Clinical trials: Vitamin C
Vitamin C Deficiency, Acute Disease
A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency
The aim of this long-term observational study is the documentation of the use of PASCORBIN® 7.5 g in patients with vitamin C deficiency.
- Conditions
- Vitamin C Deficiency, Acute Disease, Chronic Disease
- Trial name
- NCT02422901
- Testing
- vitamin C
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Bioavailability
Comparative Bioavailability of Two Forms of Vitamin C
The purpose of this study is to compare levels of vitamin C in the blood over the 24 hour period following a single 1000 mg dose of vitamin C from ascorbic acid, calcium ascorbate and placebo.
- Trial name
- NCT01852903
- Testing
- calcium ascorbate, ascorbic acid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- NBTY, Inc.
Multiple Myeloma
Trisenox, Ascorbic Acid and Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma
This is a phase I dose escalation study to estimate the maximum tolerated dose (MTD) of the novel combination of Arsenic, Ascorbic Acid and Velcade, followed by a phase II study conducted using the MTD estimated from the phase I…
- Trial name
- AAV (NCT00590603)
- Testing
- Arsenic Trioxide, Ascorbic Acid and Bortezomib
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Micronutrient Status
Micronutrient Dose Response Study in Bangladesh
The recommended daily amounts of vitamins and minerals, referred to as micronutrients, are based on data from high income settings and for healthy populations do not fully correct nutritional deficiencies in undernourished…
- Trial name
- MiNDR (NCT06081114)
- Testing
- Micronutrient Supplement
- Where
- Bangladesh
- Volunteers
- 643 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Healthy
A Drug-drug Interaction Study of DP-R213
The purpose of this study is to learn about the effect of raloxifene on how the body absorbs and processes cholecalciferol and how cholecalciferol affects raloxifene when they are taken together.
- Trial name
- NCT02654093
- Testing
- Cholecalciferol, Raloxifene, Cholecalciferol and Raloxifene co-administration
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alvogen Korea
Bone Turnover Rate Disorder, Calcium Metabolism Disorders
Effects of Lansoprazole on Bone Turnover Markers
Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism.
- Trial name
- NCT04814316
- Testing
- Blood and urine specimens
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Obesity, Iron Deficiency
Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity
Young women living with obesity (OB) have a greater risk of developing iron deficiency. Plus, the risk of anemia and/or ID in young women living with overweight (OW) and obesity (OB) is further increased by inadequate dietary…
- Conditions
- Obesity, Iron Deficiency, Inflammation
- Trial name
- RAYON (NCT07081152)
- Testing
- Ferrous sulfate
- Where
- South Africa
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Linda Malan
Lower Urinary Tract Infection
Clinical Study to Evaluate the Efficacy of the Dietary Supplement UROMANNOSA® in Women With Recurrent Lower Urinary Tract Infections
To analyze the clinical impact of a food supplement composed of D Mannose, cranberry extract (Cran-max) and Vitamin D3 in the prevention of recurrent lower urinary tract infections (UTI)
- Trial name
- NCT04880343
- Testing
- Group (A), Group (B)
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Carmen Gonzalez Enguita
Common Cold
Symptomatic Treatment of Common Cold Symptoms
A two-arm, multicenter, randomized, double-blind, single dose placebo-controlled parallel groups study evaluating efficacy and tolerability of 800 mg Acetylsalicylic Acid (Aspirina C) in adult patients with a common cold during a…
- Trial name
- NCT01033526
- Testing
- Aspirin (Acetylsalicylic acid, BAYE4465)
- Where
- 28 sites in Italy
- Volunteers
- 388 people
- Sponsor
- Bayer
Covid19
Efficacy of Psidii Guava's Extract For COVID-19
This study was an experimental, randomized clinical trial, with a parallel design, with aims were seeing the effectiveness of extracted Psidii guava on white blood cells (WBCs) count, neutrophil, lymphocyte, monocyte…
- Trial name
- NCT04810728
- Testing
- Extract Psidii guava, Standard therapy for Covid-19 patient
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Baiturrahmah University
Functional Constipation
Effect of Probiotics on Functional Constipation in Adults
Introduction: Functional constipation is a symptom-based gastrointestinal disorder without an organic origin (eg, bowel obstruction). It has a prevalence of 14% in adults.
- Trial name
- PROBCON (NCT04437147)
- Testing
- 3 Billion UFC strains of probiotics, 8 Billion UFC strains of probiotics
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Luciane Cruz Lopes
Asthma in Children
Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children
The aim of this study will explore if the specific carbohydrate diet has an effect on asthma control in children and if it will affect the frequency, severity, and duration of asthma and thus provide it as a potential…
- Trial name
- NCT05728385
- Testing
- Modified Specific carbohydrate diet for 3 months
- Volunteers
- 60 people
- Sponsor
- Tanta University
Thin Gingival Phenotype
Injectable Platelet-Rich Fibrin and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.
This randomized split-mouth clinical trial will evaluate whether adding locally injected vitamin C to injectable platelet-rich fibrin (i-PRF) and microneedling improves gingival tissue thickness and keratinized tissue width in…
- Trial name
- NCT07848035
- Testing
- Microneedling, Injectable Platelet-Rich Fibrin (i-PRF), Vitamin C
- Where
- Yemen
- Volunteers
- 27 people
- Sponsor
- University of Science and Technology, Yemen
Osteoporosis, Vitamin C Deficiency
Link Between ASCorbemia Level and Osteoporosis
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis.
- Conditions
- Osteoporosis, Vitamin C Deficiency, Vertebral Fractures
- Trial name
- ASCO (NCT07660484)
- Testing
- Plasma vitamin C assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
CKD - Chronic Kidney Disease
Association Between Chronic Kidney Disease Stage and Circulating FGF23 Cleavage Intensity in Patients With Chronic Kidney Disease
This cross-sectional proof-of-concept study aims to investigate the relationship between chronic kidney disease (CKD) severity and circulating FGF23 (fibroblast growth factor 23) cleavage intensity estimated by the iFGF23/cFGF23…
- Trial name
- CLIFF (NCT07676526)
- Testing
- Blood sampling and biomarker assessment
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anemia in Pregnancy
Effect of Ascorbic Acid Supplementation in Pregnancy on Anemia (AAA)
A. Anemia is a common problem affecting pregnancy and can result in profound consequences to both the mother and the growing fetus. Current treatment usually includes administration of oral or IV iron, or blood transfusions.
- Trial name
- AAA (NCT03564756)
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- Fetal Medicine Foundation
Systemic Lupus Erythematosus (SLE)
Efficacy of Vitamin C Supplementation on Serum IL-6 Levels and Disease Activity in Systemic Lupus Erythematosus Patients
The study aimed to evaluate the efficacy of vitamin C supplementation compared to placebo towards IL-6 levels and disease activity with the MEX-SLEDAI score in Systemic Lupus Erythematosus (SLE) patients.
- Trial name
- NCT07071220
- Testing
- Vitamin C
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Sriwijaya
Leukemia (Both ALL and AML), Cancer of Lung
Changing Over Time of Ascorbic Acid After Chemotherapy
Rationale: Recent studies showed that ascorbic acid (AA) stimulates proliferation and maturation of T lymphocytes and NK cells. Chemotherapy results in depletion of those cells and thereby an increased infection rate.
- Conditions
- Leukemia (Both ALL and AML), Cancer of Lung, Myeloma
- Trial name
- NCT02931942
- Testing
- blood withdrawn
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Iron-deficiency
Prebiotic GOS and Lactoferrin With Iron Supplements
The ultimate goal of this research is to develop a means to safely administer iron supplements to infants in settings with a high infection burden.
- Trial name
- NCT03866837
- Testing
- Galacto-oligosaccharides, Bovine lactoferrin, Multiple micronutrient powders with 5 mg iron
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.