Clinical trials: Water
Head and Neck Cancers, Oral Mucositis
Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis
This study was conducted to compare the effectiveness of thyme honey, saline and sodium bicarbonate solution in the management of oral mucositis in patients with head and neck cancer receiving radiotherapy.
- Trial name
- NCT05648682
- Testing
- Salin, Sodium bicarbonate, Thyme honey
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Major Depressive Disorder
Bear Bile Pill as add-on the Treatment of MDD
This is a single-center, double blind, randomized, placebo-controlled, parallel group study of bear bile pill, as add-on therapy in MDD patients conducted in Shang Hai Mental Health Center.
- Trial name
- NCT04509882
- Testing
- bear bile pill
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Postoperative Ileus
Study to Evaluate the Safety of Post-Operative TZP-101 (IV Ulimorelin) After Partial Bowel Resection
A study to evaluate the safety of TZP-101 in comparison with placebo when administered post-operatively in patients who have undergone partial bowel resection.
- Trial name
- NCT01710982
- Testing
- TZP-101
- Volunteers
- 27 people
- Sponsor
- Norgine
Skin Sensitivity, Trans-epidermal Water Loss
Two Supplemented Against Skin Reactivity
In recent decades, the incidence of subjects presenting reactive skin has considerably increased in industrialized countries. Probiotics are live microorganisms which, when ingested in sufficient amounts, have beneficial effects…
- Conditions
- Skin Sensitivity, Trans-epidermal Water Loss, Clinical Score, Assessment of Skin Moisturization Factors
- Trial name
- NCT01368224
- Testing
- Lactobacillus paracasei NCC 2461 and Bifidobacterium longum NCC3001
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Childhood Obesity
Improving Cardiometabolic Health of Youth on Antipsychotic Medication
Pediatric antipsychotic treatment is associated with significant obesity-related side effects, including weight gain, increased blood sugar, abnormal cholesterol, and risk of new onset diabetes.
- Trial name
- NCT02877823
- Testing
- Treatment, Control
- Volunteers
- 302 people
- Sponsor
- University of Maryland, Baltimore
Heart Failure
An Automated Continual Water Removal System in Patients With Advanced Diuretic Resistant Heart Failure
This study will assess the functionality and tolerability of an automated continual water removal system in up to 8 patients with HF and diuretic resistance.
- Trial name
- ACWR-HF (NCT05140759)
- Testing
- automated continual water removal system
- Where
- 3 sites in Georgia, Israel and 1 more
- Volunteers
- 3 people
- Sponsor
- Paragate Medical LTD
Feasibility
Feasibility and Acceptability Followed by Effectiveness of bCPAP for Treatment of Bangladeshi Children With Severe Pneumonia
Background: Feasibility and acceptability of bubble continuous positive airway pressure (CPAP) were not evaluated in childhood severe pneumonia in developing countries at a larger scale. Objective: 1.
- Trial name
- Child-bCPAP (NCT05239559)
- Testing
- Bubble CPAP oxygen delivery device
- Where
- 2 sites in Bangladesh
- Volunteers
- 20 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Non-Small Cell Lung Cancer With EGFR Mutation, Brain Metastases
Keynatinib in Treated Patients With NSCLC and Brain Metastases
The purpose of this study is to evaluate the safety and efficacy of Keynatinib capsules in patients with advanced non-small cell lung cancer (NSCLC) with brain metastasis or progression of brain metastasis after treatment with…
- Trial name
- NCT04824079
- Testing
- Keynatinib
- Where
- 5 sites in China
- Volunteers
- 16 people
- Sponsor
- Medolution Ltd.
Pancreatic Cancer
Imatinib Mesylate and Gemcitabine in Treating Patients With Locally Advanced, Metastatic, or Recurrent Pancreatic Cancer
RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells…
- Trial name
- NCT00281996
- Testing
- Gemcitabine, Imatinib mesylate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University
Labor Pain, Duration of Labor
Effect of Hot Pack on Labor Pain, Duration of Labor, and Satisfaction of Primigravidae Women in Saudi Arabia
The study aimed at determining the effect of hot pack on labor pain reduction and the duration of labor in comparison with routine care.
- Conditions
- Labor Pain, Duration of Labor, Satisfaction
- Trial name
- NCT04177888
- Testing
- Hot Pack
- Where
- Saudi Arabia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- King Saud University
Chronic Kidney Disease Stage 3 and 4
Safety and Efficacy of Paricalcitol Capsules in Decreasing Serum Parathyroid Hormone Levels in Children Aged 10-16 With Chronic Kidney Disease (CKD)
Part 1: To determine the safety, tolerability, and pharmacokinetics of a single dose of 3 μg paricalcitol capsules in children ages 10 to 16 years with moderate to severe chronic kidney disease (CKD Stages 3 and 4).
- Trial name
- NCT01020487
- Testing
- Paricalcitol
- Volunteers
- 47 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Asthma
Busonid® (Budesonide 200 mcg and 400 mcg) to Treat Asthma Not Controlled or Partially Controlled
National clinical trial, phase III, multicenter, single-arm, efficacy study, 80 participants of both sexes, aged equal or more than 12 and less than 65 years.
- Trial name
- Laennec (NCT02853578)
- Testing
- Busonid (budesonide 200mcg and 400mcg)
- Where
- 5 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Child Nutritional Status, Household Dietary Diversity
Impact Evaluation of the DFID Programme to Accelerate Improved Nutrition of the Extreme Poor in Bangladesh
This is a randomized study in three areas of Bangladesh (Chars region where CLP operates, Haor region where Shiree operates, and urban slums where UPPR operates).
- Conditions
- Child Nutritional Status, Household Dietary Diversity, Maternal Nutrition Knowledge and Practices
- Trial name
- NCT02597608
- Testing
- CLP: Livelihoods, CLP: Nutrition, Shiree: Livelihoods
- Where
- Bangladesh
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Atopic Dermatitis, Eczema
Evaluating Skin Barrier Dysfunction in Infants at High Risk of Atopy
It is hypothesized that food allergy is preceded by atopic dermatitis (AD), due to a disruption of skin barrier which can predispose one to food sensitization through the skin.
- Conditions
- Atopic Dermatitis, Eczema, Food Allergy
- Trial name
- NCT03089476
- Testing
- Evaluating atopy in infants, Evaluating TEWL and STS in adults
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Jewish Health
Carbohydrate, Caffeine
Carbohydrate Rinsing and Caffeine Gum on Performance of Romanian Deadlifts Performance
Two experiments were completed to investigate the effects of carbohydrate mouth rinsing and caffeine gum chewing on inertial resistance exercise performance.
- Trial name
- NCT05900349
- Testing
- Carbohydrate mouth rinsing, 200 mg caffeine gum
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Dehydration
Dehydration Among School Children- Mali
There is a large body of evidence from adult populations suggesting cognition in adults is affected by hydration status. The few studies conducted in the global North in populations of schoolchildren indicate that drinking water…
- Trial name
- NCT01768234
- Testing
- Supplemental water
- Where
- Mali
- Volunteers
- 120 people
- Sponsor
- Emory University
Gastrointestinal Disease, Flatulence
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption
The oligosaccharide content (raffinose, stachyose, and verbascose) in legumes would be responsible for gastrointestinal symptoms (bloating, pain, meteorism), associated with its consumption.
- Conditions
- Gastrointestinal Disease, Flatulence, Gastrointestinal Tolerance, Distension; Bowel
- Trial name
- NCT04243187
- Testing
- Chilean Native Beans
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Natalia Jara
Metabolic Disturbance
Smoothies and Blood Sugars
Glycaemic responses to fruit smoothies may depend on the food matrix (e.g., degree of processing and physical structure), ingestion rate, dose ingested and fibre content.
- Trial name
- NCT06333184
- Testing
- Food
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Bath
Severe Acute Malnutrition
Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
The primary outcome of the study is to identify gastrointestinal tolerance of under-five children with severe acute malnutrition to ready-to-drink high energy (1.5 kcal/ml) and standard energy (1 kcal/ml) oral nutrition…
- Trial name
- NCT04715204
- Testing
- High Energy Oral Nutrition Supplement, Standard Energy Oral Nutrition Supplement, Formula-75/Formula-100
- Where
- 2 sites in Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Dry Skin
A Capacitance and Transepidermal Water Loss Test to Determine the Ability of Sunscreen to Moisturize Skin
To evaluate the ability of 2 Helioblock SX Cream formulations to moisturize skin using capacitance and transepidermal water loss methodology
- Trial name
- NCT00368563
- Testing
- Helioblock SX
- Where
- United States
- Sponsor
- Loreal USA
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