Clinical trials: Vitamin C
Cataract
Antioxidants for Prevention of Cataracts Follow-up Study
Aravind Eye Hospital and the University of California, San Francisco (UCSF) Proctor Foundation collaborated on the Antioxidants for the Prevention of Cataract Study from 1997-2002.
- Trial name
- NCT01664819
- Testing
- Antioxidant
- Where
- India
- Volunteers
- 576 people
- Sponsor
- University of California, San Francisco
Dementia, Dementia, Mild
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People
We hypothesize that the antioxidant and cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols and physical activity may help prevent the age-dependent decline of mitochondrial…
- Conditions
- Dementia, Dementia, Mild, Dementia Moderate, Dementia Senile
- Trial name
- Choko-AGE (NCT05343611)
- Testing
- Combination of High Protein Diet and Physical Exercise protocol, HPP Choko, HPP/VE Choko
- Where
- 4 sites in Italy
- Volunteers
- 102 people
- Sponsor
- Massimo Venturelli, PhD
Healthy
Nutrition and Cognition in Indian Children
Nutritional deficiencies are a major problem in school children in India and have a variety of adverse effects on their cognitive development and growth, and increase susceptibility to infections.
- Trial name
- CHAMPION (NCT00467909)
- Testing
- micronutrients
- Where
- India
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. John's Research Institute
Hair Thinning, Hair Loss
A Clinical Trial to Examine the Efficacy of a Supplement to Support Healthy Hair and Skin
This is a triple-blinded, randomized, placebo-controlled clinical trial designed to evaluate the efficacy of Scale Media's Live Conscious Beyond Collagen supplement on overall hair and skin health.
- Trial name
- NCT06579742
- Testing
- Live Conscious Beyond Collagen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Scale Media Inc
Pancreatic Neoplasm
A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients
Radiation therapy improves cancer cure rates by killing cancer cells but it also contributes to long-term side effects in cancer survivors by unintentionally damaging normal organs such as the intestine.
- Trial name
- XACT-PANC-2 (NCT03541486)
- Testing
- Ascorbate, Gemcitabine, radiation therapy
- Where
- United States
- Sponsor
- Joseph J. Cullen, MD, FACS
Nutrition, Child Health
Bogota School Children Cohort
This observational study investigates the associations of nutritional indicators, biomarkers, sociodemographic conditions, and infections with child health, as well as physical, behavioral, and cognitive development.
- Conditions
- Nutrition, Child Health, Child Growth, Neurocognitive Development
- Trial name
- BoSCCo (NCT03297970)
- Where
- 2 sites in Colombia
- Volunteers
- 3,202 people
- Sponsor
- University of Michigan
Healthy
Effect of Blueberries on Vascular Function in Healthy Men
Scientific question to be addressed: To determine the effects of acute blueberry ingestion on vascular function and blood pressure in humans Hypothesis: Acute consumption of blueberry induces an improvement in blood pressure and…
- Trial name
- NCT01292954
- Testing
- Blueberries
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Reading
Non Vital Teeth
Allium Sativum Oil and Turmeric Gel as Alternative Non-vital Pulpotomy Medicaments in Primary Teeth.
The purpose of the study is to use Allium sativum oil and Turmeric gel as non-vital Pulpotomy medicaments in primary teeth by evaluating their antibacterial effect against Streptococcus mutans and Lactobacillus acidophilus.
- Trial name
- NCT05819970
- Testing
- Allium Sativum Oil, Turmeric Gel
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Macular Degeneration, Cataract
Randomized Trials of Vitamin Supplements and Eye Disease
To determine whether vitamin E supplementation reduces the risk of cataract and age-related macular degeneration (AMD) in women. To determine whether vitamin C supplementation reduces the risk of cataract and AMD in women.
- Trial name
- NCT00000161
- Testing
- Aspirin, Beta-Carotene, Vitamin C
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Fibroids
Fibroids in Women of Reproductive Age and Women Pregnancy
Dydrogesterone Multivitamin Nature treatment of fibroids in women of reproductive age and women pregnancy to lost the size fibroids.
- Trial name
- Fibroids (NCT02620345)
- Testing
- Dydrogesterone M ( case 1 ), Dydrogesterone M ( case 2 )
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.
Bioavailability of Vitamin C
Comparison of Bioavailability of Liposomal and Traditional Formulation of Vitamin C
The aim of the study was to compare the profiles of vitamin C serum concentration in healthy volunteers after the single oral administration either in a liposomal or traditional formulation.
- Trial name
- NCT05843617
- Testing
- Liposomal Vitamin C, Traditional Vitamin C
- Where
- Poland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AronPharma Sp. z o. o.
COVID - 19
Vitamin E Supplementation As Adjunctive Therapy To Lower Inflammation In COVID-19 Patients
Since the first reported case of the novel coronavirus (SARS-CoV-2) in humans at the end of 2019 in Wuhan, the virus had infected approximately 100 million individuals.
- Trial name
- VITEC (NCT07412574)
- Testing
- Patients were randomly assigned, under a double-blind design, α-Tocopherol group (n = 22)
- Where
- Mexico
- Volunteers
- 56 people
- Sponsor
- Universidad Veracruzana
Cognitive Function and Mood, Non-anaemic Iron Deficiency
Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04469010
- Testing
- Iron Bis-Glycinate Chelate and Vitamin C, Iron Bis-Glycinate Chelate
- Where
- United Kingdom
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Heliobacter Pylori Infection
Effect of Helicobacter Pylori on the Availability of Vitamin E and C
This study argues that H.pylori infection, by increasing the production of reactive oxygen species, increases the utilization of dietary antioxidants(Vit E and Vit C) that serve in quenching the free radicals, thus decreasing…
- Trial name
- NCT00303160
- Testing
- vitamin C & E supplements
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Septic Shock, Ascorbic Acid Deficiency
Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.
This is a retrospective chart review that will measure the impact on outcomes in septic shock patients who were resuscitated with a novel combination of medicines called iHAT (intravenous hydrocortisone -ascorbic acid-thiamine).
- Trial name
- NCT03913468
- Testing
- Intravenous Ascorbic Acid
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Wisconsin, Madison
Kidney Stones, Kidney Calculi
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate.
- Conditions
- Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate
- Trial name
- NCT06989320
- Testing
- Low-oxalate diet and glycolate dosing, Oral glycolate dosing, Oral 13C- ascorbic acid dosing
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sepsis, Severe, Septic Shock
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
This study has been created to compare the addition of intravenous (IV) vitamin C, thiamine, and hydrocortisone to the usual standard of care of sepsis and septic shock.
- Trial name
- ORANGES (NCT03422159)
- Testing
- Ascorbic Acid, Thiamine, Hydrocortisone
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Community Medical Center, Toms River, NJ
Type 2 Diabetes Mellitus
Effect of Vitamin D Supplementation on Hemoglobin A1c in Patients With Uncontrolled Type 2 Diabetes Mellitus
The purpose of this study is to determine if daily supplementation with 2000 International Units of Vitamin D will improve hemoglobin A1c in uncontrolled type 2 diabetics.
- Trial name
- NCT00985361
- Testing
- Vitamin D3 2000 international units daily, Vitamin C 500mg daily
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- ProMedica Health System
HIV Infections
The Safety and Effectiveness of Different Doses of Vitamin C in HIV-Infected Patients
This is a study to evaluate the tolerance and antiviral effect of oral vitamin C in HIV-infected.
- Trial name
- NCT00001070
- Testing
- Oral Vitamin C
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcopenia
Effects of L-ARGinine and Liposomal Vitamin C Supplementation On Physical Performance
In older age, reduced mobility is associated with an increased risk of reduced quality of life, disability, institutionalisation, and death, as well as increased healthcare expenditures.
- Trial name
- ARGO (NCT06865261)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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