Clinical trials: Vitamin C
Nonmelanoma Skin Cancer, Basal Cell Carcinoma
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)
This research study is for people who have been diagnosed with a nonmelanoma skin cancer (either basal cell carcinoma or squamous cell carcinoma) and are planning to receive either Mohs surgery or ED\&C (electrodessication \&…
- Conditions
- Nonmelanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT07241585
- Testing
- Vitamin D (VitD), Photodynamic therapy (PDT), Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Case Comprehensive Cancer Center
Overweight and Obesity, Inflammation
Clinical Trials of Five Different Food Supplements With Restriction Diet in Adults
In recent years, dietary supplement are of great interest for the improvement of human health. This study is designed as a parallel, randomized, double blind study exploring the efficacy of two months daily oral dosing of five…
- Conditions
- Overweight and Obesity, Inflammation, Hypercholesterolemia, Hypertension
- Trial name
- FOODSU (NCT05333315)
- Testing
- IP1, IP2, IP3
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Overactive Bladder
Efficacy and Safety Study of Botulinum Toxin Type-A (Dysport®) in Continent Female Subjects Suffering From Idiopathic Overactive Bladder
The purpose of this study is to determine the optimal dose of botulinum toxin type A injected in the detrusor muscle to improve urinary symptoms, urodynamic parameters and quality of life of continent women suffering from…
- Trial name
- NCT00578097
- Testing
- Botulinum toxin type A
- Where
- 34 sites in Belgium, Czechia and 6 more
- Volunteers
- 81 people
- Sponsor
- Ipsen
Anemia
Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children
Anemia continues to be a major public health problem in many regions of the world and it is still not clear which strategy is more effective in children population in terms of adherence and efficacy.
- Trial name
- NCT00822380
- Testing
- Iron, Multiple micronutrients supplement, micronutrient fortified porridge powder
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Queretaro
COVID-19
The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection
Based on data regarding the effect of colchicine on the modulation of immune system and decreasing cytokine release and inflammation the question arises whether colchicine, administered in a relatively low dose, could potentially…
- Trial name
- NCT04360980
- Testing
- Colchicine Tablets
- Where
- 2 sites in Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Mental Health Disorders
Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance
Specific Aim #1: Examining the impact of mental health disorders (PTSD and GAD) on peripheral vascular function and sympathetic nervous system activity in young individuals.
- Trial name
- NCT03216980
- Testing
- PTSD/GAD Antioxidant, Healthy Control Antioxidant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Child Nutritional Status, Household Dietary Diversity
Impact Evaluation of the DFID Programme to Accelerate Improved Nutrition of the Extreme Poor in Bangladesh
This is a randomized study in three areas of Bangladesh (Chars region where CLP operates, Haor region where Shiree operates, and urban slums where UPPR operates).
- Conditions
- Child Nutritional Status, Household Dietary Diversity, Maternal Nutrition Knowledge and Practices
- Trial name
- NCT02597608
- Testing
- CLP: Livelihoods, CLP: Nutrition, Shiree: Livelihoods
- Where
- Bangladesh
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Type 2 Diabetes
Hyperglycemia and Oxidative Stress in the Human Brain With Diabetes
The purpose of this study is to use an MRI exam to measure the concentrations of glutathione (GSH) and Vitamin C (Asc) in the brains of normal healthy persons and type 2 diabetic persons.
- Trial name
- NCT00775541
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- In-Young Choi, Ph.D.
Wounds and Injuries, Malnutrition
Individualized Nutritional Care Bundle for Home Nursing Patients With Pressure Injuries.
Objective: To evaluate the impact of an individualized nutrition intervention package on pressure injury healing rates, prevention of new pressure injuries, complications, quality of life, and cost-effectiveness in adult on home…
- Conditions
- Wounds and Injuries, Malnutrition, Nutritional Deficiency, Wound Healing Delayed
- Trial name
- INCA (NCT06078488)
- Testing
- Individualized and Protocolized Nutritional Care Bundle, Optimized Standard Care
- Where
- Singapore
- Volunteers
- 380 people
- Sponsor
- Changi General Hospital
Systemic Lupus Erythematosus (SLE)
Efficacy of Vitamin C Supplementation on Malondialdehid Levels and Disease Activity in SLE Patients
The study aimed to evaluate the efficacy of vitamin C supplementation compared to placebo towards malondialdehid levels and disease activity with the MEX-SLEDAI score in Systemic Lupus Erythematosus (SLE) patients.
- Trial name
- NCT07083622
- Testing
- Vitamin C
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Sriwijaya
Covid19
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients
A randomized controlled trial on using Ivermectin and doxycycline to treat mild-moderate outpatients, severe, and critical inpatients of Coronavirus disease 19 (COVID-19) along with standard of care.
- Trial name
- NCT04591600
- Testing
- Ivermectin and Doxycyline, Standard of care
- Where
- Iraq
- Volunteers
- 140 people
- Sponsor
- Alkarkh Health Directorate-Baghdad
Patients Undergoing Screening or Surveillance Colonoscopy
Single Center Comparison of 4 FDA Approved, Commercially Available Bowel Purgatives for Colonoscopy
This will be a 4-way comparison to prospectively evaluate the efficacy and patient tolerability of four commercially available bowel preparations among patients undergoing colonoscopy for screening and surveillance in a single…
- Trial name
- NCT02124447
- Testing
- PEG+E, PEG+Asc, P+MC
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Photoaging
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging
Our study involves the evaluation of a high potency peel in its efficacy for skin rejuvenation in the treatment of photoaging. This chemical peel regime is a high potency peel 70% glycolic acid combined with vitamin C that is…
- Trial name
- NCT02126644
- Testing
- 70% glycolic acid
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Small Cell Lung Cancer
To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid
The purpose of this research study is to test a tumor (cancer) vaccine given along with chemotherapy to determine if this vaccine will increase the chances of the tumor shrinking and/or the amount of time that people who have…
- Trial name
- NCT00617409
- Testing
- Paclitaxel, Drug: Ad.p53-DC vaccines, All -trans Retinoic Acid (ATRA)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Ageing
Exploratory Study on the Role of Vitamin C in Promoting Health in Middle-Aged and Elderly Adults
The purpose of this clinical trial is to understand whether oral vitamin C can help delay the aging of middle-aged and elderly individuals, search for sensitive biomarkers of human aging, and provide new paradigms and scientific…
- Trial name
- VitC-Aging (NCT06794255)
- Testing
- Vitamin C
- Where
- 3 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
THALASSEMIA MAJOR
Reproductive Capacity and Iron Burden in Thalassemia
The improved long-term survival of thalassemia major (TM) patients has resulted in increased focus on the ability to preserve fertility.
- Trial name
- Fertility thal (NCT02308904)
- Testing
- Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary MRI
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Facioscapulohumeral Muscular Dystrophy
Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
On the basis of published data and the investigators' results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, the investigators propose a study to test whether…
- Trial name
- FSHD (NCT01596803)
- Testing
- Taking of blood, needle biopsy of the vastus lateralis muscle, Vit C Vit E Zn Se
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Restless Legs Syndrome
Alpha-lipoic Acid Combined With B Vitamins Shows Promise for Treating Restless Legs Syndrome
Investigating Tiobec® 400's efficacy in alleviating Restless Legs Syndrome symptoms sheds light on promising therapeutic avenues.
- Trial name
- NCT06324760
- Testing
- Alpha-lipoic acid combined with B vitamins
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Uriach Consumer Healthcare
Hypochlorhydria
Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets
This study evaluates the use of ascorbic acid, vitamin C, to temporary reduce gastric pH in individuals with omeprazole induced hypochlorhydria.
- Trial name
- NCT04199624
- Testing
- Omeprazole 20mg, Vitamin C
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Periorbital Area
A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area
This study will evaluate the efficacy of the DIME Beauty Luminosity Eye Serum in improving the appearance of skin in the periorbital eye area. This study will last for 60 days.
- Trial name
- NCT06143033
- Testing
- DIME Beauty Luminosity Eye Serum
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
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