Clinical trials: Vitamin C
Iron Deficiency
Evaluation of Iron Bioavailability From Iron Chlorophyllin
The overall objective of this study is to evaluate the iron absorption from iron chlorophyllin. Iron deficiency is a public health problem in both developing and industrialized countries.
- Trial name
- NCT04602247
- Testing
- SIC, SIC + AA combined, FeSO4
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
NPMc+ AML
Oral Arsenic Trioxide for NPM1-mutated AML
A prospective open-label phase 2 study will be designed to assess the efficacy of oral arsenic trioxide plus azacitidine in preventing relapses in patients with NPM1-mutant AML.
- Trial name
- NCT04689815
- Testing
- Oral Arsenic Trioxide Formulation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
COVID-19 Pneumonia
Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia
As of August 16, 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for more than 21 294 000 infections and about 760 000 deaths worldwide.
- Trial name
- COral-MAF1 (NCT04845971)
- Testing
- Saisei Maf capsules
- Where
- Italy
- Volunteers
- 97 people
- Sponsor
- Dr. Spadera Lucrezia
Healthy
Genetic Information and Dietary Intake Behaviour
This study's primary objective is to determine if providing individuals with personal genetic information impacts dietary intake behaviour.
- Trial name
- NCT01353014
- Testing
- Dietary advice with genetic information, General dietary recommendations
- Where
- Canada
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Collagen Synthesis, Rate of Force (RFD) Development
Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance
Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes
- Trial name
- NCT04437758
- Testing
- Collagen and Vitamin C powder mix nutritional intervention, Maximum power training exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Heart Failure With Normal Ejection Fraction
Treatment of HFpEF With Nitrate Supplement
The objective of this project is to determine if Neo40, a nitric oxide generating lozenge, when consumed twice daily by subjects with HFpEF, will increase exercise tolerance, decrease symptoms and improve quality of life for…
- Trial name
- NCT03289481
- Testing
- Active lozenge
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- MaineHealth
Healthy
Study Assessing Dosing Time and Calcium and Vitamin D on the Relative BA of 35 mg DR Risedronate Dosed With Food
Randomized, open-label, single dose, 3-treatment, 3-period crossover study, with a 14- to 17-day washout period between doses. The study will consist of a screening visit, study center admission (preceding Treatment Periods 1, 2…
- Trial name
- NCT00868907
- Testing
- 35 mg risedronate DR tablet
- Where
- 4 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Infections, Respiratory Tract
An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu
The purpose of the study is to assess the short term efficacy of the Theraflu Night powder for oral solution in the Russian population in "Short term relief of the symptoms of colds, chills and influenza, including mild to…
- Trial name
- NCT02730364
- Testing
- Paracetamol, phenylephrine HCl, pheniramine maleate, and vitamin C
- Sponsor
- GlaxoSmithKline
Formula Milk, Breast Milk Collection
Metabolomic Profile in Breastfed Late Preterm Infants
Exclusive breast milk is recommended from birth to 6 months of life to promote the development of a balanced intestinal microbiota.
- Conditions
- Formula Milk, Breast Milk Collection, Postbiotic Supplemented Formula Milk
- Trial name
- NCT06052592
- Testing
- Milk
- Where
- 2 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Melasma
Fractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma.
The aim of the study: 1.To compare the efficacy and safety of fractional CO2 laser in combination with vitamin c and tranexamic acid in the treatment of melasma.
- Trial name
- NCT05911698
- Testing
- Fractional co2 laser
- Volunteers
- 25 people
- Sponsor
- Khadija Qenawi
COVID-19, Coronavirus Infection
A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection
This is a Phase II interventional study testing whether treatment with hydroxychloroquine, Vitamin C, Vitamin D, and Zinc can prevent symptoms of COVID-19
- Conditions
- COVID-19, Coronavirus Infection, Sars-CoV2, Corona Virus Infection
- Trial name
- HELPCOVID-19 (NCT04335084)
- Testing
- Hydroxychloroquine, Vitamin C, Vitamin D
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Chronic Kidney Disease, Kidney Transplantation
Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients
People with kidney transplants often develop bone disease. One reason for bone disease may be overactivity of a gland in the neck called the parathyroid gland.
- Trial name
- NCT00889629
- Testing
- Doxercalciferol, 25-OH Vitamin D3
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mariana Markell
Endothelial Dysfunction
A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction
This Phase 2, randomized, open-label, 2-treatment, 2-sequence, 2-period crossover, pharmacokinetic (PK) study will compare plasma concentrations of BH4 in subjects with endothelial dysfunction following 14 days of treatment by…
- Trial name
- NCT00532844
- Testing
- Sapropterin Dihydrochloride, Sapropterin Dihydrochloride and Vitamin C
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- BioMarin Pharmaceutical
Implant Stability and Osseointegration
Topical Dexamethasone, Ascorbic Acid, and BGP for Enhancing Implant Osseointegration
The goal of this clinical trial was to evaluate whether the topical application of a combination of dexamethasone, ascorbic acid, and β-sodium glycerophosphate could enhance implant osseointegration in adult dental implant…
- Trial name
- DAG (NCT07060859)
- Testing
- Topical Application of Dexamethasone, Ascorbic Acid, and β-Sodium Glycerophosphate
- Where
- Palestinian Territories
- Volunteers
- 18 people
- Sponsor
- Manar Ziad Foura-Matar
Postoperative Pulmonary Complications
Effect of Ascorbic Acid on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery
Postoperative pulmonary complications(PPCs) including, but not limited to ,hypoxemia, pneumonia, ventilator-induced lung injury, and acute respiratory distress syndrome (ARDS),atelectasis,pleural effusion .PPCs may result in…
- Trial name
- NCT03756727
- Testing
- Ascorbic Acid, Saline
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xuzhou Medical University
Type 2 Diabetes Mellitus
Bone Marrow Derived Stem Cell Transplantation in T2DM
The purpose of this study is to improve the blood glucose level in type 2 diabetic patients.
- Trial name
- NCT01759823
- Testing
- mesenchymal stem cell transplantation, control, MNC's TRANSPLANTATION
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Facioscapulohumeral Muscular Dystrophy
Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
On the basis of published data and the investigators' results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, the investigators propose a study to test whether…
- Trial name
- FSHD (NCT01596803)
- Testing
- Taking of blood, needle biopsy of the vastus lateralis muscle, Vit C Vit E Zn Se
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Cancer
New Treatment Option for Pancreatic Cancer
In the United States, approximately 30,000 new cases of pancreatic cancer are diagnosed each year and an almost equal number of deaths are related to this cancer.
- Trial name
- NCT01364805
- Testing
- Intravenous Vitamin C, Gemcitabine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Jeanne Drisko, MD, CNS, FACN
Acute Mountain Sickness
Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness
Acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), and high altitude cerebral edema (HACE) are complications of rapid ascent to high altitude.
- Trial name
- NCT00664001
- Testing
- Anti-oxidant supplementation
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Altitude Physiology Expeditions
Chronic Obstructive Pulmonary Disease
Detection of Aspergillus Fumigatus and Sensitization in COPD Patients With Bronchiectasis vs Without Bronchiectasis
A single center case-control study with 100 COPD patients will be organized to compare patients with and without bronchiectasis with regard to the presence of Aspergillus in sputum samples, Aspergillus sensitization and vitamin…
- Trial name
- NCT02332122
- Testing
- Sputum induction, Skin prick test, Questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Wim Janssens
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