Clinical trials: rTMS
Alzheimer Disease
Assessment of Effectiveness and Safety of Transcranial Magnetic Stimulation (rTMS) Combined With Transcranial Direct Current Stimulation (tDCS) in Dementia Treatment in Alzheimer's Disease
Alzheimer's disease is the most common disease responsible for dementia, accounting for 40-70% of all dementia cases. Alzheimer's disease is characterized by a gradual and slow decline in memory and other cognitive functions and…
- Trial name
- NCT04823819
- Testing
- Magnetic Stimulator DuoMag, neuroConn DC-STIMULATOR
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Lodz
Aphasia, Acquired
Effects of rTMS on Brain Activation in Aphasia
This study will investigate the use of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation method, to improve word-finding abilities in Veterans and non-Veterans with chronic language problems…
- Trial name
- NCT03292471
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Phobia
TMS Augmented Exposure Therapy
This study investigates the beneficial effects of prefrontal brain stimulation (with a facilitating TMS protocol) before exposure therapy in acrophobic patients. The two exposure sessions were realized in virtual reality.
- Trial name
- BEAT (NCT02223767)
- Testing
- Experimental: Verum TMS
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Wuerzburg University Hospital
Aphasia
Combining Language Therapy With rTMS in Aphasia
With the present RCT, the investigators aimed at finding an optimal protocol for the neurorehabilitation of chronic post-stroke aphasia by combining two promising methods, ILAT (Intensive language action therapy) and 1-Hz rTMS to…
- Trial name
- ILAT+rTMS (NCT03629665)
- Testing
- Intensive Language-Action Therapy (ILAT), Repetitive navigated Transcranial Magnetic Stimulation during naming training
- Volunteers
- 17 people
- Sponsor
- Paula Heikkinen
Depressive Disorder, Major, Cognitive Impairment
Brain Functional Connectivity Mechanism of Cognitive Flexibility Impairment and rTMS Intervention in Major Depressive Disorder
Major depressive disorder (MDD) often involves cognitive deficits, particularly in cognitive flexibility, which is inadequately addressed by standard antidepressants.
- Trial name
- NCT07161492
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Second Xiangya Hospital of Central South University
Stress Disorders, Post-Traumatic, Brain Injuries
Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach
In Canada, the prevalence of PTSD is approximately 12%, similar to Canadian military personnel. Current treatments for PTSD are limited in efficacy and durability - indicating a dire need for novel interventions in this…
- Conditions
- Stress Disorders, Post-Traumatic, Brain Injuries, Transcranial Magnetic Stimulation, Magnetic Resonance Spectroscopy
- Trial name
- PTSD (NCT03840369)
- Testing
- Repetitive Transcranial Magnetic Stimulation to Right Dorsolateral Prefrontal Cortex, Repetitive Transcranial Magnetic Stimulation to Right Dorsomedial Prefrontal Cortex
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Repetitive Transcranial Magnetic Stimulation (rTMS), Schizophrenia
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cannabis Use and Cognitive Outcomes in Schizophrenia
The high prevalence of cannabis and other substance use disorders are a major barrier to recovery in people with schizophrenia. Moreover, schizophrenia patients have significant deficits in cognitive function, which may be…
- Conditions
- Repetitive Transcranial Magnetic Stimulation (rTMS), Schizophrenia, Cannabis Use Disorder, Cognition
- Trial name
- rTMSCANSZ (NCT03189810)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Weekly Counselling Session
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Stroke
Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke
Transcranial magnetic stimulation for post-stroke upper-body motor deficits.
- Trial name
- NCT02817087
- Testing
- repetitive Transcranial Magnetic Stimulation -On, repetitive Transcranial Magnetic Stimulation -Off
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- David Chiu, MD
Depression - Major Depressive Disorder, Depression Bipolar
Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression
Aim: The purpose of the study is to establish the non-inferiority of right-sided inhibitory 1 Hz stimulation compared to left-sided intermittent theta burst stimulation (iTBS) in unipolar and bipolar depression.
- Trial name
- NCT07026461
- Testing
- repetitive transcranial magnetic stimulation, intermittent theta burst stimulation
- Where
- 2 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Region Örebro County
Parkinson Disease
Exercise and Plasticity in Parkinson Disease
We will study the effects of intensive rehabilitation in PD on plasticity with a multimodal approach. We will define first, whether exercise in PD restores the potentiation of the motor cortex to normal levels with both 5 Hz-rTMS…
- Trial name
- NCT05786261
- Testing
- experimental group MIRT, EEG task rTMS, fMRI
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore
Stroke Sequelae, Chronic Pain
Transcraneal Magnetic Stimulation for Treatment of Non-nociceptive Pain in Chronic Diseases
Background: Chronic non-nociceptive or nociplastic pain and neurological sequelae following stroke are associated with substantial functional impairment and reduced quality of life.
- Conditions
- Stroke Sequelae, Chronic Pain, Fibromyalgia, Long COVID19
- Trial name
- FATMAGPAIN (NCT07888673)
- Testing
- Transcraneal Magnetic Stimulation (rTMS)
- Where
- 2 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Hospital Donostia
Mild Cognitive Impairment, Caregiver Burden
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
This clinical trial is being conducted to see if brain stimulation and brain training together improves cognitive functioning and mood in older adults diagnosed with Mild Cognitive Impairment (MCI).
- Conditions
- Mild Cognitive Impairment, Caregiver Burden, Mental Health Issue, ADL
- Trial name
- rTMS+iVCT (NCT06024473)
- Testing
- rTMS, rTMS+iVCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Arkansas Veterans Healthcare System
Post-stroke, Anxiety
Integrated Rehabilitation in Treating Post-stroke Anxiety
Post-stroke anxiety (PSA) is a common complication of stroke that leads to dysfunction and reduces the quality of life. PSA exacerbates cognitive dysfunction, delays the recovery process, and increases the disability, mortality…
- Trial name
- IRTPA (NCT05147077)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 188 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Major Depressive Disorder
Individualized Targeting and Neuromodulation of Late-Life Depression
An open-label, single-arm, clinical research study about how to make transcranial magnetic stimulation (TMS), an FDA-approved treatment, more effective for patients with late-life depression using fMRI.
- Trial name
- TMS-LLD (NCT04543773)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of New Mexico
Treatment Resistant Depression (TRD)
Neuronavigated aiTBS for TRD
The purpose of this study is to confirm the efficacy of two recently introduced repetitive transcranial magnetic stimulation (rTMS) interventions - accelerated intermittent theta-burst stimulation (aiTBS) and individualized…
- Trial name
- NCT07329153
- Testing
- aiTBS
- Where
- 3 sites in United States
- Volunteers
- 247 people
- Sponsor
- University of Texas Southwestern Medical Center
Bipolar Disorder, Mood Disorder
Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders
This study is designed to evaluate repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for depression. In rTMS, a rapidly changing magnetic field passes through your scalp and skull and generates a small…
- Conditions
- Bipolar Disorder, Mood Disorder, Unipolar Depression
- Trial name
- NCT00001545
- Testing
- Magstim Super Rapid Magnetic Stimulator, Cadwell MES-10
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Mental Health (NIMH)
Tourette Syndrome
Response Inhibition in Tourette Syndrome
Tics are the hallmark symptoms in Tourette Syndrome. Patients with Tourette Syndrome have difficulties controlling unwanted movements.
- Trial name
- NCT03628703
- Testing
- Repetitive TMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Ankle Instability, CAI, Functional Magnetic Resonance Imaging (fMRI)
fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment
Chronic ankle instability (CAI) is a common sports injury that often leads to recurrent injuries and functional deficits. While conventional rehabilitation can restore ankle stability, the underlying neurophysiological mechanisms…
- Trial name
- NCT06971705
- Testing
- repetitive transcranial magnetic stimulation, rTMS, ankle stability training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wuhan University
Stroke, Hemiplegia
Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding
The purpose of this study is to determine whether repetitive transcranial magnetic stimulation (rTMS) over the brain can modulate the binding of neurotransmitter (GABA in this study) to its receptor using the special PET study.
- Trial name
- NCT01819675
- Testing
- Low frequency rTMS, High frequency rTMS
- Where
- South Korea
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
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