Clinical trials: Water, completed
Gastric Cancer
Prospective Randomized Trial Comparing Gastrectomy, Metastasectomy Plus Systemic Therapy Versus Systemic Therapy Alone: GYMSSA Trial
Background: Gastric (stomach) cancer is a rare cancer. In most cases, by the time it has been diagnosed it has spread to other organs in the body and the chance of a cure is very small.
- Trial name
- NCT00941655
- Testing
- Oxaliplatin, Irinotecan, 5-Fluorouracil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute (NCI)
Subcutaneous Fat
Long-term 24-month Follow-up Study on Safety and Maintenance of Efficacy of ATX-101 (Sodium Deoxycholate Injection)
The objective of this non-treatment, placebo-controlled, observational, 24-month follow-up study was to evaluate the long-term efficacy and safety of subcutaneous (SC) injections of deoxycholic acid (ATX-101) in the submental…
- Trial name
- NCT03682471
- Testing
- Deoxycholic acid Injection
- Where
- 18 sites in Germany
- Volunteers
- 201 people
- Sponsor
- Allergan
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Constipation, Irregular Bowel Movement Frequency
IQP-PO-101 for the Regulation of Bowel Movement Frequency
The purpose of the study is to evaluate the safety and efficacy of IQP-PO-101 in regulating the bowel movement frequency
- Trial name
- NCT01809587
- Testing
- IQP-PO-101
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Healthy Subjects
Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects
This was a single-center study using induced blood stage malaria infection to characterize the activity of ACT-451840 against early Plasmodium falciparum blood stage infection
- Trial name
- NCT02223871
- Testing
- ACT-451840:, Plasmodium falciparum-infected human erythrocytes:, Artemether 20 mg and lumefantrine 120mg combination tablet:
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Stunting, Anemia
Effectiveness Study During the First 1,000 Days in Kenya
Malnutrition is a public health problem in Kenya, with 26% of children underfive years of age stunted, and 26% of pre-school children, 26% of women of reproductive age and 42% of pregnant women being anaemic, respectively.
- Conditions
- Stunting, Anemia, Micronutrient Deficiency
- Trial name
- NCT03558464
- Testing
- Intervention (integrated package), Control
- Where
- Kenya
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Fabian Rohner
Postprandial Hyperglycemia
Determination of the PPG and Insulin Responses of Rice Alone and Rice Consumed With Sugardown™
This study was a partly controlled laboratory-based study comparing the short-term postprandial blood glucose and insulin responses produced by 3 test meals containing white rice alone or with SUGARDOWN™ (Galactomannan) in…
- Trial name
- NCT03375398
- Testing
- Rice, Sugardown™
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Therapeutics
Wound Heal, Scar
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
The pilot study is prospective, randomized, double-blinded, with intra-subject comparisons against a vehicle control. The primary objective of this pilot study is to investigate the safety and effectiveness of a new wound care…
- Conditions
- Wound Heal, Scar, Keloid, Surgical Wound
- Trial name
- NCT04169438
- Testing
- Vehicle Cream Base Emulsion Moisturizer + Petrolatum, FS2 Emulsion Moisturizer + Petrolatum
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Chronic Kidney Failure
Clinical Evaluation of Low Sodium Peritoneal Dialysis (PD) Solution on Hypertensive Patients Treated With PD
The aim of this study is to assess the superiority of the new low sodium peritoneal dialysis (PD) solution PDsol 12 in comparison with a conventional, already marketed solution, Gambrosol trio 40, in the treatment of the…
- Trial name
- PDOne (NCT00794326)
- Testing
- Solution for Peritoneal Dialysis
- Where
- 29 sites in Denmark, France and 3 more
- Volunteers
- 140 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Varicella
An Open-labelled Clinical Trial of Live Attenuated Varicella Vaccines to Evaluate the Immunity Persistence After Primary Immunization and Safety and Immunogenicity After the Booster Immunization
This is an open-labelled clinical trial of live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd .The purpose of this study is to evaluate the immunity persistence of the single-dose…
- Trial name
- NCT05150392
- Testing
- Investigational live attenuated varicella vaccine
- Where
- China
- Volunteers
- 1,193 people, healthy volunteers welcome
- Sponsor
- Sinovac (Dalian) Vaccine Technology Co., Ltd.
Glucose Metabolism, High Altitude
High Altitude and Exogenous Carbohydrate Oxidation
Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders.
- Trial name
- NCT03851744
- Testing
- Sea Level, High Altitude
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Nasolabial Folds
Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
This study has been designed to evaluate the safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the…
- Trial name
- NCT03780244
- Testing
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Multiple Sclerosis, Relapsing-Remitting
Worms for Immune Regulation of Multiple Sclerosis
The purpose of this study is to determine whether people with MS who are exposed to a small number of hookworms will have less inflammation and less MS disease activity.
- Trial name
- WIRMS (NCT01470521)
- Testing
- Hookworm larvae
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Nottingham
Insomnia
Safety and Pharmacokinetic Study of Sublingual Flumazenil (CRLS035) in Healthy Adults
This study compare the pharmacokinetic (PK) profile of sublingual CRLS035 (two doses) to I.V flumazenil administration. Selection of study drug dosage: CRLS035 - sublingual Flumazenil will be administrated at a final dosage of…
- Trial name
- NCT01655914
- Testing
- Flumazenil
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Coeruleus Ltd.
Pharmacokinetics, Inhibition Enzyme
Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1
The purpose of the study is: to determine absolute bioavailability, input rates, distribution volume, renal and intestinal excretion of trospium in subjects with wild-type of SLC22A1 rs72552763 and rs12208357 and in subjects with…
- Conditions
- Pharmacokinetics, Inhibition Enzyme, Drug Interaction Potentiation
- Trial name
- NCT03011463
- Testing
- intravenous infusion of 2 mg trospium chloride, oral administration of 30 mg trospium chloride, oral administration of 300 mg ranitidine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. R. Pfleger Chemische Fabrik GmbH
Osteoarthritis, Knee
The Effect of Cryotherapy in Pain Control, Function and Quality of Life in Individuals With Knee Osteoarthritis
The purpose of this study is to verify the effect of cryotherapy in pain control, function and quality of life in individuals with knee osteoarthritis.
- Trial name
- NCT02725047
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Collagen Synthesis, Rate of Force (RFD) Development
Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance
Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes
- Trial name
- NCT04437758
- Testing
- Collagen and Vitamin C powder mix nutritional intervention, Maximum power training exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Bioequivalence, Healthy Japanese Subjects
Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects
This study will be an open-label, randomised, three-period, three-treatment, crossover study in healthy Japanese male and female of non-childbearing potential subjects, performed at a single study centre.
- Conditions
- Bioequivalence, Healthy Japanese Subjects, Pharmacokinetics
- Trial name
- NCT02436577
- Testing
- Ticagrelor OD tablet (90 mg single dose) administered with 150 mL of water, Ticagrelor OD tablet (90 mg single dose) administered without water, Ticagrelor IR tablet (90 mg) administered with 150 mL of water
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Dengue
Study to Examine the Effects of Oral Fenretinide
This randomized, placebo controlled single center study examines the extent to which 600 mg/m2/day of orally administered ISLA101 (fenretinide), given prophylactically or therapeutically, may reduce or eliminate signs and…
- Trial name
- PROTECT (NCT06528457)
- Testing
- ISLA101, Dengue 1 Live Virus Human Challenge (DENV-1-LVHC)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Island Pharmaceuticals
Healthy
Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2
Purpose: To determine if modulation of NRF2 with a Sulforaphane enriched supplement modifies responses to O3. Participants: Recruitment of up to 70 healthy volunteers, ages 18-50, for completion of 36 volunteers.
- Trial name
- BroccOz (NCT01625130)
- Testing
- Broccoli sprout homogenate, alfalfa sprout homogenate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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