Clinical trials: Vitamin D
Pulmonary Tuberculosis
Effect of Vitamin D and Zinc Supplementation on Inflammatory Biomarkers in Pulmonary Tuberculosis Patients
This study evaluates the effect of combined Vitamin D and Zinc supplementation on inflammatory biomarkers in pulmonary tuberculosis (TB) patients during the intensive phase of treatment.
- Trial name
- NCT07899138
- Testing
- Vitamin D (Cholecalciferol ), Zinc (zinc sulphate)
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Hasanuddin University
Vitamin D Deficiency
Oral Vitamin D Substitution Weekly or Monthly and Adherence
Vitamin D deficiency (defined as 25(OH)-vitamin D serum level <50 nmol/l) is cured with supplementation by mouth. National guidelines recommend the administration of 800 IU cholecalciferol daily for an effective treatment…
- Trial name
- NCT03141593
- Testing
- Vitamin D: liquid form, start weekly, Vitamin D: liquid form, start monthly, Vitamin D: solid form, start weekly
- Where
- Switzerland
- Volunteers
- 97 people
- Sponsor
- University Hospital, Basel, Switzerland
Unspecified Adult Solid Tumor, Protocol Specific
ILX23-7553 in Treating Patients With Solid Tumors That Have Not Responded to Previous Therapy
RATIONALE: ILX23-7553 may help solid tumor cells develop into normal cells. PURPOSE: Phase I trial to study the effectiveness of ILX23-7553 in treating patients who have solid tumors that have not responded to previous therapy.
- Trial name
- NCT00004926
- Testing
- vitamin D3 analogue ILX23-7553
- Where
- 2 sites in United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypovitaminosis D
Impact of Hypovitaminosis D on Bone Disease in HIV Infected Patients
To determine the prevalence of hypovitaminosis D in HIV infected patients, and the consequences on secondary hyperparathyroidism, and bone mineral density (BMD).
- Trial name
- PuraVIHta (NCT02351284)
- Testing
- Measurement
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Jose L. Casado
Vitamin D Deficiency
Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis
Children with Cystic Fibrosis, ages greater than and equal to 36 months of age and less than or equal to 18 years of age, with a 25OHD level less than 30 ng/dL will be asked to participate in this study.
- Trial name
- NCT02613884
- Testing
- Treatment
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Hypovitaminosis D
Cholecalciferol Supplementation for Sepsis in the ICU
Sepsis in a clinical entity that occurs in patients with serious infections. Though the severity of illness may vary, every year, approximately 1.6 million Americans are treated for sepsis.
- Trial name
- CSI (NCT01896544)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Vitamin D Deficiency, Osteopenia of Prematurity
The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
The aim of this study will be to assess the effectiveness of monitored vit D supplementation in a population of preterm infants and to identify whether the proper vit D supplementation in preterm infants can reduce the incidence…
- Conditions
- Vitamin D Deficiency, Osteopenia of Prematurity, Nephrolithiasis, Metabolic Bone Disease
- Trial name
- HIDVID (NCT06199102)
- Testing
- cholecalciferol/ Devikap
- Where
- Poland
- Volunteers
- 130 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Hepatic Osteodystrophy, Liver Cirrhosis
Efficacy and Safety of Oral Ibandronate in Patients of Liver Cirrhosis With Hepatic Osteodystrophy.
Hepatic osteodystrophy(HOD) is a common but frequently overlooked complication of liver cirrhosis with a prevalence rate ranging from 13-70%. Bisphosphonates acting by inhibiting bone resorption are frequently used.
- Trial name
- NCT06022237
- Testing
- Ibandronate, Calcium, Vitamin D3
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Healthy Volunteers
Effect of Nutrition Ingredients on Microbiota Modulation
The objective of this study is to evaluate in healthy volunteers the time-dependent effect of daily consumption for four weeks of six different nutrition ingredients on relative abundance of microbial taxa in fecal samples.
- Trial name
- VitaGut (NCT03668964)
- Testing
- Vitamin B2, Vitamin C, Vitamin B2 + C
- Where
- Ireland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Type 2 Diabetes
Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids…
- Trial name
- NCT01633177
- Testing
- Vitamin D3, Omega-3 fatty acid (fish oil)
- Where
- United States
- Volunteers
- 22,220 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Osteoporosis
Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Oral Bisphosphonate (MK-0822-076)
The purpose of this study is to assess to what extent sequential treatment with odanacatib results in incremental gains in bone mineral density (BMD) over time in female participants who have received at least 3 years of…
- Trial name
- NCT01803607
- Testing
- odanacatib
- Volunteers
- 135 people
- Sponsor
- Merck Sharp & Dohme LLC
Femur Neck Fracture
Second Study of the Effect of Teriparatide on Hip Fracture Healing
The purpose of this study is to see whether teriparatide, given for 6 months versus placebo, will improve the healing of hip (femoral neck) fractures that are repaired during surgery using certain types of orthopedic screws.
- Trial name
- NCT01473602
- Testing
- Teriparatide, Calcium supplementation, Vitamin D supplementation
- Where
- 75 sites in United States, Belgium and 12 more
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company
Osteoporosis, Osteopenia
Adding Phosphorus to Osteoporosis Drug Treatment
Osteoporosis causes bones to weaken and break more easily. Calcium and phosphorus are two minerals that are essential for normal bone formation.
- Trial name
- NCT00074711
- Testing
- Calcium carbonate, Calcium Phosphate
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Creighton University
Vitamin D Deficiency, Obesity
D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children.
- Conditions
- Vitamin D Deficiency, Obesity, Diabetes Mellitus, Pre-Eclampsia
- Trial name
- D-tect (NCT03330301)
- Testing
- D-tect
- Where
- Denmark
- Volunteers
- 222,776 people
- Sponsor
- Bispebjerg Hospital
Deficiency, Vitamin D, Insulin Resistance
Vitamin D Supplementation and and Glycemic Indexes
Age affect insulin sensitivity and the metabolism, and vitamin D status was shown to have a correlation with markers of insulin resistance.
- Trial name
- NCT03478475
- Testing
- cholecalciferol (Euro-Pharm International, Canada)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Université d'Auvergne
Polycystic Ovary Syndrome
Vitamin D Levels in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome is the commonest endocrinopathy among women of reproductive age. Its worldwide prevalence has been estimated between5-10%.
- Trial name
- NCT05101811
- Testing
- Vitamin D Levels measurement using chemiluminescent assay, Vitamin D level assessment
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ghamra Military Hospital
Vitamin D Deficiency Due to Chronic Kidney Disease
Vitamin D in Dialysis Patients - Diagnostic and Therapeutic Management
The goal of this observational study is to learn about the effects of cholecalciferol administration, according to guidelines for the general population, on laboratory parameters of Chronic Kidney Disease-Mineral and Bone…
- Trial name
- NCT06571344
- Testing
- Cholecalciferol
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- Medical University of Gdansk
Paraffinoma, Granuloma, Foreign-Body
The GranStone Trial
This study will investigate whether treatment with empagliflozin or losartan can reduce the risk of kidney stone formation in patients with paraffin disease, a condition caused by the injection of paraffin oil into muscle tissue…
- Trial name
- NCT07828002
- Testing
- empagliflozin (Jardiance) 25 mg, Losartan 100 mg
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Martin Blomberg Jensen
Pneumonia
Vitamin D Supplementation and Respiratory Index of Severity in Children (RISC) in Pneumonia
Childhood deaths from pneumonia is almost 2000 times higher in developing countries than in developed countries. In 1970, pneumonia was responsible for 9% of all deaths in children under 5 years. This rate was 2% in 2007.
- Trial name
- NCT02936895
- Testing
- Vitamin D3
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Multi Organ Failure, Acute Kidney Injury
Serum Vitamin D Levels in Critically Ill Patients Undergoing Regional Citrate Anticoagulation CRRT
Several studies point at a potential relationship between vitamin D deficiency and worse outcome in critically ill patients admitted to the intensive care unit.
- Trial name
- VitDcrrt (NCT02414386)
- Testing
- biospecimen retention
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu