Clinical trials: Water
Nutritional Stunting, Feeding Behavior
Suaahara Impact Evaluation: End-line Survey
Suaahara's primary aim is to reduce the prevalence of stunting, wasting, and underweight among children under 5 years of age and to reduce the prevalence of anemia among women of reproductive age and children 6-59 months of age.
- Trial name
- NCT05448287
- Testing
- Health and family planning, Nutrition, Agriculture and homestead food production
- Where
- Nepal
- Volunteers
- 2,480 people
- Sponsor
- University of South Carolina
Pain, Postoperative, Root Canal Infection
Effectiveness of GentleWave System in Endodontic Treatment
This study aims to evaluate the efficacy of the GentleWave® System compared to conventional methods in reducing postoperative pain in patients with necrotic pulp or requiring endodontic retreatment.
- Conditions
- Pain, Postoperative, Root Canal Infection, Endodontically Treated Teeth
- Trial name
- NCT06518304
- Testing
- GentleWave, Conventional Protocol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Atrial Flutter
ICE Based Atrial Flutter Ablation Vs Conventional Fluoroscopy/Anatomical Mapping Based Ablation - ICE Flutter Study
Intracardiac echocardiography (ICE), has been an essential component of Radiofrequency (RF) ablations for AF given its association with decreased fluoroscopy time and complication rates, and therefore it is logical that this can…
- Trial name
- NCT05229848
- Testing
- 3D electroanatomical mapping alone guided CTI ablation, ICE plus 3D electroanatomical mapping guided CTI ablation
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Corona Virus Infection
Trial of Treatments for COVID-19 in Hospitalized Adults
DisCoVeRy is a randomized controlled trial among adults (≥18-year-old) hospitalized for COVID-19. This study is an adaptive, randomized, open or blinded, depending on the drug to be evaluated, clinical trial to evaluate the…
- Trial name
- DisCoVeRy (NCT04315948)
- Testing
- Remdesivir, Lopinavir/ritonavir, Interferon Beta-1A
- Where
- 62 sites in Austria, Belgium and 5 more
- Volunteers
- 1,552 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Low Anterior Resection Syndrome, Rectal Cancer
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer, Insomnia, Sleep Disorder
- Trial name
- TraLARS (NCT06222255)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Type2 Diabetes
A Study to Investigate the Bioequivalence Test of DA-1229_01(A) at Fed State
A study demonstrates the bioequivalence of DA-1229_01(A) at Fed State when compared with Sugamet sustained-release(SR) Tab 5/1000mg® in healthy adults
- Trial name
- NCT03944200
- Testing
- DA-1229_01(A), Sugamet SR Tab 5/1000mg®, Sugamet SR Tab 5/1000mg®, DA-1229_01(A)
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Pain
Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture
The objective of this study is to determine the relative efficacy of sucrose, liposomal lidocaine, and sucrose plus liposomal lidocaine, on reducing pain during venipuncture in newborn infants.
- Trial name
- NCT00519207
- Testing
- Lidocaine, 24% Sucrose Solution
- Where
- 2 sites in Canada
- Volunteers
- 330 people
- Sponsor
- The Hospital for Sick Children
Anthrax
Anthrax AV7909 Boost Evaluation Study
This randomized, phase 2, double-blinded, multicenter study is designed to assess the safety and immune response kinetics of CYFENDUS™ (henceforth AV7909) administered on 2 primary series vaccination schedules followed by 6- and…
- Trial name
- ABESt (NCT05997264)
- Testing
- AV7909 Full Dose (0.5 mL), AV7909 Half Dose (0.25 mL)
- Where
- 7 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
Heart Defects, Congenital
Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
The staged surgical pathway to treat children with single ventricle heart defects culminates with the Fontan operation. In this procedure, systemic venous return is rerouted directly to the pulmonary arteries, which serves to…
- Trial name
- NCT00543309
- Testing
- nesiritide, milrinone
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- John M Costello
Normal Physiological Response to Sweet Drinks
Brain and Glycemic Responses to Sweet Soft Drinks
The goal of this observational study is to determine changes in brain activity and blood sugar in response to the ingestion of flavored waters sweetened with either the nutritive sugar sucrose or different low-caloric sweeteners…
- Trial name
- SWEETBRAIN (NCT05575687)
- Testing
- Water (reference), Sucrose, Sucralose
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Vital Pulp Therapy
Bioactive Materials in Vital Pulp Therapy of Permanent Teeth
This randomized clinical study aimed to evaluate and compare the clinical, radiographic, and postoperative pain outcomes of direct pulp capping performed using two calcium silicate-based materials: ProRoot MTA and Biofactor MTA…
- Trial name
- NCT07562555
- Testing
- Direct pulp capping with ProRoot MTA, Direct pulp capping with BIOfactor MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ege University
Arrhythmias, Cardiac, Heart Block
Holter Versus Zio Patch Electrocardiographic Monitoring in Children
This prospective study aims to compare the diagnostic yield, or ability to detect an arrhythmia, of the traditional Holter monitor versus the novel Zio patch monitor in pediatric patients referred for ambulatory…
- Trial name
- NCT03309956
- Testing
- Holter Monitor, Zio Patch
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Columbia University
Unsedated Colonoscopy, Water Exchange Colonoscopy
Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy
This is a study to compare two different, but normally, used methods of colonoscopy in patients undergoing colonoscopy without sedation.
- Conditions
- Unsedated Colonoscopy, Water Exchange Colonoscopy, Cap, Colonoscopy Pain
- Trial name
- NCT03160859
- Testing
- Control, Study method
- Where
- 3 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Quality of Life
Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer
This study is examine the effect of the addition of naturopathic on immunologic and/or inflammatory parameters and/or quality of life in women receiving neoadjuvant chemotherapy for breast cancer.
- Trial name
- NCT02486796
- Testing
- Reishi mushroom extract, Coenzyme Q10, Melatonin
- Volunteers
- 5 people
- Sponsor
- Midwestern Regional Medical Center
Healthy
The Impact of a Regular Borjomi® Consumption on an Anaerobic Performance
The effects of 2 weeks 1000 ml daily mineral water Borjomy® consumption of anaerobic performance and acid-base balance in comparison with purified electrolite smart-water and still drinking water.
- Trial name
- NCT05494827
- Testing
- Regular consumption of natural mineral water Borjomi® with high bicarbonate content, Regular consumption of processed drinking water Smart Spring®, Regular consumption of still drinking water
- Where
- Russia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Zaynudin Zaynudinov, MD, PhD
Bowel Preparation Before Colonoscopy
Comparison of Electrolyte Beverages and Water as Solvents for Bowel Preparation
Using Electrolyte Beverages as replacement for water to dissolve PEG(2L plan) in bowel preparation process. The aim of this study is to test whether Electrolyte Beverages as solvents can improve the cleanness of bowel preparation…
- Trial name
- EBSBP-01 (NCT06675227)
- Testing
- electrolyte beverages
- Where
- China
- Volunteers
- 2,766 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Neuroblastoma Recurrent
Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma
Children, adolescents and young adults with high risk relapsed or treatment refractory neuroblastoma (rNB) represent a group of patients with dismal prognosis for whom a recommended standard salvage therapy is currently not…
- Trial name
- RIST-rNB-2011 (NCT01467986)
- Testing
- Dasatinib, Rapamycin, Irinotecan
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Regensburg
Pain Alleviation, Birth
The Effect of Sacral Massage and Sterile Water Injection During Childbirth on Pain Level and Birth Satisfaction
Childbirth is a physiological, psychological, and social process. Ineffective management of lower back pain during labor reduces oxygen supply to the fetus, increasing hypoxia, distress, perinatal morbidity, and mortality rates.
- Trial name
- Satisfaction (NCT07702773)
- Testing
- Sterile Water Injection, sacral press
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Staphylococcal Skin Infections, Abscesses
Staphylococcus Aureus Decolonization Study
The purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather…
- Conditions
- Staphylococcal Skin Infections, Abscesses, Furunculosis, Staphylococcus Aureus
- Trial name
- SuDS (NCT00731783)
- Testing
- 2% Mupirocin Ointment, 4% Chlorhexidine liquid soap, Hygiene protocol
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Washington University School of Medicine
Acute Myeloid Leukemia, Complex Karyotype
The Use of Decitabine as Induction Therapy for Acute Myeloid Leukemia With Complex and/or Monosomal Karyotype
Acute myeloid leukemia (AML) is a heterogeneous group of diseases with distinct clinicopathologic features sharing in common an abnormal increase in myeloblasts in blood and bone marrow (BM).
- Trial name
- NCT03080766
- Testing
- Decitabine
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
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