Clinical trials: Vitamin C
Myeloma
Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients
Primary Objectives: 1. To evaluate the toxicity and safety of a combination of bortezomib with arsenic trioxide, ascorbic acid and high-dose melphalan in patients with multiple myeloma 2.
- Trial name
- NCT00469209
- Testing
- Trisenox (Arsenic Trioxide), Velcade (Bortezomib), Melphalan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Melasma
Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma.
This study would offer the participants about the knowledge of these formula in the treatment of melasma and help the investigators in incorporating and updating the management protocols in medical practice.
- Trial name
- NCT06013540
- Testing
- TAM formula (hydroquinone 2%, tretinoin 0.05% and 5% vitamin C), Kligman formula (hydroquinone 4%, fluocinolone acetonide 0.01% and tretinoin 0.05%)
- Where
- Pakistan
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Primary Intestinal Hypocholesterolemia, Abetalipoproteinemia
CArotenoid in hypoChOlesterolemia
Hypobetalipoproteinemias (HBL) represent a heterogeneous group of disorders characterized by reduced plasma levels of plasmatic lipids (mainly triglycerides, total cholesterol (TC), LDL-cholesterol (LDL-C), and apolipoprotein B…
- Conditions
- Primary Intestinal Hypocholesterolemia, Abetalipoproteinemia, Chylomicron Retention Disease
- Trial name
- CaCo (NCT05208879)
- Testing
- Characterization of carotenoid status and plasma levels of oxidative stress markers in patients (case group only), Characterization, evaluation and comparison of macular pigment density
- Where
- 3 sites in France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Covid19
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
Background: Up-to-date, there is no recognized effective treatment or vaccine for the treatment of coronavirus disease (COVID-19) that emphasize urgency around distinctive effective therapies.
- Trial name
- NCT04668469
- Testing
- Ivermectin, Hydroxychloroquine, personal protective Measures
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
Benign Paroxysmal Positional Vertigo
Benign Paroxysmal Positional Vertigo (BPPV) in Older Patients
Benign Paroxysmal Positional Vertigo (BPPV) is the most common cause of vertigo in older adults (Parham \& Kuchel, 2016). It is caused by dislodged otoconia, which fall from the utricular macula into the semicircular canals…
- Trial name
- NCT04578470
- Testing
- Vitamin D
- Volunteers
- 60 people
- Sponsor
- Changi General Hospital
Haematopoiesis
A Study to Demonstrate the Efficacy and Tolerability of Ferrous Bisglycinate Chelate in Iron Deficiency Anaemia and to Compare These With Those of Ferrous Ascorbate.
Iron deficiency anaemia (Haemoglobin, Hb < 12gm/dl) is one of India's major public health problems particularly in women. Effective control of iron deficiency anaemia decreases the incidence of fatigue, bodyache, headache, lack…
- Trial name
- NCT01160198
- Testing
- ferrous ascorbate, ferrous bisglycinate chelate 1 OD, ferrous bisglycinate chelate 2 OD
- Where
- 7 sites in India
- Volunteers
- 271 people
- Sponsor
- GlaxoSmithKline
Pregnancy, Birth Weight
Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome
Prenatal maternal micronutrient supplementation has been suggested as a means to reduce the proportion of low birth weight babies in low-income countries.
- Trial name
- NCT00168688
- Testing
- multi micronutrient supplement, MN1, MN2
- Where
- Guinea-Bissau
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Bowel Cleansing for Colonoscopy, Inadequate Bowel Preparation
Comparing Three Rescue Bowel Preparation Regimens for Colonoscopy After Failed Cleansing
The goal of this clinical trial is to learn which rescue bowel preparation works best for adults who need a repeat colonoscopy after a previous bowel preparation did not clean the bowel well enough.
- Trial name
- NCT07557173
- Testing
- Drug
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Ospedale San Pio
Elevated Blood Lead Levels
Lead Detoxifying Effects of Ascorbic Acid Among School Going Adolescents of Karachi- A Cluster Randomized Control Trial
The toxic nature of lead has been recognized ubiquitous for than 2,000 years and today it is a persistent and common environmental contaminant in most parts of the world.
- Trial name
- LDVC (NCT02745873)
- Testing
- Ascorbic Acid
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy, Protein-Energy Malnutrition
NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes
This study evaluates the intervention of Nut Fish based food, micro nutrients supplementation and pregnancy class to improve maternal and birth outcome. This is cluster randomized trial with two arms.
- Conditions
- Pregnancy, Protein-Energy Malnutrition, Anemia
- Trial name
- NCT02959125
- Testing
- NutFish Based Food Supplementation, Multiple micronutrients, Health Education in Pregnancy Class
- Where
- 2 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Semarang Health Polytechnic
Chronic Hepatitis C
Add Vitamin D With Standard of Care for Chronic Hepatitis C Patients
Standard therapy for chronic hepatitis C virus (HCV) is (Peg/RBV) combination therapy obtaining sustained virologic response (SVR) in 77% of naïve patients with genotype 1-3 Studies rarely address the issues of improving host…
- Trial name
- Addwin (NCT01439776)
- Testing
- Vit D
- Where
- 13 sites in South Korea
- Volunteers
- 180 people
- Sponsor
- Hanyang University
Scurvy
"Vitamin C Deficiency in Hospitalized Adults: Systematic Screening Vs. Traditional Judgment - a Before-and-After Observational Study"
Brief Summary of the Study The goal of this observational study is to assess the incidence of vitamin C deficiency among hospitalized adults presenting with hemorrhagic signs.
- Trial name
- NCT06876545
- Testing
- systematical screening of at risk patients based on predefined hemorrhagic criteria
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Internist.Ro
Cardiovascular Risk Factor
Vitamin C to Reduce Morning Cardiovascular Risk
This study will test the efficacy of Vitamin C to counteract morning cardiovascular (CV) risk markers in a randomized, double blind, placebo controlled crossover pilot study.
- Trial name
- NCT03290612
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Angina Pectoris
Treatment of Reperfusion Event by Vitamin C Infusion
Primary Hypothesis: Prophylactic Vitamin C Intravenous Infusion at the time of percutaneous coronary intervention (PCI) would limit the size of the infarct, assessed by measurements of cardiac biomarkers, during acute myocardial…
- Trial name
- TREVI (NCT01090895)
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
Dietary Modification
Effects of a Pre-Workout Dietary Supplement on Training Adaptations
The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.
- Trial name
- NB2 (NCT02999581)
- Testing
- C4 Extreme, C4 Extreme (without Advantra Z)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
OCD
Effect of Vitamin C Upon SSRI-treated OCD Patients
Title: Effect of Vitamin C upon Selective Serotonin Reuptake Inhibitors (SSRIs) - treated Obsessive Compulsive Disorder (OCD) patients.
- Trial name
- NCT03754647
- Testing
- Vitamin C
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Crohn Disease
Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers
This study will evaluate if the Groningen Anti-Inflammatory Diet and the ileocolonic delivery of vitamin B2, B3 and C can positively influence the course of Crohn's disease and can positively alter the gut microbiome of Crohn's…
- Trial name
- Vita-GrAID (NCT04913467)
- Testing
- Groningen Anti-Inflammatory Diet (GrAID), ColoVit capsule
- Where
- Netherlands
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Childhood Acute Promyelocytic Leukemia With PML-RARA, Myeloid Neoplasm
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia
This phase III trial is studying combination chemotherapy to see how well it works in treating young patients with newly diagnosed acute promyelocytic leukemia.
- Trial name
- NCT00866918
- Testing
- Arsenic Trioxide, Cytarabine, Diagnostic Laboratory Biomarker Analysis
- Where
- 121 sites in United States, Canada and 1 more
- Volunteers
- 106 people
- Sponsor
- Children's Oncology Group
Hyperlactatemia, Cardiac Disease
Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation
The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.
- Conditions
- Hyperlactatemia, Cardiac Disease, Bypass Complication, Valve Disease, Heart
- Trial name
- NCT04046861
- Testing
- ascorbic acid,
- Where
- Slovenia
- Volunteers
- 70 people
- Sponsor
- University Medical Centre Maribor
Pollution; Exposure
Effect of an Oral Acerola Juice Powder on Skin Beauty Parameters in Women Exposed to Environmental Stresses
The study is being conducted to evaluate the efficacy and the safety of an oral acerola-based product on skin ageing parameters.
- Trial name
- NCT07229131
- Testing
- Acerola Juice Powder 1200 mg/day, Acerola Juice Powder 600 mg/day
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Diana SAS
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