Clinical trials: rTMS
Depression, Treatment Resistant
rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression
The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in adults with major depression…
- Trial name
- NCT06511544
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Appetitive Behavior, Obesity
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the…
- Trial name
- NCT06105164
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pain, Visceral Pain
TMS for the Treatment of Pancreatic Cancer Pain
This is a phase II study that aims to investigate prospectively a new therapy for a cohort of patients with chronic pain attributed to pancreatic cancer.
- Conditions
- Pain, Visceral Pain, Pancreatic Cancer
- Trial name
- NCT00324428
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center
Phobia
TMS Augmented Exposure Therapy
This study investigates the beneficial effects of prefrontal brain stimulation (with a facilitating TMS protocol) before exposure therapy in acrophobic patients. The two exposure sessions were realized in virtual reality.
- Trial name
- BEAT (NCT02223767)
- Testing
- Experimental: Verum TMS
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Wuerzburg University Hospital
Methamphetamine Use Disorder
Cerebellum-Prefrontal Paired-Pulse Stimulation for Methamphetamine Use Disorder
To investigate the mechanism and efficacy of a novel repetitive transcranial magnetic stimulation (rTMS) intervention model with paired cerebellar-medial prefrontal cortex (mPFC) pulses on methamphetamine use disorder patients…
- Trial name
- NCT06457230
- Testing
- Paired Associative Stimulation Targeting the Cerebellar-mPFC
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Can Magnetic Brain Stimulation Help Prevent Relapse in Depression?
The purpose of this study is to investigate the use of repetitive transcranial magnetic stimulation (rTMS) in helping to prevent relapse in major depressive disorder.
- Trial name
- NCT02029963
- Testing
- Transcranial Magnetic Stimulation (rTMS), Treatment as Usual
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Stroke
Cerebral Reorganization of Stroke Patients After Repetitive Transcranial Magnetic Stimulation by Neuroimaging Analysis
The study aimed to figure out brain structural and functional reorganization evidence after repetitive transcranial magnetic stimulation through the method of neuroimaging brain network analysis, such as resting-state functional…
- Trial name
- NCT03163758
- Testing
- real Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking Union Medical College Hospital
Depression, Anxiety
Brief, High-dose rTMS for Depression
High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on rational decision trees for dosage determination.
- Trial name
- NCT04657432
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder, Alcohol Use Disorder
Cognitive Dysfunction in the Addictions Study - Project 4 (P4)
The prefrontal cortex, although well established as an efficacious target for the treatment of major depressive disorder (MDD), has recently come into favour as a therapeutic target for alcohol use disorders (AUD).
- Trial name
- CDiA-P4 (NCT06299787)
- Testing
- intermittent theta burst stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Depressive Disorder, Treatment-Resistant
Treatment for Major Depressive Disorder With Intermittent Theta-burst Stimulation
The main purpose of this study is to investigate the two different intermittent Theta Burst (iTBS) repetitive transcranial magnetic stimulation (rTMS), its effectiveness in alleviating depressive symptoms.
- Trial name
- iTBS (NCT05390593)
- Testing
- iTBS-1800, iTBS-1200
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chang Gung Memorial Hospital
Post-stroke Depression
rTMS as an add-on Therapy in Patients With Post-stroke Depression
About 50% of all stroke patients develop post-stroke depression (PSD). A meta-analysis has shown that rTMS treatment can reduce depressive symptoms in PSD patients.
- Trial name
- NCT03761303
- Testing
- active rTMS
- Where
- Germany
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Logopenic Variant Primary Progressive Aphasia, Non-Fluent Primary Progressive Aphasia
rTMS as a Treatment for PPA
Primary progressive aphasia (PPA) includes three variants. Two such variants, the non-fluent/agrammatic variant (nfvPPA) and the logopenic variant (lvPPA), are characterized by progressive word-finding difficulties and effortful…
- Trial name
- NCT03406429
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment
Enhancement of Hippocampal Plasticity Using Repetitive Transcranial Magnetic Stimulation
The ultimate goal of this study is to develop non-invasive, painless repetitive transcranial magnetic stimulation (rTMS) protocols to prevent cognitive decline in patients with mild cognitive impairment (MCI) and cognitively…
- Trial name
- NCT03962959
- Testing
- TBS
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Alzheimer's Disease
Enhancing Working Memory in Patients With Early Alzheimer's Disease Through the Use of rTMS
In this study the investigators aim at assessing and then enhancing neuroplasticity in the dorsolateral prefrontal cortex (DLPFC) and working memory - a key function of DLPFC - in patients with mild Alzheimer's disease (AD).
- Trial name
- rTMS-AD (NCT02537496)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
ADHD
A Randomized, Double-blind, Sham-controlled Pilot Study to Evaluate the Treatment Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in College Students With ADHD
This pilot study is a randomized, double-blind, sham-controlled study designed to evaluate the efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in college students with ADHD. A total of 40 subjects will be treated.
- Trial name
- MeRT-USC-009 (NCT03066505)
- Testing
- Active MeRT Treatment
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Wave Neuroscience
Stroke
Stroke Therapy With Brain Oscillation Synchronized Stimulation
This randomized, controlled, double-blind clinical pilot trial investigates the therapeutic potential of a novel personalized therapeutic brain-stimulation protocol in chronic stroke patients with spasticity.
- Trial name
- STROKEBOSS (NCT05005780)
- Testing
- Negative peak triggered 100 Hz triplet burst TMS, 1 Hz rTMS
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Malignancy
rTMS as a Treatment of Visceral Pain Secondary to Malignancy
The purpose of this study is to assess the efficacy of rTMS over primary motor cortex in patients suffering from malignant visceral pain. Thirty four patients were included in the study.
- Trial name
- NCT02092805
- Testing
- Real rTMS(20 Hz, 10 trains, inter train interval 30 sc with total pulses 2000, intensity 80% of motor threshold) daily for 10 consecutive days (5 days/week)
- Volunteers
- 34 people
- Sponsor
- Assiut University
Executive Dysfunction, Poor Exercise Adherence
Neuromodulation for Exercise Adherence
Lack of adherence to an exercise program is a major problem for older Veterans. Several fall prevention programs fail in the home setting due to lack of adherence.
- Trial name
- NCT03733041
- Testing
- Repetitive Transcranial Magnetic Stimulator, Nintendo Wii-Fit exercises
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Personality Disorder, Borderline, Personality Disorder; Unstable
OFC rTMS in Emotionally Unstable and Depressed Patients
Treatment of depression with conventional transcranial magnetic stimulation (rTMS) has shown high evidence using high-frequency left dorsolateral prefrontal cortex (DLPFC) stimulation.
- Conditions
- Personality Disorder, Borderline, Personality Disorder; Unstable, Depression
- Trial name
- ORIENT (NCT04259554)
- Testing
- OFC rTMS
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University of Regensburg
Generalized Anxiety Disorder
rTMS Pilot for Anxiety
The purpose of this study is to evaluate the safety and tolerability of 1 Hz parietal stimulation in anxiety. Our approach will be to administer 1 week of open-label accelerated 1 Hz parietal rTMS (5 days, 8 sessions/day, 600…
- Trial name
- NCT05306977
- Testing
- Open-label accelerated 1 Hz repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pennsylvania
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