Clinical trials: Water, completed
Pulmonary Arterial Hypertension
Effect of Food on BIA 5-1058
The aim of this study is to investigate the effect of food on the pharmacokinetic (PK) profile of BIA 5-1058 after a single dose in healthy subjects.
- Trial name
- NCT04991155
- Testing
- BIA 5-1058
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
NAFLD
Healthy Eating Through Reduction Of Excess Sugar
The purpose of the study is to determine the effect of dietary sugar reduction in obese children and examine whether there are differential effects based on genotype of a single amino acid substitution in the PNPLA3 gene that is…
- Trial name
- HEROES (NCT02948647)
- Testing
- Standard of care plus sugar-reduction education
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- University of Southern California
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Endothelial Dysfunction
Effect of Chlorogenic Acids on the Human Vasculature
This study evaluates effects of different doses of chlorogenic acids on vascular health.
- Trial name
- NCT03520452
- Testing
- Green coffee extract
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
TNBC - Triple-Negative Breast Cancer, Breast Cancer
Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC)
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of trilaciclib versus placebo administered prior to gemcitabine and carboplatin in patients receiving first- or…
- Trial name
- PRESERVE 2 (NCT04799249)
- Testing
- Trilaciclib, Gemcitabine, Carboplatin
- Where
- 71 sites in United States, Australia and 9 more
- Volunteers
- 194 people
- Sponsor
- G1 Therapeutics, Inc.
End Stage Renal Disease
Pharmacokinetics of Triferic (Ferric Pyrophosphate Citrate) Administered Intravenously to Healthy Adult Volunteers
This is a Phase 1, open-label, three-period sequential dosing study being conducted to determine the pharmacokinetics of Triferic iron administered intravenously (IV) to healthy adults.
- Trial name
- RMFPC-12 (NCT02636049)
- Testing
- Triferic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Stress Reaction, Stress, Psychological
Mind-Body Modalities for Nursing Students
Background: Nursing students around the world can experience tremendous stress due to their multi-faceted responsibilities. Stress is related to negative health and academic outcomes.
- Conditions
- Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT05172804
- Testing
- Progressive muscle relaxation, Guided Imagery, Mindfulness Meditation
- Where
- Jordan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Constipation
Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation
This study intends to evaluate the effects of three prebiotic solid beverages (mainly dietary fiber and prebiotics) and one probiotic solid beverage on the laxative effect of patients with functional constipation through…
- Trial name
- NCT04667884
- Testing
- Prebiotics or Probiotics
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xi'an Jiaotong University
Hip Surgery Corrective
Fluid and Nutrition in Elective Hip Surgery
The purpose of this study is to determine whether fluid or glucose administration before hip replacement surgery minimizes postoperative muscle breakdown (catabolism), fatigue and disturbances in carbohydrate metabolism.
- Trial name
- NCT01211184
- Testing
- Water administration, carbohydrate drink, Fasting.
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
Sleep Quality, Comfort
The Effects of Receiving Warm Footbath With Lavender Essential Oil on Sleep and Comfort
Purposes: Describe the background information and clinical characteristics of respirator-dependent patients, verify the sleep and comfort effects of respirator-dependent patients whether or not they receive a lavender essential…
- Trial name
- NCT06380933
- Testing
- experimental group
- Where
- Taiwan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Obesity, Diabetes
Innovation of Breakfast Cereals and Snacks for Control of Appetite and Post-Prandial Glycemia
The goal of the proposed research is to investigate the effects of novel snack products differing in macronutrient composition, fibre and sugar content on post-prandial glycemia and short-term appetite control in healthy adults.
- Trial name
- NCT02465021
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Health Behavior
Comparison of Interventions to Promote Health in Workers
The goal of this research was to investigate different intervention strategies in the workplace and their impact on quality of life of workers from companies in the city of Londrina, Parana, Brazil.
- Trial name
- NCT01484834
- Testing
- Exercise and Education, Exercise, Educational Intervention
- Where
- Brazil
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Healthy Volunteers
A Combined SAD and MAD Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of IFB-088
This is the first study of single and multiple doses of IFB-088 in human subjects. The current study is designed to assess in the first part, the safety, tolerability, plasma and urine pharmacokinetics (PK) of single oral doses…
- Trial name
- NCT03610334
- Testing
- IFB-088 (2.5-60.0mg) oral capsule, IFB-088 (15.0-50.0mg) oral capsule
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- InFlectis BioScience
Prematurity, Necrotizing Enterocolitis
Collaborative Research Group for Necrotizing Enterocolitis
This proposal will test the hypothesis that synthesis and catabolism of epidermal growth factor (EGF), the genotype of the EGF gene, and the microbiome interact to influence EGF expression in infants at risk for necrotizing…
- Trial name
- NCT00828451
- Testing
- [5,5,5-2H3]leucine (stable isotope labeled leucine)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Washington University School of Medicine
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Cervical Cancer
A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Objective: The main objective of this study is to verify the level of comfort for patients and the degree of cervical visibility for health providers using a novel smart speculum compared to the standard speculum.
- Trial name
- NCT06359431
- Testing
- Novel Smart Speculum, Standard speculum
- Where
- Cameroon
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GICMED
Obesity
Metabolism of Obese Women Under Exercise and Recovery Hypoxia
Obesity is characterized as a low-grade systemic inflammatory disease, which changes several pro-and anti-inflammatory cytokines.
- Trial name
- NCT05380830
- Testing
- Tied deep-Water Running
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Epilepsy
Safety and Pharmacokinetics Study of E2007 to Treat Partial and Generalised Seizures in People With Epilepsy
The objectives of this study were to assess the tolerability and safety of E2007 in patients with refractory partial or generalised seizures and to assess the pharmacokinetics of E2007 in epileptic patients receiving at least one…
- Trial name
- NCT03780907
- Testing
- E2007
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Eisai Co., Ltd.
Healthy
The Effects of a2 Infant Formula on Growth and Tolerance in Healthy Term Infants
This is a randomized, open-label, prospective study to evaluate the nutritive effects of an a2 infant formula on growth and tolerance in healthy term infants.
- Trial name
- NCT06256094
- Testing
- a2 Platinum Premium Infant Formula Stage 1, Frisolac Infant Formula Stage 1 (Dutch Edition)
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
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