Clinical trials: Water
End-stage Renal Disease (ESRD), Hemodialysis
Oral L-carnitine and Inflammatory and Nutritional Biomarkers in Maintenance Hemodialysis
The goal of this clinical trial is to evaluate whether oral L-carnitine supplementation helps reduce inflammation and improve nutritional status in patients with end-stage kidney disease who are undergoing long-term hemodialysis.
- Trial name
- NCT07249229
- Testing
- L-carnitine 1000 Mg
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Darya Chamani
Cancer
Effect of Dance-based Multimodal Exercise for Managing CIPN in Cancer Patients
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant and distressing symptom experienced by cancer patients with different cancer types.
- Trial name
- NCT07632482
- Testing
- dance-based multimodal exercise, Exercise education
- Volunteers
- 76 people
- Sponsor
- Chinese University of Hong Kong
Capsule Endoscopy
Small Bowel Cleansing for Capsule Endoscopy in Pediatric Patients
The primary aim of this prospective, randomized and controlled study was to evaluate the effect of five bowel preparation regimens on small-bowel cleansing in a pediatric population.
- Trial name
- PREP-CE (NCT01783782)
- Testing
- DIET, polyethylene glycol 4000 solution with simethicon, simethicon
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Policlinico Umberto I
Osteoarthritis, Knee
Reaching Exercise Goals: Comparison of Exercise Means in Patients With Knee Osteoarthritis
The primary objective is to evaluate water based treadmill exercise, land based treadmill exercise, and upright cycling in meeting American College of Sports Medicine exercise goals for moderate exercise.
- Trial name
- NCT01359124
- Testing
- Exercise Cycle, Land-based Treadmill, Water-based Treadmill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
Optimal Gastrointestinal Absorption of Omega-3
A Study to Determine Optimal Absorption of Single Dose Omega-3
This is a randomised three-way cross over study comparing the optimal absorption of a single dose of fish oil using 3 different forms to one another on increasing blood concentrations of fatty acids in 24 healthy adult…
- Trial name
- NCT05491759
- Testing
- Product 1 - AquaCelle Fish Oil Triglyceride, Product 2 - AquaCelle Fish Oil Ethyl Ester, Product 3 - Standard Fish Oil Triglyceride
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
MDMA Discontinuation Syndrome
Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.
The purpose of this study is to measure the effects of MDMA on sleep, mood, thinking, and how your body retains water. The researchers are interested in the effects that occur a few hours after taking MDMA as well as effects…
- Trial name
- 2C (NCT01053403)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Healthy Individuals, Bioequivalence Study
Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistani Subjects
Single oral dose, of test and reference Tablet will be administered to healthy volunteers, after at least 10 hours fast together with 240 mL of ambient temperature water at their scheduled dosing time-points.
- Trial name
- BE (NCT04873570)
- Testing
- Moxifloxacin 400mg
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Purpose: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT03065673
- Testing
- Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Mantle Cell Lymphoma
Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma
This study is designed to evaluate the efficacy and safety of acalabrutinib plus bendamustine and rituximab followed by acalabrutinib plus cytarabine and rituximab in subjects with treatment naïve mantle cell lymphoma (MCL), as a…
- Trial name
- NCT03623373
- Testing
- Bendamustine, Rituximab, Acalabrutinib
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Colon Cleansing in Preparation for Colonoscopy
A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing
To demonstrate non inferiority of a) "FE 999169 Split Dosing Schedule" (one dose on the day before and the second dose on the day of colonoscopy) and b) "FE 999169 Day Before Dosing Schedule" (two doses on the day before…
- Trial name
- NCT02215954
- Testing
- FE 999169, Niflec
- Where
- 4 sites in Japan
- Volunteers
- 637 people
- Sponsor
- Ferring Pharmaceuticals
Breastmilk, Oral Care
Oral Care With Breast Milk in Preterm Newborns Fed by Tube
It was conducted to evaluate Oral Care with Breast Milk in Preterm Newborns Fed by Tube
- Trial name
- NCT06129266
- Testing
- oral care with breastmilk
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Advanced Tumours
Study of LM-061 in Subjects in Advanced Tumors
This is a phase I, open-label, dose escalation study to evaluate the safety, tolerability, PK, and preliminary efficacy of LM-061 in subjects with advanced tumors.
- Trial name
- NCT04737122
- Testing
- LM-061, Toripalimab
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- LaNova Medicines Limited
Aortic Surgery, Extracorporeal Circulation
Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC)
Antibiotic prophylaxis is essential for all types of cardiac surgery under Extracorporeal Circulation (ECC), in order to reduce the incidence of surgical site infection (SSI).
- Trial name
- CLINDAPASS (NCT07267013)
- Testing
- Clindamycin
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Nantes University Hospital
Pneumonia, Mechanical Ventilation Complication
Oral Care of Intubated Intensive Care Patient
The aim of the research was to examine the effect of oral care bundle application on oral health, salivary pH (power of hydrogen), dry mouth and ventilator associated pneumonia in intubated patients compared to standard oral care.
- Conditions
- Pneumonia, Mechanical Ventilation Complication, Salivation, Dry Mouth
- Trial name
- NCT06258603
- Testing
- oral care bundle, clinical oral care
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Human Nutrition
Effect of Intake of Hydrolyzed Krill Protein Isolate on Plasma Amino Acid Profile
Purpose: To examine the absorption of three different protein sources: hydrolyzed krill protein isolate, whey protein isolate, and soy protein isolate.
- Trial name
- KRILL (NCT04864769)
- Testing
- Krill protein hydrolysate, Soy protein isolate, Whey protein isolate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Diarrhea
Study to Compare the Pharmacokinetics Profiles of Four Racecadotril Products
This study is designed to compare the pharmacokinetics of four products used for treatment of acute diarrhea.
- Trial name
- NCT01476683
- Testing
- Racecadotril
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Gastrointestinal Dysfunction
Gastric Emptying Validation Pilot Study (MRI Val)
The primary aim of this study is to assess (in healthy volunteers) the rate at which a glucose drink leaves the stomach by sequential magnetic resonance imaging (MRI) of the stomach contents using a 0.5 tesla upright MRI scanner…
- Trial name
- MRIVal (NCT05765123)
- Testing
- Oral glucose tolerance test
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Head and Neck Cancer, Mucositis
Magic Mouthwash Plus Sucralfate Versus Benzydamine Hydrochloride for the Treatment of Radiation-induced Mucositis
Radiation treatment is very effective for treating cancers of the head and neck, however, during the course of treatment, it is common for patients to experience soreness of their mouth and throat due to the radiation.
- Trial name
- NCT00814359
- Testing
- Combination of Magic Mouthwash Plus Sucralfate, 0.15% Benzydamine HCl
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Juravinski Cancer Centre Foundation
Healthy
Investigate Absorption, Metabolism, Excretion, and Mass Balance of Pacritinib
This study is an open-label, absorption, metabolism, excretion, and mass balance study of 400 mg [14C]pacritinib (containing 100 μCi radioactivity) administered orally as a single dose to 6 healthy male subjects following at…
- Trial name
- NCT02803762
- Testing
- Pacritinib
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- CTI BioPharma
Molar Incisor Hypomineralization
Three Approaches of Resin Infiltration for MIH Incisor Opacities
Molar incisor hypomineralization (MIH) is a condition which involves enamel hypomineralization of one to four first permanent molars with or without permanent incisors.
- Trial name
- NCT07715370
- Testing
- Resin infiltration, microabrasion, Etch-bleach
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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