Clinical trials: Vitamin C
Anemia
Monitoring and Evaluation of Micronutrients (Sprinkles) Project
The purpose of this study is 1) to evaluate the effectiveness in reducing anemia among children 6-24 months of age by providing daily micronutrient Sprinkles through the Government of Pakistan's Lady Health Worker program; 2) to…
- Trial name
- Sprinkles (NCT00659061)
- Testing
- SPRINKLES, Nutrition education
- Where
- Pakistan
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Liver Transplant Failure and Rejection
Parenteral Ascorbic Acid Repletion in TransplantatIon
A single-center, randomized, double-blinded placebo-controlled trial is proposed to investigate administration of supraphysiologic doses of ascorbic acid (vitamin C, AA) to patients undergoing liver transplantation.
- Trial name
- PARTI (NCT04756063)
- Testing
- Ascorbic acid
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Acute Promyelocytic Leukemia (APL), Acute Promyelocytic Leukaemia
A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301)
LATITUDE: A Phase 3, Randomized, Open-Label, 3-Cohort, 2-Period, 2- Sequence, Crossover Trial to Evaluate the Pharmacokinetics, Safety, and Efficacy of Oral Arsenic Trioxide Versus Intravenous Arsenic Trioxide for Consolidation…
- Conditions
- Acute Promyelocytic Leukemia (APL), Acute Promyelocytic Leukaemia, Acute Promyelocytic Leukemia With PML-RARA, Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA
- Trial name
- LATITUDE (NCT07296445)
- Testing
- Oral ATO, IV Arsenic Trioxide, all-trans retinoic acid (ATRA)
- Volunteers
- 120 people
- Sponsor
- SDK Therapeutics, Inc.
Covid19
Dietary Supplements for COVID-19
This is a double blind, placebo controlled, phase III randomized controlled trial evaluating the effects of the dietary supplements vitamin C, vitamin D, vitamin K, and zinc versus placebo on the overall health, symptom severity…
- Trial name
- NCT04780061
- Testing
- Vitamin D3 50,000 IU, Vitamin C/Zinc, Vitamin K2/D
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- The Canadian College of Naturopathic Medicine
COVID-19, Corona Virus Infection
A Study of Quintuple Therapy to Treat COVID-19 Infection
This is a Phase II interventional study will test the efficacy of quintuple therapy (Hydroxychloroquine, Azithromycin, Vitamin C, Vitamin D, and Zinc) in the treatment of patients with COVID-19 infection).
- Conditions
- COVID-19, Corona Virus Infection, Coronavirus-19, Sars-CoV2
- Trial name
- HAZDpaC (NCT04334512)
- Testing
- Hydroxychloroquine, Azithromycin, Vitamin C
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- ProgenaBiome
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Acne
RCT of an Oral Acne Supplement for Adult Women
This study is to assess the efficacy and tolerability of an oral supplement in mild to moderate acne in adult females.
- Trial name
- NCT06097871
- Testing
- Skin Nutraceutical Supplement
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Nutraceutical Wellness Inc.
Asthma
Integrative Medicine Approach to the Management of Asthma in Adults
The overall aim of this research project is to test the effectiveness of an integrative program, using journaling, yoga breathing instruction, and nutritional manipulation and supplementation, on quality of life and clinical…
- Trial name
- NCT00843544
- Testing
- Integrative Medicine
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Beth Israel Medical Center
Healthy, Suboptimal Vitamin C Levels
The Impact of Qualia Vitamin C+ on Blood Vitamin C Levels
This is a double-blind, placebo-controlled, parallel-group, study evaluating the effect of a Qualia Vitamin C+ formulation on Whole Blood Vitamin C levels in the blood of healthy adults aged 25 years or older.
- Trial name
- NCT07285109
- Testing
- Qualia Vitamin C+
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Atrial Fibrillation
Influence of Vitamin C on Post-operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is the most common arrhythmia which typically develops 2-3 days after cardiac surgery.
- Trial name
- NCT03592680
- Testing
- Vitamin C
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Lack or Loss Appetite Nonorganic Origin
Efficacy and Tolerability of Apevitin BC Comparing to Vitamin Complex in Stimulating the Appetite
Lack of appetite is one of the most common reasons for visits to pediatric clinics.The symptoms usually manifest after weaning when they are introduced into the diet of infant foods containing salt.Is normally used to…
- Trial name
- Inappetence (NCT01283646)
- Testing
- Apevitin BC, Vitamin B Complex + Vitamin C
- Where
- 3 sites in Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- EMS
Cholera, Vibrio Infections
Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults
The purpose of this study is to assess the safety and immunogenicity of Peru-15 (CholeraGarde®) vaccine in HIV seropositive adult population of Bangkok Thailand
- Conditions
- Cholera, Vibrio Infections, Diarrhea
- Trial name
- NCT00741637
- Testing
- CholeraGarde®
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- International Vaccine Institute
Major Trauma, Sepsis
Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis
The occurrence of sepsis in trauma patients is a very serious complication. Identifying trauma patients at high risk of sepsis was not revealed in the latest surviving sepsis campaign in 2016.
- Trial name
- DrNoha-ICU (NCT04216459)
- Testing
- oral lactobacillus probiotics plus intramuscular cholecalciferol, intravenous vitamin C plus thiamine
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Mansoura University
CD20+ Aggressive B-Cell Lymphoma
OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients with CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine
The purpose of this study is to improve the outcome of elderly patients with CD20-Aggressive B-Cell Lymphoma and to reduce the toxicity of standard used Immuno-Chemotherapy by using an optimised schedule of the monoclonal…
- Trial name
- OPTIMAL>60 (NCT01478542)
- Testing
- Conventional Vincristine, Liposomal Vincristine, Ricover-scheme rituximab
- Where
- 127 sites in Germany
- Volunteers
- 1,152 people
- Sponsor
- Universität des Saarlandes
Iron Absorption
Iron Bioavailability of Fortified Oat Drink
This study will follow a double blinded randomized controlled study design to enroll 20 apparently healthy 6 year old children. The children will be fed with two different nutrient fortified oat drinks labeled with stable…
- Trial name
- NCT01423162
- Testing
- Dietary Intervention (with Vit C then without Vit C), Dietary Intervention (without Vit C followed by with Vit C)
- Where
- Philippines
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Catheter-Associated Urinary Tract Infection
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT05913180
- Testing
- Ascorbic Acid 1000 MG
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- American University of Beirut Medical Center
Gingivitis, Orthodontic Appliance Complication
Derma Pen as Treatment of Gingivitis Induced by Orthodontics
Although orthodontic therapy frequently improves tooth alignment and appearance, its problems with oral hygiene can make patients highly susceptible to gingivitis. After orthodontic treatment, gingivitis is a typical problem.
- Trial name
- NCT06567405
- Testing
- mechanical periodontal treatment, Derma pen with topical ascorbic Acid
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Safa Basiouny Alawy
Fatigue, Breast Cancer
Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Neoadjuvant and Adjuvant Chemotherapy
The goal of this clinical trial is to test the effect of the administration of APPORTAL® in addition to the SoC (recommended physical exercise), in patients with breast cancer, suffering from fatigue during neoadjuvant and…
- Trial name
- NCT06137833
- Testing
- APPOPRTAL®
- Where
- 5 sites in Italy
- Volunteers
- 92 people
- Sponsor
- Pharmanutra S.p.a.
Colorectal Disorders
The Use of Osmotic Laxatives Versus Macrogol for Bowel Preparation in Patients Undergoing Colonoscopy
The gold standard of colorectal examination is colonoscopy. One of the main purposes of colonoscopy is detecting bowel neoplasms. Right now there are several methods the bowel preparation for the colonoscopy.
- Trial name
- CLEAN (NCT04225793)
- Testing
- Eziklen®, MoviPrep
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- Russian Society of Colorectal Surgeons
Peri-implant Mucositis
Propolis Extract, Nanovitamin C and Nanovitamin E in Peri-implant Mucositis
The objective of this study was to perform the first clinical trial to evaluate the effectiveness of propolis extract, nanovitamin C and nanovitamin E gel as adjuvant to mechanical debridement in clinical and microbiological…
- Trial name
- NCT04215432
- Testing
- Gel containing propolis extract, nanovitamin C and nanovitamin E
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidad Complutense de Madrid
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