Clinical trials: Water, completed
Dental Plaque
Supragingival Plaque Removal With and Without Dentifrice
Purpose: The aim of this study was to compare the efficacy of dental biofilm removal by brushing with and without conventional toothpaste.
- Trial name
- NCT01986972
- Testing
- Toothbrushing With Dentifrice, Toothbrushing Without Dentifrice
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Franciscan University Center
Effect of Glucagon-like Peptide 2 on Gallbladder Motility
Effect of Glucagon-like Peptide 2 on Gallbladder Motility After a Meal in Young, Healthy Male Subjects
The study will investigate the effect of the incretin hormone glucagon-like peptide 2 (GLP-2) on postprandial gallbladder motility in young, healthy, male subjects. The study is double-blinded, randomized and placebo controlled.
- Trial name
- NCT03682172
- Testing
- GLP-2 (1pmol/kg/min), GLP-2 (10pmol/kg/min)
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Necator Americanus Infection
Repeated Controlled Human Hookworm Infection
Twenty-four healthy hookworm-naive volunteers will be exposed to 50 L3 Necator americanus larvae for a maximum of three times.
- Trial name
- ReCHHI1 (NCT03257072)
- Testing
- 50 Necator americanus L3 larvae, 100 Necator americanus L3 larvae, 150 Necator americanus L3 larvae
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Meta Roestenberg
Healthy Subjects
Bioequivalence Study of Ribavirin in Healthy Adult Subjects Under Fed Condition
To evaluate and compare the relative plasma bioavailability and therefore the bioequivalence of two different immediate release products each containing Ribavirin 400 mg, after administering a single oral dose, to healthy adult…
- Trial name
- NCT05532306
- Testing
- Ribavirin 400 mg film coated tablet (1*400mg), Copegus® 200 mg film coated tablet (2*200mg)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Parkinson Disease
Aquatic Therapy Versus Land-Based Therapy for the Treatment of Balance Dysfunction in Parkinson's Disease
The aim of this study is to compare the effectiveness of a specific aquatic therapy program on balance with a land-based physical-treatment in patients with Parkinson's disease and to evaluate the long-term effects in a 6-month…
- Trial name
- NCT02701621
- Testing
- MIRT-AT, MIRT
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Healthy
A Single and Multiple Dose Study to Assess How the Drug Enters, Moves Through and Exits the Body, Safety and Tolerability of Safinamide in Healthy Adult Chinese Volunteers
This is a Phase I, single center, single and multiple-dose, open-label, randomised, parallel-group, pharmacokinetics, safety and tolerability study.
- Trial name
- NCT03887221
- Testing
- Safinamide 50 mg, Safinamide 100mg
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zambon SpA
Dental Plaque, Orthodontic Patients
Comparison of the Effectiveness of Miswak and Manual Toothbrush in Removing Dental Plaque in Fixed Orthodontic Patients
This study compares the immediate plaque removal efficacy of the natural Miswak versus a traditional manual toothbrush using the Modified Bass technique among orthodontic patients.
- Trial name
- NCT07619014
- Testing
- Natural Miswak (Al-Kureysh, Pakistan), Manual Toothbrush (Colgate Zig Zag, China)
- Where
- Syria
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Hawash Private University
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Multicenter Evaluation of Right Colon Polyp Miss Rates Using Water Exchange Versus CO2 Insufflation
A prospective multicenter randomized controlled trial (RCT) comparing water exchange (WE) colonoscopy and carbon dioxide (CO2) insufflation in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate…
- Trial name
- NCT04124393
- Testing
- Colon Polypectomy
- Where
- Taiwan
- Volunteers
- 386 people
- Sponsor
- Evergreen General Hospital, Taiwan
Metabolic Disease
Screening of Phytochemical Rich Ingredients as 'Functional Foods' to Improve Cardiometabolic Health
To find out whether consumption of different kinds of plant based functional food ingredients, traditionally used in Asia, can improve post-meal response of indicators of heart and metabolic (cardiometabolic) function.
- Trial name
- PRIFF (NCT03685916)
- Testing
- Control, Cumin Rice, Cumin Drink
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Chronic Fatigue Syndrome
SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE)
The investigators wish to investigate whether enhancement of SWS, which is seen after a drug called sodium oxybate, reduces the impact of sleep disruption in CFS on daytime function, specifically sleepiness and mental…
- Trial name
- SAFFE (NCT02055898)
- Testing
- Sodium Oxybate
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Imperial College London
Diabetes Mellitus, Type 2
To Bathe or Not to Bathe
Type 2 diabetes mellitus (T2DM) is characterised by chronic high blood sugar concentration (hyperglycaemia) and insulin resistance leading to a reduction in insulin sensitivity.
- Trial name
- NCT03798717
- Testing
- Heating
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Diet Habit
Evaluating a Healthy Restaurant Kids Meals Policy
More than a dozen municipalities have passed healthy default kids' beverage policies. These policies seek to reduce child consumption of sugar-sweetened beverages (SSBs) by requiring that restaurants serve only healthy beverages…
- Trial name
- NCT04330235
- Testing
- Healthy Default Kids' Beverage Policy
- Where
- 3 sites in United States
- Volunteers
- 3,480 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type 2 Diabetes Mellitus
GLP-1-mediated Gluco-metabolic Effects of Bile Acid Sequestration
The objective of this study is to investigate the potential GLP-1-mediated contribution to the well-established glucose-lowering effect of sevelamer-induced bile acid sequestration .
- Trial name
- SeveX (NCT03739268)
- Testing
- Sevelamer
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Steno Diabetes Center Copenhagen
Healthy Volunteers Pharmacokinetic Study
Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK
The purpose of the study is to assess the safety, tolerability and PK of selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in healthy male Japanese and non-Japanese Asian volunteers following administration of a single dose.
- Trial name
- NCT01960374
- Testing
- Selumetinib
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gastroenteritis Acute, Vomiting
Sucrose at Triage for Acute Gastroenteritis Episode in Children
Background: Acute viral gastroenteritis is a very common pediatric medical condition that results in a large number of emergency department (ED) visits.
- Trial name
- STAGE (NCT05378776)
- Testing
- sucrose, Standard rehydration solution
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Jocelyn Gravel
Cardiac Surgery
Comparison of the Administration of Levosimendan and Placebo in the Preparation of Critical Patients for Heart Surgery
This study aims to examine the efficacy of levosimendan in terms of reducing postoperative mortality and severe morbidity in patients undergoing non-emergent surgery for coronary revascularisation with or without ischaemic mitral…
- Trial name
- NCT01595737
- Testing
- Levosimendan
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Covid19
Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients
Randomized, double-blind, placebo-controlled pilot study to evalaute viral load in saliva of COVID19+ patients using quantitative PCR, before and after use of active or placebo rinses
- Trial name
- NCT04563689
- Testing
- CHX0.12+CPC0.05 oral rinse (PerioAidActive Control)
- Where
- Colombia
- Volunteers
- 23 people
- Sponsor
- Dentaid SL
Xerostomia
A Clinical Study to Evaluate the Efficacy of Three Dry Mouth Relief Products Versus Water
This study assessed the efficacy of three dry mouth products (including an experimental Oralbalance gel, oral rinse, and moisturizing spray) to relieve the feeling of dry mouth compared to water, in dry mouth population over a…
- Trial name
- NCT03494985
- Testing
- Experimental Oralbalance Moisturizing Gel, Biotene Original Oral Rinse, Biotene Moisturizing Mouth Spray
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cerebrovascular Circulation, Affect
The Effect of Tea Breaks on Cerebrovascular Perfusion During Desk Work
Sedentary behaviour of healthy subjects may have a detrimental impact on cerebral blood flow as well as cognitive measures related to mood and alertness.
- Trial name
- NCT03953391
- Testing
- Tea, Water
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
SBO - Small Bowel Obstruction
A Multicenter Retrospective Review of Management Strategies in Small Bowel Obstruction
The objective of the study is to review performance of water soluble contrast study in patients admitted with Small Bowel Obstruction(SBO), will improve quality and safety, and decrease length of stay and morbidity.
- Trial name
- NCT06223620
- Testing
- review performance of water soluble contrast
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- Methodist Health System
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