Clinical trials: rTMS
Chronic Tinnitus
Combined Transcranial and Peripheral Muscle Magnetic Stimulation in Chronic Tinnitus
Magnetic stimulation of the brain (repetitive transcranial magnetic stimulation) and of neck muscles (repetitive peripheral muscle stimulation) is used to alter tinnitus-related cortical activity and neck muscles tension.
- Trial name
- rpms-tinn (NCT02306447)
- Testing
- rPMS and rTMS
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University of Regensburg
Depression
Antidepressant Mechanisms of Transcranial Magnetic Stimulation
This study utilizes resting state fMRI, arterial spin labelling imaging, diffusion tensor imaging, structural MR-imaging, and MR-spectroscopy of GABA and Glutamate to probe the antidepressant mechanisms of repetitive transcranial…
- Trial name
- NCT02466230
- Testing
- Repetitive transcranial magnetic stimulation
- Volunteers
- 28 people
- Sponsor
- Weill Medical College of Cornell University
Fecal Incontinence (FI), Healthy Female Volunteer
Dose-Efficacy of rTMS in Healthy Young Female Volunteers
This study is aimed to develop a new therapy based on non-invasive repetitive magnetic stimulation rehabilitation for FI in patients who do not respond to conventional therapies.
- Trial name
- NCT07192328
- Testing
- rTMS and rTLSMS administered using a Magstim Rapid2 repetitive stimulator at pre-identified hotspots (cortical, lumbar, and sacral regions bilaterally).
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital de Mataró
Chronic Migraine, Medication Overuse Headache
Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migraine With Medication Overuse
This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy of non-invasive brain stimulation as an add-on treatment to standard detoxification therapy in patients with chronic migraine and…
- Trial name
- NCT07442916
- Testing
- Active rTMS Motor Cortex Face, Active rTMS - Motor Cortex Forearm
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation.
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT05276050
- Testing
- active F8-coil delivered rTMS, active H-coil delivered rTMS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Relief
Daily Sessions of rTMS to the Left DLPFC Modulate the Pain Thresholds and CPM
The main purpose of the study is to assess whether repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex main boost the pain thresholds.
- Trial name
- NCT03733015
- Testing
- repetitive transcranial magnetic stimulation
- Where
- 2 sites in Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Lumbar Radiculopathy
Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain
The present study aims to compare directly the efficacy of two noninvasive neurostimulation techniques : repetitive transcranial magnetic stimulation and transcranial direct electrical current of the motor cortex in patients with…
- Trial name
- NCT02030626
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Ambroise Paré Paris
Cerebellar Ataxia
rTMS for Cerebellar Ataxia in Children
Dysfunction of the cerebellum can result in cerebellar ataxia (CA), typically marked by symptoms such as movement incoordination, gait instability, articulation disorder, oculomotor and swallowing difficulties.
- Trial name
- rTMS CA (NCT07211490)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Alzheimer Disease, Primary Progressive Aphasia
Network Modulation in Alzheimer's Disease
The purpose of this study is to assess the effects of non-invasive brain stimulation on memory and language ability in patients with two phenotypic variations of underlying Alzheimer disease pathology: amnestic mild cognitive…
- Conditions
- Alzheimer Disease, Primary Progressive Aphasia, Mild Cognitive Impairment
- Trial name
- NCT04045990
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Stroke, Motor Function
Effects of rTMS and tDCS on Motor Function in Stroke
In this study the investigators aim to investigate the effects of two different types of non-invasive brain stimulation techniques -- repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation…
- Trial name
- NCT01574989
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Multiple Sclerosis
Improving Hand Movement and Coordination in People With Multiple Sclerosis Using Transcranial Magnetic Stimulation (TMS) and Muscle Electrostimulation (FES) To Support Manual Dexterity and Daily Function
The goal of this interventional study is to test whether combining transcranial magnetic stimulation (TMS) with functional electrical stimulation (FES) can improve hand and upper limb function in adults with Multiple Sclerosis…
- Trial name
- MANTRAStim (NCT07098273)
- Testing
- TMS and FES- based rehabilitation, FES-based rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cancer of Head and Neck, Breast Cancer
Brain Stimulation For Cancer Smokers
Smoking cessation and relapse prevention represent and important opportunity to improve cancer survival rates, reduce the risk of cancer treatment complication, and improve the quality of life of patients with and survivors of…
- Conditions
- Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
- Trial name
- NCT03419741
- Testing
- Transcranial Magnetic Stimulation Clinical Research System
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Chronic Stroke
Repetitive Transcranial Magnetic Stimulation Associated With Physical Therapy to Reduce Upper Limb Spasticity in Post Stroke Patients
In this study, it is being investigated if the association between high frequency repetitive transcranial magnetic stimulation associated with motor physical therapy reduces spasticity, increases upper limb motor function, and…
- Trial name
- NCT03481179
- Testing
- TMS, Physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Depressive Disorder, Adolescent
Development and Application of Comprehensive Intervention Techniques for Adolescent Depression
In order to realize the early identification, risk warning and comprehensive intervention of adolescent depression, this project carried out research on the diagnosis platform of adolescent depression, the construction of suicide…
- Trial name
- NCT05945342
- Testing
- Escitalopram, Interpersonal Psychotherapy for Adolescent, Escitalopram combined with psychotherapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy
Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response
Every year, approximately 2 million people in the United States and 280,000 in Canada experience a mild traumatic brain injury/concussion.
- Conditions
- Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy, Post-Concussion Syndrome, Concussion
- Trial name
- NCT04568369
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Calgary
Fibromyalgia
Repetitive Trans-cranial Magnetic Stimulation of the Motor Cortex in Fibromyalgia: A Study Evaluating the Clinical Efficiency and the Metabolic Correlate in 18FDG-PET
Fibromyalgia (FM) syndrome is a chronic pain condition.Repetitive trans-cranial magnetic stimulation (rTMS) was thus suggested in this indication.
- Trial name
- NCT00697398
- Testing
- Transcranial stimulation
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Depressed Mood
ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
This study will evaluate the feasibility and clinical utility of developing predictive models of treatment response for patients with depressed mood using multimodal clinical data collected in real-world clinical settings.
- Trial name
- ATLAS-1 (NCT07528014)
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Salma Health, Inc.
Advanced Parkinson's With Dysphagia
The Effect of High Frequency rTMS on Advancing Parkinson's Disease With Dysphagia
This study aims to assess the therapeutic role of rTMS on parkinson's patients with dysphagia. Thirty PD patients with dysphagia using UK bank criteria for PD will recruited from outpatient clinic in Assuit University.
- Trial name
- NCT03317509
- Testing
- repetitive transcranial magnetic (rTMS)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Methamphetamine Abuse
A Pilot Study of Repetitive Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorders
We propose a single-arm clinical trial, with historical controls as a comparison group for select outcomes. Subjects with MAUD will receive 16 sessions of dual-target theta burst stimulation to the DLPFC and MPFC over 4 weeks.
- Trial name
- NCT04883021
- Testing
- Dual Target Theta Burst Stimulation
- Where
- United States
- Sponsor
- University of New Mexico
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