Clinical trials: Water
Anastomosis
Mechanical Bowel Preparation for Elective Colorectal Anastomosis
Colorectal surgery is highly associated with septic complications, therefore, multiple approaches have been used to reduce this complications, one of the most used is mechanical bowel preparation.
- Trial name
- NCT02731963
- Testing
- Polyethylene glycol
- Where
- Mexico
- Volunteers
- 81 people
- Sponsor
- Instituto Mexicano del Seguro Social
Castrate-resistant Prostate Cancer
A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer
There will be two parts to this clinical research study. The purpose of each part is: Phase 1: This part of the study will determine what dose of BEZ235 is safe to give with a standard dose of abiraterone acetate and prednisone…
- Trial name
- NCT01717898
- Testing
- BEZ235, Prednisone, Abiraterone acetate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Charles Ryan
Athletes, Respiratory Infection
Vitamin D Level Among Athletes in Uzbekistan
The purpose of the study is to determine vitamin D (VD) levels and upper respiratory tract infections (URTI) morbidity among elite athletes engaged in water sports in Uzbekistan.
- Conditions
- Athletes, Respiratory Infection, Cytokines, Vitamin D
- Trial name
- NCT03623763
- Testing
- Serologic tests of blood samples
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain
Effects of Food Form and Fitness on Appetite and Digestion.
Energy-yielding fluids induce weaker appetitive and compensatory dietary responses than energy-matched semi-solids or solids. This is problematic because the high and increasing contribution of energy from beverages in the diet…
- Trial name
- NCT01070199
- Testing
- liquid to liquid, liquid to solid, solid to liquid
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Purdue University
Non-Alcoholic Fatty Liver Disease
Effect of Molecular Hydrogen in Patients With NAFLD
Molecular hydrogen H2 acts as antioxidant which selectively reduces cytotoxic harmful reactive oxygen species ROS and concomitantly acts as biological messenger, which mediates several signaling pathways that play cytoprotective…
- Trial name
- EMoHyNAFLD (NCT05325398)
- Testing
- HRW drink, HRW Natural Health Products Inc., Made in Vancouver, Canada
- Where
- Slovakia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Comenius University
Cardiometabolic Syndrome, Glucose Metabolism Disorders
The Effect of Flexitarian, Time-restricted Eating on Cardiometabolic Traits in Normal Weight, Young Men
The goal of this factorial randomized controlled trial is to find out whether time-restricted eating and flexitarian diet (on its own and combined) can improve cardiometabolic health markers in normal weight, young men with…
- Conditions
- Cardiometabolic Syndrome, Glucose Metabolism Disorders, Blood Pressure, Lipid Metabolism Disorders
- Trial name
- FlexiFast (NCT05762263)
- Testing
- Dietary
- Where
- Poland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Cardiovascular Diseases, Nephropathy
Effect of the Aquaretic Tolvaptan on Nitric Oxide System (TORA)
The purpose of this study is to investigate the effect of tolvaptan on renal water, sodium and potassium excretion, plasma concentration of vasoactive hormones,central blood pressure, pulse wave velocity (PWV) and augmentation…
- Trial name
- NCT01638663
- Testing
- Tolvaptan
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Healthy Volunteers
A Comparative Study on Local Allergic Responses of Bee Venom and Essential Bee Venom Pharmacopuncture
This double-blinded randomized clinical trial investigates any differences in allergic responses elicited by Bee Venom (BV) and Essential Bee Venom (eBV).
- Trial name
- NCT02364349
- Testing
- Bee Venom (BV), Essential Bee Venom (e-BV)
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water
Hypothermia Rewarming With Distal Limb Warming
The study will compare the rewarming effectiveness of heat donation through the distal arms and legs during rewarming of mildly hypothermic subjects.
- Conditions
- Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water, Rewarming by Arm and Leg Exposure to Fluidotherapy
- Trial name
- NCT01827449
- Testing
- Fluidotherapy warming device
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Injuries
Common Recreational Diving Practices: A Randomized Control Trial Using Pre-Dive Checklist
To evaluate the efficacy of using a pre-dive checklist to prevent the incidence of diving mishaps in recreational divers.
- Trial name
- Checklists (NCT01960738)
- Testing
- A pre-dive checklist
- Where
- 4 sites in United States, Cayman Islands and 1 more
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Divers Alert Network
Obesity
Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women
In South Africa the prevalence of obesity in women of reproductive age is high; these women also have a high risk for iron deficiency (ID).
- Trial name
- NCT05220735
- Testing
- Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA)
- Where
- South Africa
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Drug-Drug Interaction, Heathy Volunteer
Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity
Primary objective: 1. To assess the potential inhibitory and inducing effect of oral givinostat on the single dose pharmacokinetics (PK) of intravenous or oral midazolam. 2.
- Trial name
- NCT05492318
- Testing
- Givinostat 10 mg/mL, Midazolam 1mg/ml IV, Midazolam 2.5 mg oromucosal solution
- Where
- Portugal
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Italfarmaco
Cancer, Radiation Therapy
Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer
The purpose of this study is to determine the feasibility of capturing daily dietary intake of patients undergoing radiation therapy using a mobile food record.
- Conditions
- Cancer, Radiation Therapy, Dietary Intake
- Trial name
- NCT07682714
- Testing
- Mobile food record using myCircadian Clock app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Renal Insufficiency
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems
This study is open to people with and without kidney problems. People can join the study if they are 18 years or older and have a body mass index (BMI) between 18.5 and 35 kg/m2.
- Trial name
- NCT05718843
- Testing
- BI 425809
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Length of Hospital Stay
Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries
Surgery is known to be associated with stress response affecting in a negative way the clinical outcome and patient experience. The stress response includes both sympathetic nervous system activation and systemic inflammatory…
- Trial name
- NCT04962776
- Testing
- Low-concentration carbohydrate and nitrates, Low-concentration carbohydrate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Osteoporosis, Postmenopausal, Osteoporosis, Age-Related
Tart Cherry Supplementation and Women's Bone Health Study
In spite of aggressive approaches to prevent and treat osteoporosis, it remains one of the most costly and debilitating diseases associated with aging.
- Trial name
- NCT04167150
- Testing
- tart cherry juice concentrate is a commercial product provided by King Orchards (Central Lake, MI)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Diaper Rash
Effects of Argan Spinosa Oil in the Treatment of Diaper Dermatitis in Infants and Toddlers
The study hypothesized that using the traditional medicinal product of Argan spinosa oil is more effective than conventional topical steroid ointment on the speed up of the healing process and alleviation the symptoms in children…
- Trial name
- NCT04210674
- Testing
- The traditional medicinal product of Argan spinosa oil
- Where
- 3 sites in Jordan
- Volunteers
- 150 people
- Sponsor
- Jordan University of Science and Technology
Scleroderma, Systemic, Graft Vs Host Disease
The Influence of Extracorporeal Photopheresis on Skin Sclerosis
Extracorporeal photopheresis (ECP), also known as extracorporeal photoimmunotherapy or photochemotherapy, is a leukapheresis-based therapy that has been in clinical use for over three decades after receiving FDA approval in 1988.
- Conditions
- Scleroderma, Systemic, Graft Vs Host Disease, Eosinophilic Fasciitis, Morphea
- Trial name
- NCT04752397
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Charite University, Berlin, Germany
Dental Sedation
Intranasal Versus Nebulized Midazolam in Behaviuor Modification of Preschool Children Undergoing Dental Treatment
The aim of the current study is to compare the effect of intranasal versus nebulized route of administration of midazolam as moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT05883150
- Testing
- Nebulized Midazolam, Intranasal Midazolam
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Nourhan M.Aly
Covid19, Physical Disability
Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae.
- Trial name
- NCT04673318
- Testing
- heat therapy, exercise training
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
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