Clinical trials: Water
Effect of High Altitude
Effect of High Altitude Exposure, Acclimatization and Re-exposure on Lung Water Content by Ultrasound
Prospective interventional trial in lowlanders evaluating effect of acute exposure, acclimatization and re-exposure to high altitude.
- Trial name
- NCT02760186
- Testing
- Altitude Exposure
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Iron Deficiency Anemia
Oral Iron Substitution for Orthopedic Surgery
The aim of this pilot study is to investigate an 4 weeks period of oral iron substitution in the course of Patient Blood Management in preparation for orthopedic surgery.
- Trial name
- NCT02973074
- Testing
- OLEOvital
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Kepler University Hospital
Urinary Bladder, Neurogenic, Neuropathic Bladder
Detrusor Contraction During the Ice-water-test
In this randomized, double-blind clinical trial including patients with a neurogenic lower urinary tract dysfunction undergoing urodynamic investigation at the Spinal Cord Injury Center, Balgrist University Hospital, Zürich, we…
- Trial name
- NCT01773213
- Testing
- Ice-water-test
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Balgrist University Hospital
Rheumatoid Arthritis - Rheumatism
Application of Warm Water and Warm Salt Water to Patients With Rheumatoid Arthritis
This pretest-posttest randomized controlled study aimed to determine the effect of warm salt water and warm water bath applied to the hands and feet on pain, fatigue, sleep quality, and functional capacity in patients with…
- Trial name
- NCT05888220
- Testing
- warm salt water bath
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Dentin Sensitivity, Hypersensitivity Dentin
Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment
This study aims to evaluate the longevity and efficacy of two products potassium oxalate-basedin two concentrations, 10% and 5%, by triple randomized blind clinical trial (split-mouth) .
- Conditions
- Dentin Sensitivity, Hypersensitivity Dentin, Dentine Hypersensitivity, Dentin Hypersensitivity
- Trial name
- NCT03083496
- Testing
- Potassium Oxalate 5%, Potassium Oxalate 10%
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Uberlandia
Sepsis
Mild Therapeutic Hypothermia During Severe Sepsis
Objectives: to evaluate the feasibility, the safety and the effects on physiological parameters of mild therapeutic hypothermia during septic shock. Design: a randomized, controlled, pilot physiological study.
- Trial name
- NCT01069146
- Testing
- Mild therapeutic hypothermia induction
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Heart Failure, Congestive
A Phase I Study to Assess the Pharmacokinetics of GSK2798745 Tablets
GSK2798745 is being developed as a novel therapeutic intervention for the treatment of pulmonary edema associated with heart failure (HF) and is currently under investigation in the form of a compounded capsule.
- Trial name
- NCT02925546
- Testing
- GSK2798745 Micronized API without SLS and hypermellose (Tablet A), GSK2798745 Micronized API with SLS and hypermellose (Tablet B), GSK2798745 milled API without SLS and hypermellose (Tablet C)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypertension
Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension
A comparison study of two combination drugs, amlodipine/benazepril and benazepril/HCTZ to evaluate the effectiveness of the combination on reducing heart disease and death in a high risk hypertensive population.
- Trial name
- ACCOMPLISH (NCT00170950)
- Testing
- Benazepril/amlodipine 20/5 mg - Dose Level 1 from Day 1 to Month 1, Benazepril/amlodipine 40/5 mg - Dose Level 2 from Month 1 to Month 2, Benazepril/amlodipine 40/10 mg - Dose Level 3 from Month 2 to Month 3 and thereafter
- Where
- 5 sites in United States, Denmark and 3 more
- Volunteers
- 11,506 people
- Sponsor
- Novartis
Alzheimer Disease
Efficacy, Safety of Astragalus Membranaceus in Mild-to-Moderate Alzheimer's Disease
Alzheimer's disease (AD), the most common cause of dementia, is characterized by cognitive impairment, mental and behavioural abnormalities, and social dysfunction.
- Trial name
- NCT06694597
- Testing
- Astragalus Membranaceus Root
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Medical University Union Hospital
Pneumonia
Comparative Effects of Blow Bottle and Acapella Along With Diaphragmatic Breathing in Patients With Pneumonia
Pneumonia is the inflammation of lung parenchyma involving lungs alveoli and is a leading cause of lower respiratory tract infections and deaths around the globe and the number rises greatly after the Covid-19 pandemic.
- Trial name
- NCT06460610
- Testing
- Blow Bottle technique, Acapella along with Diaphragmatic Breathing
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Metastatic Prostate Cancer
The Role of Ga68-PSMA-11 PET Imaging in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
This is an open-label single arm clinical trial, Plan to enroll approximately a total of 43 evaluable subjects. According to the estimated missing rate 15%, the sample size in this study is 51.
- Trial name
- NCT03977610
- Testing
- Ga-68 PSMA ligand
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Chang Gung Memorial Hospital
Blood Loss, Surgical
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods.
- Trial name
- NCT07721623
- Testing
- Carbetocin
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19)
A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir
Healthy adults will be enrolled into this open-label, Phase 1 research study. Participants will spend about 9 nights and 10 days in the clinical research unit (CRU) and the total time in the study will be about 11 weeks.
- Conditions
- Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19), COVID-19 (Coronavirus Disease 2019), Upper Respiratory Tract Infections
- Trial name
- NCT07552779
- Testing
- Ibuzatrelvir co-process API film coated tablet, Ibuzatrelvir filmcoated tablet
- Where
- Belgium
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Glycemic and Insulinemic Responses of Low-Carbohydrate Snack Foods
The aim of this study is develop recipes containing CHO less than ICR, prepare new snacks alternatives that could be consumed without need for additional insulin doses, and evaluate the glycemic and insulinemic responses of these…
- Trial name
- NCT04175496
- Testing
- Blueberry Cake, Snacks with Cheese, Spicy Crackers
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Epistaxis
Hot Water Irrigation in Posterior Epistaxis
This study was aimed to assess the efficacy and factors affecting the success of hot water irrigation in management of posterior epistaxis.
- Trial name
- NCT04151888
- Testing
- Foley catheter
- Volunteers
- 20 people
- Sponsor
- Assiut University
Diabetes Mellitus Type II
Effect of Calcium Polycarbophil on Type II Diabetes Mellitus Control: a Randomized Double-blind Study
The purpose of this study is to determine whether a form of fiber if effective in improving the treatment of type 2 diabetes. Measurements of other possible medical benefits will include blood pressure, cholesterol, weight, and…
- Trial name
- NCT01252524
- Testing
- Calcium polycarbophil
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- East Carolina University
Concussion, Mild
Pro-2-Cool Pivotal Trial II
This study is being conducted to determine the clinical safety and efficacy of Pro-2-Cool mediated head and neck cooling when applied after concussion and improved symptomatology among adolescent athletes as quantified by…
- Trial name
- NCT06929923
- Testing
- Pro2Cool Device
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- TecTraum Inc.
Neonatal Diseases and Abnormalities, Neonatal Mortality
Melatonin for Pulmonary Hypertension in Full Term Neonates
Published evidence has provided a possible role of melatonin and the treatment of pulmonary hypertension through its strong antioxidant properties and improving vascular function in animals.
- Conditions
- Neonatal Diseases and Abnormalities, Neonatal Mortality, Pulmonary Arterial Hypertension, Pulmonary Arterial Hypertension, Children
- Trial name
- NCT06685679
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Symbiotic, Uremic Toxins
Alterations of Gut Derived Uremic Toxins and Microbiome Metabolites by Multispecies Synbiotic
Patients with chronic kidney disease (CKD) undergoing maintenance hemodialysis frequently exhibit significant gut microbiota dysbiosis and increased intestinal permeability.
- Conditions
- Symbiotic, Uremic Toxins, Gut -Microbiota
- Trial name
- NCT07443280
- Testing
- Multispecies Synbiotic Supplementation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
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