Clinical trials: rTMS
Spasticity
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
Spasticity is a common complication of stroke affecting quality of life. Spasticity involves exaggerated stretch reflexes that create stiffness in muscles with associated loss of motion and functional control.
- Trial name
- NCT02268461
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Minnesota
Parkinson's Disease, Depression
rTMS for Motor and Mood Symptoms of Parkinson's Disease
The purpose of this study is to determine if repetitive transcranial magnetic stimulation (rTMS), a method of noninvasive brain stimulation) is effective in the treatment of the motor (movement) and mood symptoms due to…
- Trial name
- MASTER-PD (NCT01080794)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 6 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Beth Israel Deaconess Medical Center
Parkinson Disease With Freezing of Gait
Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait
Freezing of gait (FoG) is a common and debilitating condition in Parkinson's Disease (PD) patients. FoG is described as an episodic inability to walk, which often triggers falls, hospitalization and is an important predictor of…
- Trial name
- TMS/FOG (NCT03273270)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804270
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Paul E. Croarkin
Parkinson's Disease, Musculoskeletal Pain
Repetitive Transcranial Magnetic Stimulation for Musculoskeletal Pain in Patients With Parkinson's Disease
Pain is an increasingly recognized non-motor symptom of Parkinson's disease (PD), with significant prevalence and negative impact on the quality of life of patients.
- Conditions
- Parkinson's Disease, Musculoskeletal Pain, Repetitive Transcranial Magnetic Stimulation, Primary Motor Cortex
- Trial name
- NCT05537597
- Testing
- active M1-rTMS
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Stroke
Premotor Cortex: A New Target for Stroke Motor Rehabilitation
The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.
- Trial name
- NCT02565199
- Testing
- rTMS Over Contralateral Hemisphere of Premotor Cortex, rTMS Over Ipsilateral Hemisphere of Premotor Cortex, Control 1: rTMS Timed 400 ms After Movement-related EMG
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Emory University
Nicotine Use Disorder, Nicotine Dependence
Accelerated rTMS for the Reduction of Nicotine Craving
The purpose if this study is to determine if five treatments of repetitive transcranial magnetic stimulation (rTMS) can reduce craving for cigarettes in smokers.
- Trial name
- NCT03352609
- Testing
- Active rTMS with MagVenture MagPro double blind rTMS system
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Epilepsy
fMRI Guided TMS Enhancement of Associative Memory Networks
This is a randomized, single-blinded, controlled phase 1 study to demonstrate feasibility and explore the neurophysiologic and clinical effects of repetitive transcranial magnetic stimulation (TMS) interventions in epilepsy…
- Trial name
- NCT02749422
- Testing
- MagStim RapidStim2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hoarding Disorder, Hoarding
Neuromodulation for Comorbid Hoarding Disorder and Depression
The primary goal of this study is to evaluate whether intermittent theta burst stimulation (iTBS) is effective for treating depression in people who have depression and chronic hoarding disorder (HD).
- Conditions
- Hoarding Disorder, Hoarding, Depression
- Trial name
- NCT05985356
- Testing
- iTBS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
Efficacy and Mechanism of rTMS in Children With ASD: an Open-label Clinical Trial(Ⅱ)
This study is a open-label clinical trial involving over 30 ASD children aged ≥4 years old. During the study, subjects received repeated transcranial magnetic stimulation (rTMS) intervention on the left primary motor cortex (M1)…
- Trial name
- NCT05472870
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Stroke, Motor Function
Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients
In this study investigator's aim to assess the effect of a type of non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) in conjunction with fluoxetine on motor recovery after stroke.
- Trial name
- NCT02208466
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS), Fluoxetine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Spaulding Rehabilitation Hospital
Amygdala Activation
Effects of Connectivity-based rTMS and State-Dependency on Amygdala Activation
Posttraumatic stress disorder (PTSD) is a highly debilitating disease with response rates to pharmacological treatment rarely exceeding 60%.
- Trial name
- ConnecTMS (NCT03746405)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Traumatic Brain Injury
rTMS to Improve Cognitive Function in TBI
This project will study 40 Veterans identified with symptoms understood to characterize mild to moderate Traumatic Brain Injury (TBI) including Post Traumatic Stress Disorder (PTSD).
- Trial name
- rTMSTBI (NCT02152540)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Healthy, Chronic Pain
H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil
Chronic pain is a serious public health problem with estimates as high as nearly half of the adult population experiencing some form of pain that lasts for more than 6 months.
- Conditions
- Healthy, Chronic Pain, Opioid Use, Pain, Chronic
- Trial name
- NCT04203199
- Testing
- Real rTMS to the mPFC using H7 Coil, Real rTMS to the dlPFC using H1 Coil
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Parkinson's Disease
rTMS for the Treatment of Freezing of Gait in Parkinson's Disease
This study is a double blind comparative study examining the effectiveness of the rTMS treatment on Freezing of Gait (FOG) in patients with Parkinson's disease (PD).
- Trial name
- NCT03219892
- Testing
- High-frequency rTMS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Schizophrenia
A Double-Blind Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Negative Symptoms in Schizophrenia
There is pilot data to suggest the therapeutic value of rTMS applied to the left prefrontal cortex in the treatment of negative symptoms.
- Trial name
- rTMS (NCT00168311)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- The Alfred
Stroke
Improving Rehabilitation by Magnetic Brain Stimulation
We hope to understand the properties of the motor cortex in the brain of people with stroke using non-invasive magnetic stimulation.
- Trial name
- NCT00636701
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Schizophrenia, Schizoaffective Disorder
Treatment of Negative Symptoms of Schizophrenia With Transcranial Magnetic Stimulation (TMS)
This study will test whether repetitive transcranial magnetic stimulation (rTMS) is helpful in treating negative symptoms and social deficits of schizophrenia.
- Trial name
- NCT00517075
- Testing
- Transcranial Magnetic Stimulation (TMS), repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Anxiety, Fear
Effect of rTMS on Anxiety
Given the overall lack of treatment adherence/efficacy, side effects of drugs, and the substantial burden of anxiety disorders on the individual and on the national healthcare system, there is a critical need for mechanistic…
- Conditions
- Anxiety, Fear, Anxiety and Fear
- Trial name
- NCT03993509
- Testing
- rTMS to the right dlPFC
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania