Clinical trials: Vitamin C
Stage I Multiple Myeloma, Stage II Multiple Myeloma
Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma
RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma, Refractory Plasma Cell Neoplasm
- Trial name
- NCT00112879
- Testing
- arsenic trioxide, ascorbic acid, dexamethasone
- Where
- United States
- Sponsor
- The Cleveland Clinic
Oligoasthenoteratozoospermia, Male Infertility
Comparative Efficacy of Antioxidants Alone Versus Combined Therapy With SERMs or FSH in Normogonadotropic Idiopathic OAT Patients: A Randomized Controlled Trial
This prospective randomized controlled trial will compare three treatment approaches for men with idiopathic oligoasthenoteratozoospermia (OAT), a condition characterized by abnormalities in sperm count, movement, and shape…
- Trial name
- NCT07862725
- Testing
- Antioxidants + Clomiphene Citrate, Antioxidants + FSH, Antioxidants Alone
- Where
- Qatar
- Volunteers
- 360 people
- Sponsor
- Hamad Medical Corporation
Gastroenteritis Escherichia Coli
Safety and Immunogenicity of Peru-15-pCTB in Healthy Adult Subjects
Enterotoxigenic Escherichia (E.) coli (ETEC) bacteria are the main cause of traveler's diarrhea and are significant pathogens affecting children and elderly individuals of developing countries.
- Trial name
- NCT00654108
- Testing
- Ciprofloxacin, Peru-15-pCTB, Sodium bicarbonate/Ascorbic Acid/Aspartame Buffer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Other Diseases or Conditions
Mother-caregivers of Children With Duchenne Muscular Dystrophy
The incidence of Duchenne Muscular Dystrophy (DMD) is approximately 1 in 3.500 male newborns. During its progression there is loss of mobility, swallowing difficulties and a significant reduction in respiratory capacity.
- Trial name
- DMDK (NCT01921374)
- Testing
- sleep parameters, Hormonal profile, Inflammatory profile
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Levy Andersen
Iron Deficiency Anemia
Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient
Given the limited long-term effectiveness of traditional weight loss methods, bariatric surgery is increasingly becoming the preferred option for sustained weight loss.
- Trial name
- NCT04268849
- Testing
- Ferumoxytol, Saline, Ferrous sulfate tablets
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Auerbach Hematology Oncology Associates P C
Cystic Fibrosis (CF)
Antioxidant Supplements in Cystic Fibrosis Children
This randomized controlled clinical trial included 60 pediatric patients with cystic fibrosis (CF) assigned randomly into two arms; Arm 1(extra care arm):received a tailored dietary plan following Mediterranean diet to cover…
- Trial name
- NCT06875050
- Testing
- Mediterranean diet, Fat soluble vitamins supplementation, Antioxidant Supplement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Rheumatoid Arthritis
Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
To compare, as a preliminary analysis, the effects of MEDI-522 versus placebo at 6 months on disease activity (ACR20) and progression of structural joint damage.
- Trial name
- NCT00069017
- Testing
- MEDI-522
- Where
- 40 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- MedImmune LLC
Vitamin C, Pneumonia, Viral
Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
2019 new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency.
- Conditions
- Vitamin C, Pneumonia, Viral, Pneumonia, Ventilator-Associated
- Trial name
- NCT04264533
- Testing
- VC, Sterile Water for Injection
- Where
- China
- Volunteers
- 56 people
- Sponsor
- ZhiYong Peng
Children With Down Syndrome
Interaction Effects of Vitamin D Supplementation and Aerobic Exercises on Balance and Physical Performance in Children With Down Syndrome
Objective: To investigate the interaction effects of vitamin D supplementation and aerobic exercises on balance control and physical performance in children with Down syndrome (DS).
- Trial name
- NCT03783338
- Testing
- Aerobic exercises and Vitamin D supplementation
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Retina, Regional Blood Flow
Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.
Oxidative stress, which refers to cellular damage caused by reactive oxygen intermediates, has been implicated in many disease processes, especially age-related disorders.
- Conditions
- Retina, Regional Blood Flow, Endotoxin, Escherichia Coli
- Trial name
- NCT00431691
- Testing
- vitamin and mineral supplement, Escherichia coli Endotoxin (LPS), 100% O2
- Where
- Austria
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypovitaminosis, Vitamin C Abnormal
Vitamin C 4 Care Homes
Older people in care homes are one of the most vulnerable groups with respect to risk, morbidity and mortality of severe coronavirus disease-2019 (COVID-19).
- Trial name
- VITA-C4CARE (NCT05122481)
- Testing
- Vitamin C
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Aberdeen
Thrombosis
Evaluation of Factors II, VII, IX, X, and Proteins C and S, Following High-dose Vitamin K Supplementation
The purpose of this study is to evaluate factor levels of the pro coagulant factors II, VII, IX, X, and the anticoagulant factors protein C and S in healthy volunteers during the intake of elevated levels of vitamin K in order to…
- Trial name
- NCT01143831
- Testing
- Vitamin K, 20mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stephan Moll, MD
Metabolic Syndrome
A 4-month Intervention of Antioxidant Supplementation in Overweight Children
In obese children, low antioxidant vitamin intake and reduced antioxidant capacity are common. Weight reduction reduces subclinical inflammation in obese subjects, and, similarly, antioxidant vitamins have been shown to reduce…
- Trial name
- NCT01316081
- Testing
- Vitamin C Vitamin E Selenvital all from Burgerstein Vitamine
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Swiss Federal Institute of Technology
Malnutrition, Dementia
Fortified Foods in Older Inpatients
Malnutrition in older inpatients is a significant problem espicially among those with dementia. A number of methods have been used to tackle this issue and oral nutritional supplements (ONS) were proven to be the most effective…
- Conditions
- Malnutrition, Dementia, Aging, Frail Elderly Syndrome
- Trial name
- NCT03176030
- Testing
- Fortified Foods
- Where
- United Kingdom
- Sponsor
- University Hospital Southampton NHS Foundation Trust
HIV Positive
Antioxidant in Patients HIV+ Supplemented With Microencapsulated of Red Pomegranate
Human immunodeficiency virus (HIV) infection continues to be a pandemic, Mexico has around 184,000 people infected by this virus.
- Trial name
- NCT03531749
- Testing
- HIV+ MRPJ, HIV+ ascorbic acid
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma del Estado de Hidalgo
Malnutrition
Observational Study at the Influence of Malnutrition on Infections
The purpose of this trial is to determine whether nutritional status has an impact on nosocomial infections. Study population are patients undergoing early neurological rehabilitation.
- Trial name
- Malnutrition (NCT01243528)
- Testing
- Laboratory values
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Marion Mertl-Roetzer
Periodontitis
Evaluation of iPRF With Vitamin C in StageII Grade A Periodontitis
Comparing the effect of using vitamin C with injectable PRF as a locally delivered adjunct to scaling and root planing versus scaling and root planing with local delivery of injectable PRF and scaling and root planing alone on…
- Trial name
- NCT05129267
- Testing
- Group B, Group C
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Glioblastoma
MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS
Glioblastoma is the most frequent primary malignant brain tumor in adults (3,000 new cases per year) and is characterized by a poor prognosis (median survival 12 months).
- Trial name
- RESECT (NCT01811121)
- Testing
- 5-aminolévulinique acid (5-ALA)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Hospices Civils de Lyon
Rhinitis, Allergic, Allergy
Effect of Vitamin C on Allergy Skin Test
This study will assess the effect of taking vitamin C on allergy skin test.
- Trial name
- NCT05810233
- Testing
- Ascorbic acid 1000mg
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Asthma
Antioxidant Therapy in Lean and Obese Asthmatics
This project will assess the effectiveness of antioxidant supplementation with common vitamins A, C, E and selenium in controlling asthma symptoms among lean and obese asthmatics.
- Trial name
- ALOA (NCT01317563)
- Testing
- Vitamins A, E, C & Selenium
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Nemours Children's Clinic
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