Clinical trials: Vitamin C
Healthy Person, Bowel Preparation Before Colonoscopy
Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
comparison of the use of Colyte® (ascorbic acid mixed polyethylene glycol solution) in two-liter versus one-liter volume and pretreatment with bisacodyl for colonoscopy preparation.
- Trial name
- NCT01745835
- Testing
- 2L Coolprep®, 1L Coolprep® and Bisacodyl
- Where
- South Korea
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Coronary Artery Disease
Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers
The objective of this study is to demonstrate the primary hypothesis that, in patients with chronic and acute coronary syndromes requiring percutaneous coronary intervention (PCI), the novel sirolimus-ascorbic acid eluting stent…
- Trial name
- NOVA (NCT07566091)
- Testing
- Sirolimus-Ascorbic Acid Eluting Stent, Everolimus-Eluting Stent
- Where
- South Korea
- Volunteers
- 2,034 people
- Sponsor
- Jung-min Ahn
Shock, Septic, Critically Ill
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
Sepsis has been characterised as a dysregulated host response to infection. Adjunctive therapies targeting the inflammatory cascade are being increasingly explored, although to date, have failed to demonstrate consistent benefit…
- Conditions
- Shock, Septic, Critically Ill, Vasoplegic Syndrome, Sepsis
- Trial name
- VITAMINS (NCT03333278)
- Testing
- Vitamin C, Thiamine, Hydrocortisone,
- Where
- 8 sites in Australia, Brazil and 1 more
- Volunteers
- 216 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Carcinoma, Non-Small-Cell Lung
Pharmacological Ascorbate for Lung Cancer
This clinical trial evaluates adding high-dose ascorbate (vitamin C) to standard of care treatment of non-small cell lung cancer (NSCLC) in adults.
- Trial name
- NCT02420314
- Testing
- Paclitaxel, Carboplatin, Ascorbic Acid
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Joseph J. Cullen, MD, FACS
Vitamin D Deficiency, Calcium
Resistive Exercise Versus HIIT on Calcium and Vitamin D
A comparison between resistive exercise and high intensity interval trainig on calcium and vitamin d in premenopausal women.
- Conditions
- Vitamin D Deficiency, Calcium, Premenopause
- Trial name
- NCT05795504
- Testing
- resistive exercise, high intensity interval training, calcium and vitamin D
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitamin C Deficiency
The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis
The effect of vitamin C supplementation on GCF total oxidant capacity in smoker patients with periodontitis following non-surgical periodontal therapy.
- Trial name
- NCT05009355
- Testing
- Vitamin C
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery.
The goal of this clinical trial is to compare the analgesic effect of melatonin, and vitamin C and their combination in patients aged 18-60 years old who will undergo major abdominal surgery with mid-line incision within an…
- Trial name
- NCT06374771
- Testing
- Melatonin 10 MG, Vitamin C
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
HCC
Treatment of Advanced Hepatocellular Carcinoma
The purpose of this study is to evaluate the efficacy and safety of arginine hydrochloride combined with trimetazidine hydrochloride tablets in the treatment of patients with hepatocellular carcinoma.
- Trial name
- TAHCC (NCT03278444)
- Testing
- Basic drugs therapy of HCC, Arginine hydrochloride, Trimetazidine hydrochloride
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Multiple Myeloma, Stem Cell Transplantation
Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients
1. To evaluate the toxicity and safety of a combination of arsenic trioxide with ascorbic acid and high-dose Melphalan in patients with multiple myeloma 2.
- Trial name
- NCT00661544
- Testing
- Arsenic Trioxide, Melphalan, Ascorbic Acid
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
Malnutrition
Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children
The purpose of this study is to measure the impact of a fortified food on the nutritional and micronutrient status of malnourished children, compared with milk.
- Trial name
- NCT01643187
- Testing
- Beverage fortified with 21 vitamins and minerals, Lactose-free milk
- Where
- Guatemala
- Volunteers
- 1,000 people
- Sponsor
- Association for the Study and Prevention of HIV/AIDS
COVID-19
Canadian Adaptive Platform Trial of Treatments for COVID-19 in Community Settings
CanTreatCOVID is an open-label, individually randomized, multi-centre, national trial. CanTreatCOVID aims to establish an adaptive platform trial aimed at evaluating the clinical- and cost-effectiveness, practical challenges, and…
- Trial name
- CanTreatCOVID (NCT05614349)
- Testing
- Paxlovid, Antioxidant
- Where
- 6 sites in Canada
- Volunteers
- 797 people
- Sponsor
- Unity Health Toronto
Acute Pain
Preventive Treatment of Pain After Dental Implant Surgery
The objective of this prospective randomized double-blind study was to evaluate the effects of the preoperative administration of dexketoprofen trometamol (DKT) on the pain perceived by patients after oral surgery for implant…
- Trial name
- UMU (NCT03107338)
- Testing
- DEXKETOPROFEN TROMETAMOL
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Blood Pressure
Effects of Dietary Nitrate and Vitamin C Co-supplementation on Blood Pressure and Endothelial Function in Overweight Individuals
The investigators have shown in two short-term studies in healthy, young participants that the combined supplementation of inorganic nitrate with vitamin C has beneficial effects on blood pressure and blood vessel wall stiffness.
- Trial name
- NCT07242066
- Testing
- Beetroot juice plus vitamin C tablet
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Vitamin D Deficiency
The Effects of Vitamin D3 Alone and in a Combination With Omega-3 on the Association of C-peptide With Glycemic Control
The Effects of Vitamin D3 alone and in a combination with omega-3 on the association of C-peptide with glycemic control
- Trial name
- NCT04307784
- Testing
- VD3, Omega-3FA, VD3 and Omega-3FA
- Where
- Jordan
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Tuberculosis, HIV
Nutrition, Diabetes and Pulmonary TB/HIV
We propose a randomised trial among pulmonary TB patients, examined and treated as part of the national TB control programme (WHO, 2003). The aim is to improve TB treatment outcome in high TB and HIV burden countries.
- Conditions
- Tuberculosis, HIV, Diabetes
- Trial name
- NCT00311298
- Testing
- Multimicronutrients, Energy and proteins
- Where
- Tanzania
- Volunteers
- 1,250 people
- Sponsor
- University of Copenhagen
Healthy
Nitrite Infusion Studies
This study will examine 1) how nitrite (a natural blood substance that relaxes blood vessels) increases blood flow and lowers blood pressure, and 2) how to increase the effects of nitrite on blood pressure.
- Trial name
- NCT00102271
- Testing
- Oxypurinol, Sodium Nitrite
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Kidney Injury
Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty
A Randomized controlled trial aiming to investigate whether ascorbic acid has a role in preventing vancomycin induced nephrotoxicity or not in critically ill patients.
- Trial name
- NCT03921099
- Testing
- Ascorbic Acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Gestational Weight Gain, Diet, Food, and Nutrition
Nutri-CAP: Nutrition for Children, Adolescent Girls, and Pregnant Women in Slums of Dhaka City
The objective of the research project is to establish an evidence-based sustainable nutrition service delivery platform for optimizing pregnancy weight gain, increasing dietary diversity of adolescent girls, and ensuring proper…
- Conditions
- Gestational Weight Gain, Diet, Food, and Nutrition, Undernutrition, Health Behavior
- Trial name
- NCT05311436
- Testing
- Experimental - Intensive nutrition counselling for pregnant, adolescent and under2 children
- Where
- Bangladesh
- Volunteers
- 3,278 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
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