Clinical trials: Vitamin C
HIV Infections
The Safety and Effectiveness of Different Doses of Vitamin C in HIV-Infected Patients
This is a study to evaluate the tolerance and antiviral effect of oral vitamin C in HIV-infected.
- Trial name
- NCT00001070
- Testing
- Oral Vitamin C
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Overweight, Obesity
Anti-inflammatory Dietary Intervention in Overweight and Obese Adolescents
The number of overweight and obese children has increased in Ireland at a greater rate than worldwide trends. The poor eating patterns that drive adolescent obesity leads to an increase in the number of unhealthy inflammatory…
- Trial name
- NCT01665742
- Testing
- Supplement containing fish oil, vitamin C, alpha-tocopherol, green tea extract and lycopene
- Where
- 3 sites in Ireland
- Volunteers
- 58 people
- Sponsor
- University College Dublin
Prostatic Neoplasms
Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate Cancer
This trial represents an attempt to offer second line immunotherapy plus chemotherapy to patients who have failed prior taxane base therapy.
- Trial name
- NCT00447473
- Testing
- GM-CSF, Ketoconazole, Mitoxantrone
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The Methodist Hospital Research Institute
Out-Of-Hospital Cardiac Arrest, Postcardiac Arrest Syndrome
Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors
The mortality and neurological outcomes among out-of-hospital cardiac arrest survivors have not improved despite the medical advances. The whole body ischemia/reperfusion injuries after cardiac arrest mainly damaged the brain.
- Trial name
- NCT04921189
- Testing
- The combined supplement of Ascorbic acid, Thiamine, and Cortisol
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Asan Medical Center
Imparied Retinal Vascular Reactivity, Healthy Subjects
Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans
Oxidative stress has been implicated to play a pathogenic role in many disease processes, especially in age-related disorders such as age-related macular degeneration.
- Trial name
- NCT02221089
- Testing
- Escherichia coli Endotoxin, Retaron®
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Blood Pressure, Body Composition, Immune Function
Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial
Accordingly, the purpose of this study is to evaluate the efficacy of 1) supplementation with Synbiotic (Plexus® Triplex), 2) commercially-available Probiotic, or 3) placebo control over 30 days on the gut microbiome…
- Trial name
- GUTRCT (NCT06544915)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Gingival Hyperpigmentaion
Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
Vitamin C affect the melanocytes function not the number while diode laser cause melanocytes destruction. Although diode laser and vitamin C have proved their effectiveness in depigmentation in previous studies, there are no…
- Trial name
- NCT03252418
- Testing
- Ascorbic Acid 500 MG, diode laser
- Volunteers
- 10 people
- Sponsor
- Ain Shams University
Skin Carotenoids
Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit…
- Trial name
- NCT07513597
- Testing
- Dietary Supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Cardiovascular Diseases, Cardiovascular Risk Factor
Local Antioxidant Therapy Vasoconstriction Effects in Different Races
Cardiovascular disease (CVD) afflicts nearly one-third of the adult population with all races and ethnicities represented in CVD prevalence.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
- Trial name
- NCT03684213
- Testing
- Control (Norepinephrine), Norepinephrine + Ascorbic Acid, Norepinephrine + L-NAME
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Orthopedic Disorder, Hip Arthropathy
Iron Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation in reducing the prevalence of preoperative anemia in a cohort of 82 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04078880
- Testing
- Sucrosomial iron plus ascorbic acid
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Melasma
Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma.
This study would offer the participants about the knowledge of these formula in the treatment of melasma and help the investigators in incorporating and updating the management protocols in medical practice.
- Trial name
- NCT06013540
- Testing
- TAM formula (hydroquinone 2%, tretinoin 0.05% and 5% vitamin C), Kligman formula (hydroquinone 4%, fluocinolone acetonide 0.01% and tretinoin 0.05%)
- Where
- Pakistan
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Cardiovascular Disease, Diabetes
The Effect of Continuous Sipping of a Glucose Solution on Markers of Oxidation in Men and Women
The objective of this study is to determine the effect of reducing the rate of glucose absorption on oxidative stress after eating and to compare it with the effects of vitamin C.
- Trial name
- AOGI (NCT01440790)
- Testing
- glucose bolus, Glucose sipping, Glucose bolus plus 1g vitamin C
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Frail Elderly Syndrome
No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study
To assess the cross-sectional and 5-year prospective association between self-reported vitamin C+E dietary supplementation and markers of grip strength and frailty in community-dwelling Swiss adults.
- Trial name
- CoLaus (NCT03258970)
- Testing
- Observational cohort study
- Where
- Switzerland
- Volunteers
- 2,711 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Renal Dialysis
Effect of Whole-body Vibration Training in Patients With Renal Dialysis
To show the effect of whole-body vibration in physical performance in patients with renal dialysis.
- Trial name
- NCT07049718
- Testing
- whole body vibration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
COVID19
Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized)
Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 Mahmoud ELkazzaz(1),Tamer Haydara(2), Mohamed Abdelaal(3), Abedelaziz Elsayed(4) ,Yousry Abo-amer(5), Hesham Attia(6), Quan…
- Trial name
- Isotretinoin (NCT04353180)
- Testing
- Drug Isotretinoin (13 cis retinoic acid ) capsules+standard treatment, Isotretinoin(Aerosolized 13 cis retinoic acid) +standard treatment, Isotretinoin (13 cis retinoic acid ) capsules
- Where
- 2 sites in Egypt
- Volunteers
- 100,000 people
- Sponsor
- Kafrelsheikh University
COVID-19
Efficacy and Safety of High-dose Vitamin C Combined With Chinese Medicine Against Coronavirus Pneumonia (COVID-19)
In December 2019, coronavirus pneumonia (COVID-19) was detected in many cases in Wuhan, China. With the rapid spread of the coronavirus, cases of COVID-19 were also reported in other cities of China and other countries.
- Trial name
- NCT04664010
- Testing
- Alpha-interferon alpha, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste, fumigation/inhalation of vitamin C, Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and 5% glucose, Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and high-dose vitamin C treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xi'an International Medical Center Hospital
Uterine Leiomyoma
Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma
The investigators want to know whether the intravenous ascorbic acid would reduce the blood loss during laparoscopic myoma surgery.
- Trial name
- NCT01715597
- Testing
- ascorbic acid, Normal saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Asthma
To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children
The purpose of this project is to evaluate in a randomized clinical trial, double-blind, controlled, the effects of a dietary supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 in reducing bronchial inflammation…
- Trial name
- NCT02734446
- Testing
- Reuterin D3 drops
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Campania Luigi Vanvitelli
Pregnancy, Smoking
Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
Women who smoke during their pregnancy place their unborn child at an increased risk of health problems, including decreased lung function and possible lung diseases later in life.
- Trial name
- NCT00632476
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Oral Mucositis
Herbal Mouthrinse for Oral Mucositis Study
This study involves adults receiving radiation therapy for head and neck cancer and will test whether or not the study mouthrinse may lessen oral mucositis.
- Trial name
- OM (NCT01898091)
- Testing
- Neem Mouthrinse
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
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