Clinical trials: sponsored by Al-Azhar University
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Deep Bite Malocclusion
Efficacy of Aligners vs ABT and RCOS for Deep Bite Correction: CBCT Study
This prospective clinical trial aims to evaluate the efficacy of clear aligner therapy compared to two different treatment modalities - anterior bite turbos and reverse curve of Spee (RCOS) archwires - for the correction of…
- Trial name
- DB-CBCT (NCT07096401)
- Testing
- Reverse Curve of Spee Archwire, Anterior Bite Turbos, Clear Aligners
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Retainers
Biological Reaction of Direct 3d Printed Retainers
The aim of this study will be to evaluate the biological reaction of direct three dimensional printed retainers. Primary objective is to evaluate bacterial growth and color stability between different thicknesses of 3d printed…
- Trial name
- NCT07098325
- Testing
- retainer with .5 mm thickness, retainer with 1 mm thickness
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Al-Azhar University
Growth Hormone, EndoSeal MTA
Evaluation of the Efficacy of Growth Hormone, EndoSeal MTA Sealer, and Their Combination on Healing of Periapical Pathosis
This study aimed to evaluate the effect of growth hormone, EndoSeal MTA sealer, and their combination on Healing of Periapical Pathosis.
- Conditions
- Growth Hormone, EndoSeal MTA, Periapical Pathosis
- Trial name
- NCT06433375
- Testing
- Growth hormone application, Root canal treatment
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Remineralization Potential, Dentin Caries
Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated…
- Trial name
- NCT07065305
- Testing
- Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland, Beautifil II LS
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Renal Stones, Pediatric Renal Stones
Retrograde Intrarenal Surgery for Renal Stones in Pediatrics: A Prospective Analysis of Feasibility and Outcomes.
it is an interventional single arm study for treating pediatric renal stones≤2cm by FURS and Holmium laser fragmentation.pediatric groups is benig compared for stone free rate, complication rate , success rate.
- Trial name
- RIRS pediatric (NCT07089394)
- Testing
- flexible urs
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Keratoconus
Efficacy of Corneal Cross-Linking (CXL) in the Treatment of Pediatric Keratoconus
This prospective interventional study investigates the efficacy of corneal cross-linking (CXL) in managing progressive keratoconus in pediatric patients.
- Trial name
- NCT07080983
- Testing
- Crosslinking
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Endoscope, Open
Endoscopic Versus Open Lumbar Discectomy in Diabetic Patients
This study aims to compare the endoscopic versus open lumbar discectomy in diabetic patients.
- Conditions
- Endoscope, Open, Lumbar Discectomy, Diabetes Mellitus
- Trial name
- NCT07060846
- Testing
- Endoscopic lumbar discectomy, Open lumbar discectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Type 2 Diabetes
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
The overarching hypothesis of this study is that vildagliptin (vilda) as add on therapy to metformin (met) in Egyptian type 2 diabetic obese patient will produce an equal, if not better, glycemic control and will reduce…
- Trial name
- NCT07077525
- Testing
- Dapagliflozin + Metformin, Vildagliptin + Metformin
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Al-Azhar University
Traumatic Pulp Exposure in Children
Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth
The aim of the study is to evaluate clinical and radiographic effect of nano propolis and nano curcumin as direct pulp capping agents in young permanent teeth. .
- Trial name
- NCT06029023
- Testing
- MTA Cement, propolis nano particle, curcumin nanoparticles
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Birth Outcome, Adverse
Knowledge, Attitudes, and Practices of Operative Vaginal Birth Among Obstetric Providers in Egypt
The goal of this observational study is to evaluate the knowledge, attitudes, and practices of operative vaginal birth among obstetric providers in Egypt.
- Trial name
- NCT06502119
- Testing
- Designed Questionnaire
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Advanced Periodontitis, Stage III Periodontitis
Treatment of Periodontitis by Tulsi Gel
This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis.
- Conditions
- Advanced Periodontitis, Stage III Periodontitis, Stage IV Periodontitis
- Trial name
- NCT06675578
- Testing
- Tulsi gel, Chlorhexidine gel
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Dental Anxiety
Assessment of a Ventriloquist Puppet for Reducing Dental Anxiety in Children
thhe goal of this clinical trial is to assess the effect of ventriloquist puppets to reduce the strees accompined by the dental visit in cgilren .
- Trial name
- Puppets (NCT07034833)
- Testing
- Ventriloquist Puppet Interaction
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Alveolar Bone Resorption
Vertical Ridge Augmentation Using Computer-guided Sandwich Osteotomy Technique
Researcher will introduce the trial to patients and provide full explanation of its aim and benefits in Arabic language. Patients will then be able to have an informed discussion with the researcher.
- Trial name
- RGD (NCT07028606)
- Testing
- Sandwich technique with xenograft, collagen membrane and simultaneous implant placement., Sandwich technique with (RGD), xenograft, collagen membrane and simultaneous implant placement.
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Laparoscopic Cholecystectomy, Postoperative Nausea and Vomiting
Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Nausea and vomiting are some of the most common complaints of patients after any anesthesia, which is often associated with postop-erative pain.
- Trial name
- NCT05988671
- Testing
- normal Saline, Dexamethasone, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Postdural Puncture Headache
Pregabalin in Treatment of Postdural Puncture Headache
Lumbar puncture (LP), often known as a "spinal tap," is a standard medical technique pioneered in the late 1900s by Heinrich Quincke.
- Trial name
- NCT06271486
- Testing
- Pregabalin 75mg, An epidural blood patch (EBP), conservative treatment.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
Vaginal Microbiota and Post-cesarean SSI
The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery.
- Trial name
- NCT06840041
- Testing
- Vaginal swab and culture
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
COPD Received PR, Elderly (People Aged 65 or More)
Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD
The study aimed to identify the effect of early pulmonary rehabilitation in elderly patients with Acute exacerbation (AE) of COPD (AECOPD) in exercise tolerance, dyspnea, sleep quality, fatigue, and time to discharge from…
- Conditions
- COPD Received PR, Elderly (People Aged 65 or More), COPD, COPD Acute Exacerbation
- Trial name
- NCT07020182
- Testing
- physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Cough
Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia
The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.
- Trial name
- MgSO4/DEX (NCT06979141)
- Testing
- Dexmedetomidine, Magnesium sulfate, Lidocaine
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Al-Azhar University
Gamma Knife Radiosurgery, Tectal Plate Gliomas
Gamma Knife Radiosurgery on Tectal Plate Gliomas
This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).
- Trial name
- NCT07015710
- Testing
- Gamma Knife Radiosurgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University