Clinical trials: Vitamin C
Photodamaged Skin
Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
This is a split-face, double-blind, placebo-controlled study assessing the use of a novel exfoliative serum with a chemical peel to improve photodamage in healthy female subjects between the ages of 30 and 65 years, inclusive…
- Trial name
- NCT05908825
- Testing
- Vitamin C with AHA Exfoliative Serum
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Vitamin C Deficiency
The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.
To evaluate the difference between vitamin C in the form of oral liposomes and general vitamin C in a fixed period of time in plasma and urine.
- Trial name
- NCT04886752
- Testing
- vitamin C without liposome, liposomal process A vitamin C, liposomal process B vitamin C (Double Nutri™)
- Where
- Taiwan
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Colonic Adenomas
The Impact of Split Dose of Low-volume Polyethylene Glycol on Adenoma Detection Rate
An adequate level of bowel preparation is crucial for the efficacy and safety of colonoscopy. Strong evidences suggest that bowel-preparation quality shows an inverse correlation with length of the interval between the end of…
- Trial name
- NCT02178033
- Testing
- Split dose low-volume PEG solution
- Where
- 2 sites in Italy
- Volunteers
- 514 people
- Sponsor
- Valduce Hospital
Premature Rupture of Membranes, Fetal Complications
Cranberry, Hibiscus, and Vitamin C Extracts Versus Placebo in Latency of Premature Rupture of Membranes.
The main objective of this clinical trial is to evaluate the effect of cranberry, hibiscus and vitamin C extracts supplementation on the duration of the latency of premature rupture of membranes in pregnant women between 24 and…
- Trial name
- SBERRY (NCT06788132)
- Testing
- Cranberry products
- Where
- Honduras
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Diminished Ovarian Reserve, IVF Outcomes
The Effect of VitC on IVF Outcome of DOR Patients
In the context of the accelerating aging population and the continuous decline in birth rates nationwide, delaying reproductive aging in women and protecting the fertility of women of childbearing age have become urgent issues…
- Trial name
- DORIVF-VC (NCT06794047)
- Testing
- Vitamin C
- Where
- 6 sites in China
- Volunteers
- 1,100 people
- Sponsor
- Peking University Third Hospital
Arteriovenous Fistula Occlusion
Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis
The narrowing of Dialysis Fistulae or Grafts is a near universal problem in patients with end-stage renal disease (ESRD) and requires patients to undergo repeated angioplasty or mechanical opening of the fistula.
- Trial name
- NCT03106948
- Testing
- Ascorbic Acid, Cuprimine Oral Product
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Southeast Renal Research Institute
Diarrheal Illnesses, Respiratory Illness
A Trial of Zinc and Micronutrients in Tanzanian Children
A randomized clinical trial of multiple micronutrients, zinc, zinc + micronutrients, or placebo among 2400 children born to HIV-negative Tanzanian mothers.
- Conditions
- Diarrheal Illnesses, Respiratory Illness, Growth Faltering
- Trial name
- NCT00421668
- Testing
- Zinc, Multivitamins
- Where
- Tanzania
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Stem Cell Transplant Complications, Myeloma
Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT
As the average age of individuals undergoing stem cell transplant continues to increase, challenges associated with balancing the side effects of cancer treatments while also managing other medical conditions develop.
- Conditions
- Stem Cell Transplant Complications, Myeloma, Lymphoma, Allogeneic and Autologous Stem Cell Transplant
- Trial name
- NCT04194840
- Testing
- physical therapy consult, Cognitive Assessment, Cancer Aging Research Group (CARG) assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Anemia
Evaluating of the Impact of Micronutrient Interventions Among Adolescents in Mozambique
This purpose of this study is to assess effects of iron and folic acid supplementation and multiple micronutrient supplementation on anemia status and the impact of a nutrition curriculum on diet diversity and anemia knowledge…
- Trial name
- NCT06815315
- Testing
- Multiple micronutrient supplementation, Iron Folic Acid Supplementation, Adolescent Nutrition Curriculum
- Where
- Mozambique
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- World Vision US
Kidney Stone
Influence of Obesity on Endogenous Oxalate Synthesis
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation.
- Trial name
- NCT03704350
- Testing
- controlled diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sepsis
High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
This feasibility study serves to determine if it is possible to perform a powered randomized control trial of high-dose intravenous vitamin C (ascorbic acid) as an adjunctive medication in the management of sepsis and septic…
- Trial name
- NCT04088591
- Testing
- Ascorbic Acid 500Mg/Ml Inj, Dextrose in Water
- Where
- Rwanda
- Sponsor
- Virginia Commonwealth University
Glioblastoma, GBM
A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme
This is a phase 1 (first in man) study testing the safety of adding high dose ascorbate (vitamin C) to standard radiation and chemotherapy for initial treatment of glioblastoma multiforme (GBM).
- Conditions
- Glioblastoma, GBM, Glioblastoma Multiforme
- Trial name
- NCT01752491
- Testing
- Ascorbate, Temozolomide, Radiation therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Joseph J. Cullen, MD, FACS
Tuberculosis
The Role of Vitamin D, A, and Beta Carotene in Tuberculosis Patients With Vitamin D Receptor Gene Polymorphism
Recent studies showed that vitamin D and A has an effect in improving sputum conversion in tuberculosis. This study aims to find out the effect of vitamin D 1000 IU and A 6000 IU supplementation on Tuberculosis patients with…
- Trial name
- NCT04593524
- Testing
- vitamin D 1000 IU and A 6000 IU supplementation and nutritional counseling, nutritional Counseling
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Healthy, Pharmacokinetic
A Pharmacokinetic Study of Single Oral Doses of Six Different Vitamin C Product Forms
Vitamin C (ascorbic acid) is an essential nutrient linked to many aspects of basic human physiology. It is a potent antioxidant and involved as a cofactor for many human enzymes, and its extreme deficiency can lead to a fatal…
- Trial name
- NCT06471023
- Testing
- TP1, TP2, TP3
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Vitamin D Deficiency
The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults
Many older adults do not get enough zinc, vitamin C and vitamin D, and this can be related to decreased ability to fight infection.
- Trial name
- NCT02876315
- Testing
- Redoxon VI
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Patient With an Indication of Colonoscopy for Inflammatory Bowel Disease
National Multicentric Observatory of Low Bowel Preparations in Patients With IBD
National multicentric observatory of low bowel preparations in patients with IBD
- Trial name
- CLEAN (NCT03753425)
- Testing
- Low volume bowel preparation in inflammatory bowel diseases
- Where
- France
- Volunteers
- 278 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer
Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer
This trial studies efficacy and safety of combination of vitamin C infusion with modulated electro-hyperthermia (mEHT) in treatment of non small cell lung cancer patients.Phase I of this clinical study is to find the tolerable…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- VCONSCLC (NCT02655913)
- Testing
- vitamin C, Modulated Electro-Hyperthermia (mEHT), Supportive care
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Clifford Hospital, Guangzhou, China
Mortality, Hyperhomocysteinemia
5-methyltetrahydrofolate Survival and Inflammation in ESRD Patients
A randomized prospective study was done to determine whether i.v. 5-methyltetrahydrofolate vs oral folate improved survival in ESRD patients. Homocysteine, CRP, Lp(a), albumin, folates, vitamin B6 and B12 were checked.
- Conditions
- Mortality, Hyperhomocysteinemia, Inflammation
- Trial name
- NCT00626223
- Testing
- 5-MTHF (5-methyltetrahydrofolate), folic acid
- Where
- Italy
- Volunteers
- 341 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Septic Shock
Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock.
Introduction: Septic shock leads to high morbidity and mortality in critically ill patients. Several lower-case scientific studies have supported the synergistic positive effect of vitamin C, thiamine, and hydrocortisone on…
- Trial name
- NCT06152458
- Testing
- Vitamin C
- Where
- Hungary
- Volunteers
- 43 people
- Sponsor
- University of Pecs
Atherosclerosis, Type 2 Diabetes
Vitamin C and Cardiovascular Risk
Study Goal #1: Determine the optimal oral dose of vitamin C to reduce surrogate markers of atherosclerosis (blockages in blood vessels) following the consumption of an atherogenic high fat lunch in type 2 diabetic individuals.
- Trial name
- NCT00534014
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of New Mexico
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