Clinical trials: Vitamin C
Ovarian Hyperstimulation Syndrome, GnRH Antagonist
Preventive Application of GnRH Antagonist on Early OHSS
Ovarian hyperstimulation syndrome is an iatrogenic complication of controlled ovarian stimulation. Ovarian hyperstimulation syndrome prevention is a multistage process and more important than treatment.Preventive administration…
- Conditions
- Ovarian Hyperstimulation Syndrome, GnRH Antagonist, Aspirin, Vascular Endothelial Growth Factor
- Trial name
- NCT03188471
- Testing
- GnRH antagonist, aspirin
- Where
- China
- Volunteers
- 175 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Male Infertility
Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?
Many cases of male infertility are poorly understood and regarded as unexplained. Therefore, a etiological treatment for this condition can not be offered in most cases.
- Trial name
- NCT01075334
- Testing
- Porimore - A Carnitine based food supplement, Zinc and Folate Supplementation
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Major Depressive Disorder
Sumor as Adjuvant Therapy in Treatment-resistant Major Depression
Sumor is a food supplement that combines the main coenzymes of the S-Adenosyl methionine (SAMe) cycle, namely vitamins B6, B12 and folate, with SAMe and betaine.
- Trial name
- SUSCA (NCT04832178)
- Testing
- SUMOR
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Anemia
Severe Anemia Treatment Trials, Pakistan
The purpose of this study is to test the efficacy of two enhanced regimens (deworming and multivitamins) in the treatment of severe anemia in pregnant women and children 6-24 months of age in Karachi, Pakistan.
- Trial name
- NCT00116493
- Testing
- Iron-folic acid and mebendazole, Mebendazole, Multivitamins
- Where
- Pakistan
- Volunteers
- 1,009 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Collagen Synthesis, Rate of Force (RFD) Development
Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance
Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes
- Trial name
- NCT04437758
- Testing
- Collagen and Vitamin C powder mix nutritional intervention, Maximum power training exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Anemia, Iron Deficiency
Iron and Prebiotics Fortification in Kenyan Infants
Iron deficiency and anemia are health issues affecting mainly infants and women in developing countries. Iron deficiency in infancy can have long-lasting impact on cognitive and motor development of the child.
- Conditions
- Anemia, Iron Deficiency, Diarrhea, Malaria
- Trial name
- Iro'n'Pre (NCT02118402)
- Testing
- Fortified maize porridge
- Where
- Kenya
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anaplastic Astrocytoma, Anaplastic Oligodendroglioma
Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma
This phase I trial studies the side effects and best dose of ascorbic acid when given together with temozolomide in treating patients with high-grade glioma that has come back.
- Conditions
- Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Anaplastic Oligoastrocytoma, Glioblastoma
- Trial name
- NCT02168270
- Testing
- ascorbic acid, temozolomide, quality-of-life assessment
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Nebraska
Nutrient Pharmacokinetics
Vitamin Gum Pharmacokinetics
The present study will investigate the oral release and systemic pharmacokinetics of a panel water- and fat-soluble vitamins from two commercially-produced chewing gum formulations. Vitaball, Inc. (Ft.
- Trial name
- NCT03230396
- Testing
- Vitamingum Sport, Vitamingum Immunity
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Penn State University
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingival Pigmentation
Efficacy of Microneedling With Vitamin C in Performing Gingival Depigmentation
The present study will be carried to clinically evaluate the efficacy of microneedling with vitamin C in performing gingival depigmentation in comparison with conventional scalpel and diode laser.
- Trial name
- NCT07070024
- Testing
- Vitamin C, Microneedling, Diode laser
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Ovarian Reserve
Antioxidants vs. Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve
Two group of patients were selected. Group 1 represents 46 patients that received ovarian-biostimulation monthly for three months. Group 2 represents 32 patients that received antioxidant therapy daily for 3 months.
- Trial name
- NCT03621683
- Testing
- blood rich plasma platelets, Antioxidant therapy
- Where
- Venezuela
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Lucy Coleman
Asthma
To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children
The purpose of this project is to evaluate in a randomized clinical trial, double-blind, controlled, the effects of a dietary supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 in reducing bronchial inflammation…
- Trial name
- NCT02734446
- Testing
- Reuterin D3 drops
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Campania Luigi Vanvitelli
Malnutrition, Growth &Amp; Development
Effect of Maternal Supplementation From Preconception to Lactation on Child Growth and Development
The goal of this observational study is to learn about the long-term effects of maternal multiple micronutrient supplementation from preconception through to lactation on child neurodevelopment and growth in a resource-limited…
- Trial name
- NCT06641349
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Attention Deficit Hyperactivity Disorder
Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD
Approximately 1-in-20 children worldwide have Attention Deficit Hyperactivity Disorder (ADHD), a condition associated with disabling inattention, hyperactivity and impulsivity.
- Trial name
- NCT05600881
- Testing
- Methylphenidate
- Volunteers
- 35 people
- Sponsor
- University of Dublin, Trinity College
Precursor Cell Lymphoblastic Leukemia-Lymphoma, Vitamin D Deficiency
Nutrition and Body Composition in Acute Lymphoblastic Leukemia
Many adolescents with acute lymphoblastic leukemia (ALL) have been found to have low bone density by the end of treatment. This can lead to long-term suffering in survivors due to poor bone health.
- Trial name
- NCT01317940
- Testing
- Vitamin D and Calcium Citrate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Hypercholesterolemia
Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans
Limonoids are compounds found in citrus juices, seeds and peel. Some research shows that they reduce blood cholesterol and also reduce the incidence of several forms of cancer.
- Trial name
- NCT02011789
- Testing
- Citrus Limonoid Beverage
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Blood Pressure, Endothelial Dysfunction
Effect of Inorganic Nitrate Supplement on Blood Pressure
The primary purpose of this project is to assess the efficacy (effectiveness) of plant-based nitrate tablets to elevate nitric oxide in your system as measured by saliva and effect on lowering blood pressure (BP), supporting…
- Trial name
- NCT03909789
- Testing
- Plant based bioequivalent Nitrate supplementation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Child Nutritional Status, Household Dietary Diversity
Impact Evaluation of the DFID Programme to Accelerate Improved Nutrition of the Extreme Poor in Bangladesh
This is a randomized study in three areas of Bangladesh (Chars region where CLP operates, Haor region where Shiree operates, and urban slums where UPPR operates).
- Conditions
- Child Nutritional Status, Household Dietary Diversity, Maternal Nutrition Knowledge and Practices
- Trial name
- NCT02597608
- Testing
- CLP: Livelihoods, CLP: Nutrition, Shiree: Livelihoods
- Where
- Bangladesh
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
C-reactive Protein, Inflammation
Obesity, Inflammation and Oxidative Stress
The purpose of this study is to determine whether or not Vitamin C (1000 mg/day) can reduce markers of inflammation, especially C-reactive protein (CRP), in obese persons with baseline CRP greater than 1 mg/dl.
- Conditions
- C-reactive Protein, Inflammation, Obesity, Oxidative Stress
- Trial name
- NCT01028976
- Testing
- Vitamin C (ascorbic acid)
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Osteopenia or Osteoporosis
Effect of Consumption of Supplements and Enriched Olive Paste on Bone Metabolism Indices
It was a prospective randomized controlled trial. A sample of 115 apparently healthy post-menopausal women(45 -75 years of age) randomized into four groups and received supplements of Ca, Vitamin D and Mg with or without enriched…
- Trial name
- Osteoporosis (NCT06135831)
- Testing
- Functional olive paste, Calciovitmag (CDCaMg), Phosporovitmag (PDCaMg)
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of the Aegean
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