Clinical trials: rTMS, open to volunteers
Treatment Resistant Depression (TRD)
Neuronavigated aiTBS for TRD
The purpose of this study is to confirm the efficacy of two recently introduced repetitive transcranial magnetic stimulation (rTMS) interventions - accelerated intermittent theta-burst stimulation (aiTBS) and individualized…
- Trial name
- NCT07329153
- Testing
- aiTBS
- Where
- 3 sites in United States
- Volunteers
- 247 people
- Sponsor
- University of Texas Southwestern Medical Center
Breast Cancer Females
Effects of Prolonged Continuous Theta Burst Stimulation in Chemotherapy-induced Peripheral Neuropathy
Laboratory studies have shown that prolonged continuous theta burst stimulation (pcTBS) provides better pain relief than 10 Hz repetitive transcranial magnetic stimulation (rTMS), with a shorter stimulation time, making it more…
- Trial name
- CIPN (NCT07151963)
- Testing
- prolonged continuous TBS, 20 Hz rTMS
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Sleep Wake Disorders, Lung Transplantation
Low-Frequency rTMS for In-Hospital Sleep Disturbance After Lung Transplantation
This randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve in-hospital sleep quality in adult lung transplant recipients during early…
- Trial name
- TMS-SLEEP-LTx (NCT07796425)
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 152 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cortical Excitability, Healthy
Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation
This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain activity, and whether combining them produces…
- Conditions
- Cortical Excitability, Healthy, TMS, Menstrual Cycle
- Trial name
- NCT07635017
- Testing
- Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Stroke
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA.
- Trial name
- NCT07113990
- Testing
- Active EA, Active rTMS
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Jing Tao
Bipolar Depression, Bipolar Disorder
Theta-Burst Stimulation for Bipolar Depression
The purpose of this trial is to determine if intermittent theta-burst stimulation (iTBS) can reduce the symptoms of depression in treatment-resistant bipolar disorder.
- Conditions
- Bipolar Depression, Bipolar Disorder, Treatment- Resistant Bipolar Disorder, Type 2 Bipolar Disorder
- Trial name
- TRIBE (NCT06370988)
- Testing
- iTBS Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 124 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Disorder
Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD
Tobacco use is the number one preventable cause of the death in the United States, and is high among US Veterans, and those who have experienced trauma are more likely to smoke.
- Trial name
- TMS-STOP (NCT05723588)
- Testing
- active repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation, nicotine replacement therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Neuromuscular Diseases
The Neuroimage Study of the Neuromuscular Disorders.
The neuromuscular disorders could be briefly divided to neuropathy, myopathy, motor neuron disease, and neuromuscular junction disorder. In the past, the evaluation of the neuromuscular disorders depended on several ways (ex.
- Trial name
- NCT05048862
- Testing
- Neuromuscular ultrasound, Muscle MRI, Nerve conduction studies and autonomic function tests
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injuries (SCI)
Combined TMS-tSCS for Lower Limb Rehabilitation in Chronic Incomplete SCI
he goal of this clinical trial is to learn if combined brain and spinal cord stimulation using TMS-tSCS can improve leg strength and walking recovery in adults with chronic incomplete spinal cord injury.
- Trial name
- NCT07595497
- Testing
- Transcranial Magnetic Stimulation, Transcutaneous Spinal Cord Stimulation
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- National University Hospital, Singapore
Stroke
Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke
Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited.
- Trial name
- NCT01855633
- Testing
- Traditional Theta burst stimulation (TBS), Modified TBS rTMS
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Dongtan Sacred Heart Hospital
Insomnia Chronic, Subjective Cognitive Decline (SCD)
Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment of Insomnia with Subjective Cognitive Decline
Insomnia is the most common form of sleep disorder, and subjective cognitive decline (SCD) in patients with insomnia may be an ultra-early manifestation of AD.
- Trial name
- NCT06710652
- Testing
- rTMS
- Volunteers
- 66 people
- Sponsor
- Fujian Medical University Union Hospital
Attention-Deficit/Hyperactivity Disorder (ADHD)
Finding Alternatives to Standard Treatment for Attention-Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is characterized by poor attention, impulsivity, hyperactivity and emotional-motivational dysregulation.
- Trial name
- FAST-ADHD (NCT04532190)
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Posttraumatic Stress Disorder (PTSD)
Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)
This study is testing a personalized form of brain stimulation called PrTMS as a treatment for post-traumatic stress disorder (PTSD) in military service members and veterans.
- Trial name
- NCT07526285
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Treatment of Resistant Depression, H1-Coil
Theta Burst Stimulation With an 8-Coil Versus H1-Coil for Resistant Depression
The goal of this clinical trial is to compare response rates after treatment with Figure Eight-Coil TMS versus H-Coil TMS on the prefrontal cortex left dorsolateral, in patients suffering from depression resistant.
- Conditions
- Treatment of Resistant Depression, H1-Coil, Theta Burst Stimulation
- Trial name
- rTBShTBS (NCT06813313)
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 108 people
- Sponsor
- Dominique JANUEL
Obsessive - Compulsive Disorder
Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy.
- Trial name
- NCT07146438
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Supportive Therapy (ST), Exposure and Response Prevention (ERP) Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Adam Frank
Multiple Sclerosis
Repetitive Transcranial Magnetic Stimulation (rTMS) in MS Induced Spastic Paraparesis
Study the impact of rTMS on walking ability in people with Multiple Sclerosis (MS) induced spastic paraparesis and moderate walking disability.
- Trial name
- CeV (NCT07159789)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Clinique Neuro-Outaouais
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke, Depression - Major Depressive Disorder
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in…
- Conditions
- Stroke, Depression - Major Depressive Disorder, Walking Impairment
- Trial name
- RESTORATION (NCT07050355)
- Testing
- rTMS, AEx
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Medical University of South Carolina
Stroke, Transcranial Magnetic Stimulation
Individualized rTMS for Motor Recovery in Stroke Patients
This study aimed to aim to investigate the efficacy of individualized rTMS according to lateralization index on motor recovery and cortical excitability in subacute stroke patients.
- Trial name
- NCT05914038
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital