Clinical trials: sponsored by ANRS, Emerging Infectious Diseases
HIV Infections, Hepatitis B
Health and Migration Trajectories of Housekeepers in Bamako
In Mali, migration from rural zones is a cultural phenomenon existing since 1970. During the dry season (9 months), an important number of young women leave their villages and migrate towards urban zones to seek for a job.
- Conditions
- HIV Infections, Hepatitis B, Hepatitis C, Tuberculosis
- Trial name
- 2DM2K (NCT05472051)
- Testing
- Community-based healthcare offer provided by an the ARCAD Santé PLUS NGO and integrated into the activities of the ADDAD NGO
- Where
- Mali
- Volunteers
- 644 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Prevention
Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France.
The purpose of this study is to evaluate if offering long-acting injectable cabotegravir (CAB-LA) as an additional HIV prevention choice among oral PrEP-experienced men who have sex with men (MSM) in France can significantly…
- Trial name
- CABOPrEP (NCT06273943)
- Testing
- Cabotegravir Tablets, for oral use., Cabotegravir Extended-Release Injectable Suspension, for intramuscular use., Tenofovir disoproxil/Emtricitabine 300mg/200mg fixed-dose combination tablets, for oral use
- Where
- 8 sites in France
- Volunteers
- 322 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Seropositivity
National Survey About Trajectory and Life Conditions of HIV Trans People in France
TRANS\&VIH is a national survey that will explore condition of vulnerability and trajectory of transgender people living with HIV.
- Trial name
- Trans&VIH (NCT04849767)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 536 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections
Pilot Implementation of HIV Self-testing Delivery in Private Pharmacies Combined to a Respondent Driven Sampling Method to Improve HIV Testing for MSM and TGW in Phnom Penh - ANRS 0100s
The study aims to evaluate the feasibility of HIV self-testing (HIVST) delivery by a private pharmacy network among men who have sex with men (MSM) and transgender women (TGW) recruited through a classic and digital Respondent…
- Trial name
- NCT05745168
- Testing
- OraQuick
- Where
- Cambodia
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Hepatitis C, Drug Use
DRug Use & Infections in ViEtnam - Hepatitis C (DRIVE-C)
The study aims to assess the effectiveness of a model of hepatitis C screening and integrated care, targeting people who inject drugs (PWIDs) in Hai Phong, Vietnam.
- Conditions
- Hepatitis C, Drug Use, Viral Hepatitis C
- Trial name
- DRIVE-C (NCT03537196)
- Testing
- Sofosbuvir 400 mg and Daclatasvir 60 mg, Sofosbuvir 400 mg and Daclatasvir 90 mg, Ribavirin
- Where
- 2 sites in Vietnam
- Volunteers
- 979 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections
Assessment of HIV Remission Upon cART Interruption in Early Treated Individuals Carrying the MHC B35/53Bw4TTC2 Genotype
The aim of the trial is to evaluate in ANRS CO6 PRIMO cohort participants if the presence of the MHC B35 (53) Bw4TTC2 genotype favors the control of HIV infection (defined by a viral load (VL) less than 400 cp/mL) after…
- Trial name
- NCT05482854
- Testing
- Analytical Treatment Interruption (ATI)
- Where
- 30 sites in France
- Volunteers
- 50 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV-1-infection
A HIV Vaccine Trial in Individuals Who Started Antiretrovirals During Primary or Chronic Infection (EHVA T02)
EHVA T02 is an international, phase II, double-blind study to evaluate two experimental arms each compared to placebo control in HIV-1 positive participants to see if either has a clinically relevant impact on viral replication.
- Trial name
- NCT04120415
- Testing
- Vaccine and vedolizumab (Entyvio)
- Where
- 4 sites in France, Switzerland and 1 more
- Volunteers
- 2 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV, Hepatitis C
Inter Cohorts and Clinical Centres Collaborations of Subjects Co-infected With HIV and HCV
The ANRS CO13 HEPAVIH cohort is a prospective and multicentric cohort created in 2005 with the originality to cover two therapeutic domains of key importance, AIDS and hepatitis C.
- Trial name
- CO13Hepavih (NCT03324633)
- Volunteers
- 1,850 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Monkey Pox, HIV Infections
Seroprevalence of Monkeypox Infection Among People Living With HIV and PrEP Users
This is a cohort, non-health product, non-interventional biomedical research, multi-centric, to determine the seroprevalence of mpox infection in the population of people living with HIV and in PrEP users in Ile-de-France and in…
- Trial name
- MonVIP (NCT05922735)
- Testing
- Questionnaire
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Severe Acute Respiratory Infection (SARI), Influenza
Measure of Vaccine Effectiveness to Prevent Hospitalizations for Viral Respiratory Infections in Adults
This study is a prospective, multicentric, observational test negative design study on adults hospitalized for Severe Acute Respiratory Infection (SARI), regardless of their vaccination status.
- Conditions
- Severe Acute Respiratory Infection (SARI), Influenza, COVID-19
- Trial name
- RESPIVAC (NCT05582239)
- Where
- 8 sites in France
- Volunteers
- 2,400 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Seropositivity
Expectation, Motivation and Experience of HIV-patients Regarding Participation to an HIV Cure-related Clinical Trial
Following the ANRS-APSEC survey, AMEP-EHVA T02 is a longitudinal social science study that will explore the experience of people living with HIV (PLWH) who were offered to participate in the European randomized phase II…
- Trial name
- AMEP-EHVA T02 (NCT05280392)
- Testing
- Self-administered questionnaires, Semi-directive individual interviews
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Covid19, Covid19 Drug Treatment
Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection
Coverage Africa is a nested study in the large Anticov platform trial that aims to generate data on new early treatment strategies for mild/moderate COVID-19 patients in resource-limited-settings to reduce the number progressing…
- Conditions
- Covid19, Covid19 Drug Treatment, Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV2 Infection
- Trial name
- COVERAGE-A (NCT04920838)
- Testing
- Nitazoxanide and Ciclésonide, Telmisartan 20Mg Oral Tablet, Paracetamol
- Where
- 2 sites in Burkina Faso, Guinea
- Volunteers
- 600 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Viral Hepatitis B, Viral Hepatitis C
Therapeutic Option for Hepatitis B and C: a French Cohort
The cohort will integrate clinical, genetic, pharmacogenomics, environmental, biomarkers and behavioral data in a large number of patients and will be a leading equipment for crossdisciplinary and translational research on…
- Trial name
- HEPATHER (NCT01953458)
- Where
- France
- Volunteers
- 20,902 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV-1
Prevention of Mother-to-child Transmission of HIV-1 Using a Responsive Intervention
The second visit of the Expanded Programme of Immunization when the child is 2 months old (EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce preventive and therapeutic rescue…
- Trial name
- PROMISE-EPI (NCT03870438)
- Testing
- Lamivudine Oral Solution
- Where
- 6 sites in Burkina Faso, Zambia
- Volunteers
- 1,506 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV-1-infection
Primary Infection Cohort
Open, prospective, multicenter French cohort study enrolling subjects aged of 15 years or more, during or immediately after HIV-1 primary infection.
- Trial name
- PRIMO (NCT03148964)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 2,800 people
- Sponsor
- ANRS, Emerging Infectious Diseases
STI, Hiv
Partner Notification of Sexually Transmitted Infections (STIs) in Testing Centers
Since the 2000s, the incidence of bacterial STIs increases, mainly among men who have sex with men but also among heterosexual men and women with multiple sexual partners.
- Trial name
- Not'IST (NCT04921618)
- Testing
- 2 online self-administered questionnaires on
- Where
- 9 sites in France
- Volunteers
- 2,200 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Psychological Distress, Quality of Life
Prevention of Mental Health Problems Among Persons Without Personal Housing in the Context of the COVID-19 Epidemic
The Covid-19 pandemic is having a great impact on the long-term mental health and well-being. Reports on the levels of psychological distress are concerning.
- Conditions
- Psychological Distress, Quality of Life, Psychosocial Intervention
- Trial name
- RESPOND-FR (NCT05033210)
- Testing
- Psychological First Aid (PFA), Care as Usual (CAU), Doing What Matters in Times of Stress (DWM)
- Where
- 2 sites in France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Drug Use, HCV Infection
A Community-based Intervention Among Active Drug Users in Montpellier
The study aims to assess the effectiveness of a community-based model of HCV mass screening associated with an immediate HCV treatment on the cascade of care among active drug users (DUs) in the city of Montpellier, France.
- Trial name
- ICONE (NCT04008927)
- Testing
- HCV screening, Diagnosis of hepatitis C, HCV treatment
- Where
- France
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Men Who Have Sex With Men, People Living With HIV
HIV Acquisition and Life Course of Born-abroad Men Who Have Sex With Men Living in Ile-de-France: the GANYMEDE Study
In France, men who have sex with men (MSM) born abroad are the most affected population by HIV, in terms of HIV incidence and prevalence of undiagnosed infections.
- Trial name
- GANYMEDE (NCT04684758)
- Testing
- Self-completion of a questionnaire
- Where
- France
- Volunteers
- 1,048 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections, Viral Hepatitis B
Sexual and Reproductive Health (Including PrEP and HBV) for Female Sex Workers in Côte d'Ivoire
The PRINCESSE study will implement a comprehensive package of services in sexual and reproductive health for female sex workers in the region of San Pedro in Cote d'Ivoire, including screening, prevention and treatment for HIV…
- Conditions
- HIV Infections, Viral Hepatitis B, Sexually Transmitted Diseases, Contraception
- Trial name
- ANRS 12381 (NCT03985085)
- Testing
- Comprehensive package of sexual and reproductive health services
- Where
- Côte d’Ivoire
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases