Clinical trials: Water
Pediculus Humanus Capitis (Head Lice)
Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation
This is a Phase 2 single center study designed to compare the safety, local tolerability, and efficacy of 3 strengths of ivermectin treatment conditioner to placebo.
- Trial name
- NCT00857948
- Testing
- ivermectin treatment conditioner
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Topaz Pharmaceuticals Inc
Kidney Transplantation, Renal Transplantation
12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients
This study was designed to evaluate the renal function comparing Certican based immunosuppressive regimens with two different CNIs (Tacrolimus or Cyclosporin A) versus a standard treatment with Mycophenolic Acid and Tacrolimus in…
- Trial name
- ATHENA (NCT01843348)
- Testing
- Everolimus, Tacrolimus, Cyclosporin A
- Where
- 27 sites in France, Germany
- Volunteers
- 612 people
- Sponsor
- Novartis Pharmaceuticals
Extreme Immaturity
Sodium Supplementation and Growth in Very Low Birth Weight Infants
Adequate growth during the neonatal period is critical for optimal long term outcomes. Despite maximal calorie intake, sixty percent of very low birth weight infants still fail to thrive suggesting that factors other than total…
- Trial name
- SSALT (NCT01795638)
- Testing
- Sodium chloride
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Inflammation
Enhancing Adaptations to Exercise
Researchers are trying to understand how chronic inflammation affects muscle function and responses to exercise.They are also trying to determine if suppressing chronic inflammation using omega-3 fatty acids (n3-PUFA) restores…
- Trial name
- NCT03350906
- Testing
- n3-PUFA, Biopsy, Body Composition Scan
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dentinal Hypersensitivity, Dental Pain
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
A randomized, controlled, double blind exploratory study to explore the effects of two different potassium nitrate concentrations and water on exposed dentine in reducing dentinal hypersensitivity.
- Trial name
- NCT01587950
- Testing
- Potassium Nitrate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Pain
Vapocoolant Spray Used Prior to Intravenous (IV) Insertions
The primary purpose of this study is to determine if by offering a vapocoolant (cold spray) to hospital outpatients prior to an intravenous catheter (IV) insertion will increase patient satisfaction of IV insertion as well as…
- Trial name
- NCT03054740
- Testing
- Gebauer Ethyl Chloride, Nature's Tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aultman Health Foundation
Stomatitis, Oral Mucositis
Efficacy of SNX-1012 in the Treatment of Oral Mucositis
Oral mucositis (OM) is a common and debilitating toxicity induced by many chemotherapy (CT) regimens and by radiation to the head and neck.
- Trial name
- NCT00385515
- Testing
- SNX-1012 (meclocycline sulfosalicylate)
- Where
- 27 sites in United States, India
- Volunteers
- 81 people
- Sponsor
- Mucosal Therapeutics
Healthy
A Study to Compare Two Different Formulations of Lasmiditan in Healthy Participants
The main purpose of this study is to compare the amount of lasmiditan that gets into the blood stream and how long it takes the body to get rid of it, when given as a oral-disintegrating (OD) tablet compared to immediate-release…
- Trial name
- NCT04881747
- Testing
- Lasmiditan
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy Volunteers
Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a novel calcium carbonate-vitamin D3 chewable tablet formulation (calcium 500 milligrams (mg) and vitamin D3 1000 International Units…
- Trial name
- NCT02338713
- Testing
- Calcichew D3, Noncarbonated Water
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Takeda
Spinal Cord Injury Cervical
Access-H20 Faucet for Spinal Cord Injury
The Phase I SBIR objective is to design, develop \& demonstrate feasibility of Access-H2OTM, a sensor driven smart faucet to enable and empower independent drinking and grooming for individuals impacted by spinal cord injury…
- Trial name
- NCT06159946
- Testing
- Access-H2O faucet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
HIV
Condom Performance in a Longitudinal Enhanced Assessment of User Experiences
This study will enroll 252 men who have sex with men (MSM) and 252 men who have sex with women (MSW) in a double-blind, three-way randomized crossover trial with conditions of fitted, thin, and standard condoms.
- Trial name
- C-PLEASURE (NCT02753842)
- Testing
- 5 Fitted Condoms, 5 Thin Condoms, 5 Standard Condoms
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Global Protection Corp.
Radiotherapy Induced Mucositis, Head and Neck Cancer
A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer
The primary hypothesis of this study is that regular topical oral application of Manuka Honey will reduce the severity and duration of oral mucositis in patients who are undergoing mucotoxic radiation therapy for cancer treatment.
- Trial name
- NCT00615420
- Testing
- manuka honey
- Where
- 2 sites in Canada
- Volunteers
- 106 people
- Sponsor
- British Columbia Cancer Agency
Plantar Fascitis
Photobiomodulation for Plantar Fasciitis
BACKGROUND: Plantar fasciitis, a degenerative injury of the connective tissue in the foot, results in pain-related disability in Service Members and beneficiaries and contributes to decreased physical activity and excessive…
- Trial name
- NCT03015116
- Testing
- Stretching, Cryotherapy, Photobiomodulation Low Power
- Where
- Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Landstuhl Regional Medical Center
Asthma
Timely Intravenous Magnesium for Asthma in Children
Many children currently being hospitalized with severe asthma could potentially avoid hospitalization and be sent home if their treatment in the emergency department was more effective.
- Trial name
- IMPACT-ED (NCT05166811)
- Testing
- Magnesium Sulfate, Heptahydrate, 0.9% saline
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of Utah
Gastric Cancer
Prospective Randomized Trial Comparing Gastrectomy, Metastasectomy Plus Systemic Therapy Versus Systemic Therapy Alone: GYMSSA Trial
Background: Gastric (stomach) cancer is a rare cancer. In most cases, by the time it has been diagnosed it has spread to other organs in the body and the chance of a cure is very small.
- Trial name
- NCT00941655
- Testing
- Oxaliplatin, Irinotecan, 5-Fluorouracil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute (NCI)
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Healthy Subjects
Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects
This was a single-center study using induced blood stage malaria infection to characterize the activity of ACT-451840 against early Plasmodium falciparum blood stage infection
- Trial name
- NCT02223871
- Testing
- ACT-451840:, Plasmodium falciparum-infected human erythrocytes:, Artemether 20 mg and lumefantrine 120mg combination tablet:
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Incontinence-associated Dermatitis
Evaluation of Skin Cleansers and Skin Protectants in Management of Incontinence-associated Dermatitis
The aim of this study is to evaluate the efficacy of two different skin care regimens (3M Cavilon Advanced Skin Protectant with 3M No-Rinse Cleanser and Coloplast Conveen Critic Barrier with Easi-Cleanser) against standard care…
- Trial name
- NCT04625426
- Testing
- 3M Cavilon No-Rinse Skin Cleanser and 3M Cavilon Advanced Skin Protectant, Conveen EasiCleanse and Conveen Critic Barrier, Standard cleansing and Conveen Critic Barrier
- Where
- Singapore
- Volunteers
- 86 people
- Sponsor
- Tan Tock Seng Hospital
Glucose Metabolism, High Altitude
High Altitude and Exogenous Carbohydrate Oxidation
Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders.
- Trial name
- NCT03851744
- Testing
- Sea Level, High Altitude
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
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