Clinical trials: Water
Intrahepatic Cholangiocarcinoma
Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection
This study is a single-arm, open-label, exploratory clinical trial, with the primary objective to evaluate the efficacy and safety of the Neoantigen Vaccine plus capecitabine for the treatment of high-intermediate risk recurrent…
- Trial name
- NCT06406816
- Testing
- Neoantigen Vaccine plus Capecitabine
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Yongyi Zeng
Restless Legs Syndrome, Pregnant
The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome
This study was planned as a randomized controlled study to determine the effect of hot and cold water application on complaints and sleep quality in pregnant women with restless legs syndrome (RLS).
- Conditions
- Restless Legs Syndrome, Pregnant, Sleep Disorder
- Trial name
- RLS (NCT04786314)
- Testing
- Hot Water Application, Cold Water Application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
HIV I Infection
Safety and Efficacy of Romidepsin and the Therapeutic Vaccine Vacc-4x for Reduction of the Latent HIV-1 Reservoir
The REDUC trial's objective is to address one of the core issues with the treatment of HIV, which is that some HIV infected cells hide in so-called latent reservoirs.
- Trial name
- REDUC (NCT02092116)
- Testing
- Romidepsin, Vacc-4x, rhuGM-CSF
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Bionor Immuno AS
Colon Polyp
Water-only Versus Water-CO2 (Hybrid) Colonoscopy Insertion Technique
The colonoscopy procedure involves insertion of a thin, flexible tube with a tiny camera inside (colonoscope) passed inside the bowel.
- Trial name
- WAVE (NCT04710706)
- Testing
- Colonoscopy insertion technique used during procedure
- Where
- United Kingdom
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Healthy
To Determine the Effect of Phaseolean on Glycemic Response to Carbohydrate Rich Meal in Healthy Adult Human Participants
This is an Open-Label, Randomized, Three-Way, Three-Arm, Crossover, Balance Study to Evaluate the Effect of Phaseolean on Glycemic response to carbohydrate rich meals in Healthy Adult Participants Using an In Vivo Method.
- Trial name
- PHEGI (NCT07466667)
- Testing
- Phaseolean (White Kidney Bean Extract) 1000 milligrams, Phaseolean (White Kidney Bean Extract) 2000 milligrams, Anhydrous Glucose Powder
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Breast Cancer
Single-arm, Multi-center Clinical Study of Pyrotinib Maleate Tablets Combined With Albumin-bound Paclitaxel and Trastuzumab in Neoadjuvant Treatment of Her2-positive Early or Locally Advanced Breast Cancer
This study aimed to evaluate the Pyrotinib in combination with albumin-bound paclitaxel and trastuzumab to neoadjuvant therapy efficacy and safety of Her2-positive early or locally advanced breast cancer
- Trial name
- NCT04917900
- Testing
- Pyrotinib combined with albumin-bound paclitaxel and trastuzumab
- Where
- China
- Volunteers
- 216 people
- Sponsor
- West China Hospital
Abdominal Obesity
Effects of Chicken Protein Hydrolysate (CPH) Supplementation in People With High Waist Circumference
In this randomized, placebo controlled, double blind trial, effects of relatively high doses of chicken protein hydrolysate (CPH) or casein hydrolysate (placebo) supplementation will be investigate in healthy persons with…
- Trial name
- CHICKPEP (NCT05149092)
- Testing
- Chicken protein hydrolysate supplement
- Where
- Norway
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Obesity
The Obese Taste Bud Study
The sense of taste is essential for priming food preferences and is therefore important for caloric uptake and body weight regulation.
- Trial name
- OTB (NCT04633109)
- Testing
- taste bud biopsy, oral glucose tolerance test, Taste sensitivity
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Hydrotherapy
The Effect of Therapeutic Play on Pain, Fear and Emotional Indicator
This study was planned to determine the effect of therapeutic play and preparation for hydrotherapy treatment on pain, fear and emotional indicator levels in children with burn injuries.
- Trial name
- NCT05808738
- Testing
- therapeutic play
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Bowel Preparation
Aquanet Bowel Cleansing Device Versus Oral Sodium Picosulfate for Pre-endoscopy Bowel Preparation
Poor or inadequate bowel preparation is one of the most common reasons for a repeated or failed colonoscopy. Preparation methods shown to be effective include the use of either bowel-cleansing devices or oral laxatives.
- Trial name
- NCT03074448
- Testing
- Aquanet, Sodium Picosulfate
- Where
- Brazil
- Volunteers
- 314 people
- Sponsor
- Kaiser Clinic and Hospital
Venous Leg Ulcer (VLU)
An Open Label, Single Treatment, Single Arm, Multiple Dose Phase-2 Study to Evaluate the Pharmacokinetics, Safety, and Clinical Performance of EscharEx (EX-03) in Participants With Venous Leg Ulcers
This is a pharmacokinetics (PK) study - the main objective of this study is to assess the PK, safety and clinical performance of 5% EscharEx (EX-03 formulation) in debridement of Venous Leg Ulcers
- Trial name
- NCT07692178
- Testing
- EX-03
- Volunteers
- 20 people
- Sponsor
- MediWound Ltd
Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure.
Disgust and Shame Based Safe Water and Handwashing Promotion
An estimated 2.2 million children under the age of 5 years die from diarrheal disease each year. Most of the burden of diarrheal disease is thought to be preventable with improvements in sanitation, water quality, and hygiene.
- Conditions
- Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure., Identify New Methods for Measuring Hand Washing and Water Treatment Behaviour., Compare the Effectiveness of the Disgust and Shame Based Interventions With Standard Public Health Interventions.
- Trial name
- NCT02037243
- Testing
- Standard Public Health Intervention with Water Treatment, Standard Public Health Intervention with Water Treatment & Hand Washing
- Where
- Bangladesh
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Ozone, Third Molar
Effects of Ozonated Water on Pain, Swelling, Trismus and Quality of Life in Third Molar Surgery
The aim of this study was to evaluate the effect of ozonated water on pain, edema and trismus after third molar removal. Patients were submitted to extraction of lower third molar under irrigation with ozonated water or doubly…
- Conditions
- Ozone, Third Molar, Clinical Trial
- Trial name
- NCT03501225
- Testing
- ozone, water
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Long COVID, Long Coronavirus Disease 2019 (Covid19)
RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG)
This study is a platform protocol designed to be flexible so that it is suitable for a wide range of settings within health care systems and in community settings where it can be integrated into COVID-19 programs and subsequent…
- Conditions
- Long COVID, Long Coronavirus Disease 2019 (Covid19), Long Covid-19
- Trial name
- NCT06305793
- Testing
- IVIG (intravenous immunoglobulin), Coordinated Care, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Kanecia Obie Zimmerman
Sleep Restriction
Nutrition Intervention to Promote Immune Recovery From Sleep Restriction
Physical and psychological stress on Warfighters during training and operational missions can suppress immune responsiveness. Skin wound models can be used to detect changes in immune function.
- Trial name
- NCT03525184
- Testing
- Additional protein and multi-nutrient beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Epiphora Due to Insufficient Drainage
OCT Guided Punctal Stenosis Management
This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.
- Trial name
- NCT04318652
- Testing
- Methylprednisolone eyedrops
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Halitosis
Laser Tongue Debridement for Oral Malodor
Malodor is a multifactorial condition with oral pathology representing the main culprit and the tongue being the first to second contributor to the malodor.
- Trial name
- NCT04120948
- Testing
- Waterlase Express Laser System, Tongue scraper
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Bloating, Gastrointestinal Symptoms
A Clinical Trial to Investigate the Safety and Efficacy of Bloat on Postprandial Bloating and Its Effects Over Time in Healthy Women
The goal of this clinical trial is to investigate the safety and efficacy of Bloat on postprandial bloating in healthy women. The main question it aims to answer is what is the difference in change in bloating from pre-dose…
- Conditions
- Bloating, Gastrointestinal Symptoms, Intestinal Gas
- Trial name
- NCT07370740
- Testing
- Bloat
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Arrae
Sudden Deafness, Sensorineural Hearing Loss
Autologous Blood Monocyte Vesicles for the Treatment of Sudden Deafness
Sudden deafness is a common emergency in otorhinolaryngology. As the etiology and mechanism of sudden deafness remains unknown, there is no specific treatment.
- Trial name
- NCT06707389
- Testing
- autologous blood monocyte vesicles (lower dose), Methylprednisolone, autologous blood monocyte vesicles (higher dose)
- Volunteers
- 30 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Healthy
A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy People
This is a phase 1 trial to evaluate the safety, tolerability, and pharmacokinetics of 4 different oral formulations of LEO 32731 in healthy subjects. The trial will be conducted in 3 parts at a single site.
- Trial name
- NCT03812198
- Testing
- LEO 32731 modified release tablet, LEO 32731 blend, hard capsule, LEO 32731 API, hard capsule
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
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