Clinical trials: immunohistochemistry staining method, completed
Carcinomatosis, Peritoneal, Pancreas Cancer
Characterization of Biophysical Stromal Properties in Human Cancer: Towards Personalized Computational Oncology
Drug delivery in solid tumors, whether administered systemically or locoregionally, is hindered by an elevated interstitial fluid pressure (IFP).
- Conditions
- Carcinomatosis, Peritoneal, Pancreas Cancer, Ovarian Cancer, Colon Cancer
- Trial name
- DCE-MRI (NCT04512209)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Ghent
Vitiligo
Exosomal Markers CD63 and CD9 in Vitiligo Before and After NB-UVB Therapy
This study evaluated the expression of the exosomal markers CD63 and CD9 in the skin of patients with vitiligo and assessed changes in their expression after narrow-band ultraviolet B (NB-UVB) therapy.
- Trial name
- NCT07796893
- Testing
- Narrow-Band Ultraviolet B (NB-UVB) Therapy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Amany El-Agamy Ibrahim El-Samadony
Breast Cancer, Inflammatory Breast Cancer
MUC1 Vaccine for Triple-negative Breast Cancer
RATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells. Giving booster vaccinations may make a stronger immune response and prevent or delay the recurrence of cancer.
- Conditions
- Breast Cancer, Inflammatory Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT00986609
- Testing
- MUC-1 peptide vaccine, poly ICLC, MUC1 peptide-poly-ICLC adjuvant vaccine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Joseph Baar, MD, PhD
B-cell Chronic Lymphocytic Leukemia, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma
This phase I trial is studying the side effects of giving genetically engineered lymphocytes together with cyclophosphamide and aldesleukin in treating patients with relapsed or refractory mantle cell lymphoma or indolent B-cell…
- Conditions
- B-cell Chronic Lymphocytic Leukemia, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma, Recurrent Grade 1 Follicular Lymphoma
- Trial name
- NCT00621452
- Testing
- therapeutic autologous lymphocytes, cyclophosphamide, aldesleukin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Fred Hutchinson Cancer Center
Leukemia
Analysis of Blood and Bone Marrow to Detect Residual Disease in Patients With Previously Treated Hairy Cell Leukemia
RATIONALE: Diagnostic procedures that detect residual disease may predict disease relapse in patients who have hairy cell leukemia.
- Trial name
- NCT00005619
- Testing
- polymerase chain reaction, flow cytometry, immunohistochemistry staining method
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Breast Cancer
Gene Expression Following Short Term Exposure to Neoadjuvant Endocrine Therapy in Invasive Breast Cancer
The purpose of this pilot study is to see if taking anastrozole (Arimidex) for 10 days causes changes in breast cancer cells. Anastrozole (Arimidex) is a drug used in the treatment of a type of breast cancer that depends on…
- Trial name
- NCT00588003
- Testing
- anastrozole
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cancer
A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma
To compare the Idylla microsatellite instability test versus mismatch repair immunohistochemistry (IHC) in gastric adenocarcinoma.
- Trial name
- NCT04232020
- Testing
- Mismatch repair
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Cornwall Hospitals Trust
Head and Neck Cancer
Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules
RATIONALE: Finding genetic markers for thyroid cancer in a biopsy specimen may help doctors diagnose thyroid cancer. PURPOSE: This clinical trial is studying how well genetic analysis works in diagnosing thyroid cancer in…
- Trial name
- NCT00316823
- Testing
- gene expression analysis, polymerase chain reaction, reverse transcriptase-polymerase chain reaction
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of California, San Francisco
Breast Cancer
S9313B Study of Tumor Tissue Samples From Women With Early-Stage Breast Cancer Enrolled on Clinical Trial SWOG-9313
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00949013
- Testing
- immunohistochemistry staining method, laboratory biomarker analysis
- Volunteers
- 1,600 people
- Sponsor
- SWOG Cancer Research Network
Lung Cancer, Precancerous Condition
Studying Genes in Blood and Lung Fluid Samples From Patients With Chronic Obstructive Pulmonary Disease With or Without a Previous Diagnosis of Lung Cancer or With Asthma Treated With Budesonide and Formoterol
RATIONALE: Studying the genes expressed in samples of blood and lung fluid in the laboratory from patients receiving budesonide and formoterol may help doctors learn more about the effect of budesonide and formoterol on gene…
- Trial name
- NCT00569712
- Testing
- budesonide/formoterol fumarate dihydrate inhalation aerosol, DNA methylation analysis, comparative genomic hybridization
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- British Columbia Cancer Agency
Pancreatic Adenocarcinoma
HER-2 Expression in Pancreatic Duct Adenocarcinoma
Pancreatic duct adenocarcinoma is a highly aggressive carcinoma that is associated with a poor prognosis. Detection of novel biological markers that are specifically over expressed in pancreatic duct adenocarcinoma and their…
- Trial name
- NCT06055647
- Testing
- immunohistochemical approach
- Volunteers
- 37 people
- Sponsor
- Sohag University
Histopathology, Wrinkle
Open Label Study Exploring Tissue Histopathology After Ellacor® Procedure in an Abdominoplasty Model.
The goal of this study to better understand how the ellacor® Micro-Coring™ procedure works using an abdominoplasty, or tummy tuck surgery, model.
- Conditions
- Histopathology, Wrinkle, Rhytides
- Trial name
- NCT06421207
- Testing
- ellacor® Micro-Coring procedure
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Sarcoma
Protein Expression in Samples From Young Patients With Rhabdomyosarcoma
RATIONALE: Studying tissue samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01426945
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Volunteers
- 77 people
- Sponsor
- Children's Oncology Group
Colorectal Cancer
WT1 in Colorectal Adenocarcinoma
Colorectal carcinoma is a major bublic health problem. It is due to several genetic mutations. Wilms' tumor1 (WT1) gene is a tumor suppressor gene that has been mutated in several human tumors.
- Trial name
- NCT07778628
- Testing
- immunohistochemical staining with WT1 antibody
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Endometrial Cancer
Ridaforolimus in Treating Patients With Recurrent Metastatic and/or Locally Advanced Endometrial Cancer
RATIONALE: Ridaforolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00770185
- Testing
- ridaforolimus, gene expression analysis, immunohistochemistry staining method
- Where
- 11 sites in Canada
- Volunteers
- 35 people
- Sponsor
- NCIC Clinical Trials Group
Breast Cancer
Studying Blood Samples in Women With Breast Cancer or a History of Breast Cancer
RATIONALE: Studying samples of blood in the laboratory from patients with current or previous cancer may help doctors learn more about biomarkers related to cancer.
- Trial name
- NCT00898703
- Testing
- flow cytometry, immunoenzyme technique, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Chronic Urticaria
Real-world Evaluation of the Effectiveness of Immunoglobulin-Histamine Complex, IHC (Histoglob) in Chronic Urticaria
This is a prospective, multicentre, non-interventional, observational, real-world evidence (RWE) study designed to evaluate the effectiveness and safety of Immunoglobulin/Histamine Complex (IHC) in patients with Chronic Urticaria…
- Trial name
- RUSH (NCT07680413)
- Testing
- Antihistaminics, H2 blockers, Leukotriene antagonists, Immunoglobulin/Histamine Complex (IHC) Injection
- Where
- 40 sites in India
- Volunteers
- 660 people
- Sponsor
- Bharat Serums and Vaccines Limited
Lung Cancer
Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous Treatment
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00673569
- Testing
- erlotinib hydrochloride, gene expression analysis, protein expression analysis
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Primary Soft-tissue Sarcoma
A Microdose Evaluation Study of ABY-029 in Primary Sarcoma
The primary study objective is to determine if microdoses of ABY-029 (up to 6X) lead to detectable signals (defined as signal-to-noise ratio, SNR ≥10, with the Odyssey NIR scanner in sampled tissues with an EGFR pathology score ≥…
- Trial name
- NCT03154411
- Testing
- ABY-029
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lymphoma
SWOG-8819 Collecting, Analyzing, and Storing Tissue Samples From Patients With Non-Hodgkin's Lymphoma
RATIONALE: Collecting and storing samples of tissue from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00900484
- Testing
- biologic sample preservation procedure, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- 191 sites in United States
- Volunteers
- 458 people
- Sponsor
- SWOG Cancer Research Network