrochloride
- Where
- 5 sites in United States
- Volunteers
- 5 people
- Sponsor
- Academic and Community Cancer Research United
Skin Condition, Anti-Oxidative Stress
Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet
The objective of this study is to evaluate the effect of liquid vitamin C and glutathione supplements on human skin condition improvement and anti-oxidation.
- Trial name
- NCT07379216
- Testing
- Vitamin C and Glutathione Liquid Sachet
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Higher Uric Acid Concentrations (>5,5 mg/dl), Healthy
Influence of Hesperidin and Vitamin C on Uric Acid Concentration
Aim of the study is to investigate the impact of hesperidin and/or vitamin C on elevated uric acid concentrations.
- Trial name
- HesperiDrinC (NCT04316390)
- Testing
- Control, Hesperidin, Vitamin C
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Sepsis and Septic Shock
Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in Sepsis
This two-center, open-label randomized controlled trial evaluated the effect of adjunctive thiamine, ascorbic acid, and their combination compared with 0.9% saline on the extracellular matrix-remodeling axis (matrix…
- Trial name
- NCT07786350
- Testing
- Thiamine, Ascorbic Acid Injectable Product, Normal Saline 0.9% Injectable Solution
- Where
- 2 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Sumatera Utara
Colon Preparation, Polyps Colorectal
Efficacy And Tolerability Of Asymmetric Split Regimen For Bowel Preparation
The investigators aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on…
- Trial name
- NCT06916689
- Testing
- 1L PEG-Asc
- Where
- Italy
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense
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