Clinical trials: Water, completed
Chronic Periodontitis
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
The study proposes to assess the effect of multiple applications of antimicrobial Photodynamic Therapy (aPDT) as an adjunct to non-surgical periodontal treatment (nsPT) in smokers without use of antibiotics.
- Trial name
- NCT03039244
- Testing
- Photodynamic therapy, Control Group, Diode Laser
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy Volunteers
A Study of Relative Bioavailability and Food Effect Study of Cobimetinib in Healthy Participants
This study will be an open-label, randomized, 3-way, 6-sequence crossover study in healthy participants for determining the relative bioavailability of the tablet formulation to the capsule formulation and the effect of food on…
- Trial name
- NCT01249131
- Testing
- Cobimetinib
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Acute Ischemic Stroke
Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke
Stroke is a major cause of death and long-term disability in the developed world. While t-PA and mechanical thrombectomy have been shown to decrease disability in properly selected patients, many patients are left with lifelong…
- Trial name
- NCT04918719
- Testing
- Acetylcysteine, Dextrose in Water
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Diabete Mellitus, Diabetic Nephropathy
Nephroprotective Effects of Fig (Ficus Carica L.) Leaf Supplementation
Diabetic nephropathy is the result of diabetes complications. Excessive blood glucose levels affect several organs which include liver, heart, and kidneys.The aim of this study is to use the nephroprotective and metabolic effects…
- Trial name
- NCT07718880
- Testing
- Control group, Intervention group
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Task Performance and Analysis
Comparative Effects of Post-exercise Ingestion of a High or Low Molecular Weight Solution on Resistance Exercise Performance
This study sought to examine differences in resistance exercise performance, as measured by the kinetic and kinematic profile during multiple sets of the back squat exercise, following ingestion of high or low molecular weight…
- Trial name
- NCT02778373
- Testing
- Vitargo ®, Swecarb AB, Karlskrona, Sweden, DE15 maltodextrin, Matrin® M160, Grain Processing Corporation, Muscatine, IA
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Idiopathic Pulmonary Fibrosis
A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
This study is open to adults with a lung disease called Idiopathic Pulmonary Fibrosis (IPF). People can join the study if they are 40 years or older.
- Trial name
- NCT05321069
- Testing
- BI 1015550
- Where
- 334 sites in United States, Argentina and 35 more
- Volunteers
- 1,177 people
- Sponsor
- Boehringer Ingelheim
Opioid Use
Safely Disposing of Surplus Prescription Opioids
This study evaluates two interventions intended to increase the safe disposal of leftover prescription opioids, compared to no intervention.
- Trial name
- DISPOSE (NCT03855241)
- Testing
- Informational Sheet, DisposeRx Drug Disposal kit
- Where
- United States
- Volunteers
- 499 people
- Sponsor
- Johns Hopkins University
Spinal Cord Injury
Comparison of Lokomat and Aquatic Exercise for Individuals With Chronic Incomplete Spinal Cord Injury
Many people with spinal cord injury (SCI) hold some ability to move their leg muscles, and are therefore considered to demonstrate a motor incomplete injury.
- Trial name
- NCT01407354
- Testing
- Lokomat treadmill training, Aquatic exercise therapy
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Maryland, Baltimore
Cystic Fibrosis
A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis
The purpose of this study is to determine the safety and local tolerability of multiple dose administration of inhaled OligoG in CF subjects.
- Trial name
- OligoG (NCT01465529)
- Testing
- OligoG CF-5/20, Saline
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 26 people
- Sponsor
- AlgiPharma AS
Leukemia, Acute Lymphocytic Leukemia
RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia
The goal of Phase I of this clinical research study is to find the highest tolerable dose of RAD001 (everolimus) when given in combination with the standard chemotherapy regimens to patients with ALL.
- Trial name
- NCT00968253
- Testing
- Everolimus (RAD001), Cyclophosphamide, Vincristine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- M.D. Anderson Cancer Center
Pharmacokinetic
A Clinical Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Cebranopadol
The objective of this study was to evaluate the pharmacokinetics (PK), safety and tolerability profile of cebranopadol (GRT6005) in patients with varying degree of renal impairment and participants with normal renal function…
- Trial name
- NCT03882762
- Testing
- Cebranopadol 200 μg tablet
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Alcohol Drinking, Binge Drinking
Alcohol, Behavior, and Brain Imaging
To evaluate the relationship of extraversion to both the acute subjective and behavioral effects of alcohol, and the neural reactivity to the anticipation of reward.
- Conditions
- Alcohol Drinking, Binge Drinking, Drinking Behavior, Substance-Related Disorders
- Trial name
- (DARC) (NCT03930446)
- Testing
- Ethanol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Spatial Neglect, Dysphagia
Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia
The purpose of this study is to examine how stroke can alter arousal, alertness, neglect and dysphagia, and whether a medication, modafinil, can improve arousal.
- Trial name
- NCT01085903
- Testing
- Modafinil, Baseline, CPS
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Arkansas
Diabetes Mellitus, Diabetes, Gestational
Randomized Clinical Trial of Lifestyle Interventions to Prevent Diabetes in Women With Previous Gestational Diabetes
Randomized trial aiming to investigate the effectiveness of a lifestyle intervention program implemented within the first year after a pregnancy complicated by gestational diabetes (GDM), in delaying or preventing the development…
- Trial name
- LINDA-Brasil (NCT02327286)
- Testing
- Promote and support healthy behaviors
- Where
- 3 sites in Brazil
- Volunteers
- 473 people
- Sponsor
- Federal University of Rio Grande do Sul
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Demonstrate That the Postprandial Glucose Response of FiberSMART is Consistent With the Response Expected From a Dietary Fiber
Effect of Tapioca-based FiberSMART® Compared to a Glucose Challenge or Water Control on Postprandial Glycemia in Healthy Subjects: An Acute Randomized Controlled Trial
The goal of this clinical trial is to learn whether a novel tapioca-based soluble fiber, FiberSMART®, affects blood glucose levels after consumption in healthy adult volunteers.
- Trial name
- NCT07075822
- Testing
- 20g of FiberSMART®, 20g of Dextose, Water Control
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Insulin Sensitivity
Acute Effects of an Oral Fat Load on Skeletal Muscle and Hepatic Insulin Sensitivity
The development of type 2 diabetes is based on a combination of insulin resistance and beta cell dysfunction. In the last years, elevated FFA were recognized as a key players in the pathogenesis of insulin resistance and type 2…
- Trial name
- FLAME (NCT01736202)
- Testing
- fat orally
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
GI Cancer, Nutritional Deficiency
Mobile APP Utilization for Enhanced Post-Operative Nutritional Recovery
This study is to assess the usability and acceptability of a digital food consumption diary as part of the perioperative management of gastrointestinal oncology patients and to evaluate the impact of a digital food diary on…
- Trial name
- NCT04091165
- Testing
- My Plate Calorie Tracker
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cardiovascular Disease
The Effects of Peanuts and Peanut Products on Glucose Control and Vascular Function
Pilot study data have demonstrated that peanuts ameliorate the postprandial glucose and insulin response when incorporated into an acute high fat/high glucose meal.
- Trial name
- NCT01405300
- Testing
- Control, Peanut
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy
A Twelve Week Study of Supervised Mouth Rinse and Flossing
The purpose of this study is to evaluate the efficacy of twice daily alcohol containing essential oil mouth rinse and brushing versus dental flossing and brushing under once daily supervision for the prevention and reduction of…
- Trial name
- NCT04696536
- Testing
- Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Referenced Toothbrush, 5% Hydroalcohol Mouth Rinse
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
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