Clinical trials: Water, completed
Influenza
Assessment of CR8020, a Monoclonal Antibody Against Influenza A Viruses
The purpose of this study is to assess in healthy subjects the safety, tolerability, pharmacokinetics and immunogenicity of single escalating doses of CR8020, a monoclonal antibody against influenza A viruses.
- Trial name
- NCT01756950
- Testing
- 2 mg/kg CR8020, 5 mg/kg CR8020, 15 mg/kg CR8020
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Opioid-Related Disorders, Substance-Related Disorders
Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000250
- Testing
- 0% N2O, 40% N2O
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Molar Incisor Hypomineralization
Evaluation of the Effectiveness of Various Desensitizing Treatment Protocols
The objective of this research was to evaluate the clinical success of desensitization treatments using four different materials in the first permanent molars (FPMs) affected by MIH.
- Trial name
- NCT07085689
- Testing
- Sodium Fluoride Varnish (5%), Silver diamine fluoride- potassium iodide, Aqueous Silver Fluoride
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hacettepe University
Coffee
Acute Effects of Instant Coffee in Capsule vs Beverage Form on Plasma Metabolites
This study is designed to evaluate the acute effect of consuming a cup of instant coffee on circulating metabolites and to evaluate whether ingestion of instant coffee in the form of a capsule has a similar effect on circulating…
- Trial name
- NCT07051291
- Testing
- Instant Coffee Capsule, Instant Coffee Beverage
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
This single center study will investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving DH compared with a standard fluoride dentifrice after short term use.
- Trial name
- NCT02924350
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United Kingdom
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postoperative Pulmonary Complications, Respiratory Insufficiency
The PROtective Ventilation Using Open Lung Approach Or Not Trial
Postoperative Pulmonary Complications (PPC) are very common. It severely affects postoperative recovery, particularly in the abdominal surgery.
- Trial name
- PROVOLON (NCT03160144)
- Testing
- open lung approach
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Primary Dysmenorrhea
Effect of a Magnesium Sulfate Footbath on Primary Dysmenorrhea Pain
Primary dysmenorrhea is a common condition characterized by painful menstruation. This three-arm randomized controlled trial evaluated the effect of a warm-water footbath containing magnesium sulfate on primary dysmenorrhea pain.
- Trial name
- NCT07726264
- Testing
- Magnesium Sulfate Warm-Water Footbath, Warm-Water Footbath
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kocaeli University
Gastrointestinal Symptoms
Effect of Physical Form of Apples on Gastrointestinal Function and Satiety: a MRI Study
Different physical form of apples had a significant effect on satiety and blood sugar levels which was shown in a 1977 study by Haber and his team (Haber et al.1977).It was suggested that , this effect was due to processing of…
- Trial name
- NCT03714464
- Testing
- Whole apples, Apple puree, Apple Juice
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
Advanced Solid Tumors, Metastatic Breast Cancer
Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Study has two parts: 1. Dose-finding: to determine the maximum tolerated dose (MTD) and to evaluate the safety and tolerability of RAD001 (everolimus , Afinitor®) in combination with BEZ235 in patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumors, Metastatic Breast Cancer, Metastatic Renal Cell Carcinoma
- Trial name
- NCT01482156
- Testing
- RAD001 + BEZ235
- Where
- 10 sites in United States, Belgium and 5 more
- Volunteers
- 46 people
- Sponsor
- Novartis Pharmaceuticals
Overweight and Obesity, PreDiabetes
Effect of Time-restricted Eating on Behaviour and Metabolism in Overweight Individuals at High Risk of Type 2 Diabetes
The aim of the present study is to investigate effects of 12 weeks time-restricted eating on behaviour and metabolism in individuals with overweight or obesity at high risk of type 2 diabetes.
- Trial name
- RESET (NCT03854656)
- Testing
- Time-restricted eating
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kristine Færch
Metabolic Syndrome, Insulin Resistance
Continuous Tart Cherry Juice Supplementation With Metabolic Syndrome Participants
The present study examined the effect of Montmorency tart cherry juice on functional and blood-based cardio-metabolic markers in humans with Metabolic Syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Hypertension
- Trial name
- NCT03619941
- Testing
- Montmorency Tart Cherry Juice
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Hertfordshire
Glycemic Index
Safety and Efficacy of a Single Dose of a Polyphenol-enriched Brown Seaweed Powder in Human
The primary endpoint of this trial will be to evaluate the safety of a single administration in human of a dose of 500 mg of a polyphenol-rich algal powder when taken 30 minutes before a test meal.
- Trial name
- ICAST (NCT00936754)
- Testing
- Brown seaweed powder
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- innoVactiv Inc.
Chagas Disease, Chagas Cardiomyopathy
Physical Exercise Program in Chronic Chagas Heart Disease
The aim of this investigation is to evaluate the impact of exercise in a cardiac rehabilitation program on functional capacity, clinical markers, quality of life and biomarkers in patients with chronic chagasic cardiomyopathy.
- Trial name
- PEACH (NCT02517632)
- Testing
- Exercise, nutritional and pharmaceutical counceling, Nutritional and pharmaceutical counceling
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Acute Mountain Sickness (AMS)
Safety and Efficacy of T89 in Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)
Acute mountain sickness (AMS) is one of three syndromes of altitude illness. It is very common when people venture over 2500 meters altitude.
- Trial name
- NCT03552263
- Testing
- T89 capsule
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tasly Pharmaceuticals, Inc.
Avian Influenza
H7N9 Mix and Match With MF59 in Healthy Elderly Persons
This is a Phase II randomized, partially-blinded, controlled trial in 360 (up to 600) males and females, 65 years of age and older, who are in good health and meet all eligibility criteria.
- Trial name
- NCT02213354
- Testing
- MF59, Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
- Where
- 10 sites in United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Thyroid Goiter, Hypothyroidism
Energy Metabolism in Thyroidectomized Patients
The purpose of this research study is to measure the changes in energy metabolism (how the body burns energy), cardiovascular function (heart function), and lipid metabolism (cholesterol break down and building) before and after…
- Conditions
- Thyroid Goiter, Hypothyroidism, Thyroid Cancer
- Trial name
- NCT04782856
- Testing
- Levothyroxine, Liothyronine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Alzheimer's Disease, Brain Neoplasm
PET Scan of Brain Metabolism in Relation to Age and Disease
The main source of energy for the brain comes from a combination of oxygen and glucose (sugar). For brain cells to function normally they must receive a constant supply of these nutrients.
- Conditions
- Alzheimer's Disease, Brain Neoplasm, Niemann Pick Disease
- Trial name
- NCT00001972
- Testing
- 15 O Water
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Colon, Irritable
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
The challenge is to understand how fibre interacts with whole-gut function to alter colonic fermentation of fermentable oligo-di- and mono-saccharides and polyhydric alcohols (FODMAPs).
- Trial name
- RUFUS (NCT06291272)
- Testing
- Psyllium, Methylcellulose, Inulin
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Lower Urinary Tract Symptoms
The Efficacy of Nano-water in Combination With Tamsulosin- Dutasteride for Lower Urinary Tract Symptoms
The goal of this clinical trial is to learn if nano-water combined with tamsulosin and dutasteride can relieve the symptoms of lower urinary tract symptoms in adults with benign prostatic hyperplasia .
- Trial name
- NCT06677177
- Testing
- Nano-water, Tamsulosin Dutasteride, Regular water, tamsulosin, Dutasteride
- Where
- Iraq
- Volunteers
- 210 people
- Sponsor
- ALI KAMAL M. SAMI
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