Clinical trials: sponsored by Al-Azhar University
Black Stains
A Crossover Clinical Study to Evaluate the Effect of Chitosan Mouthwash on Recurrence of Black Stains in Pediatric Patients
The goal of this clinical trial is to learn if Chitosan mouthwash works to affect the recurrence of black stains in pediatric patients.
- Trial name
- NCT06714695
- Testing
- Chitosan
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effect on Pulpotomy
Pediatric dentistry has always debated the benefits of vital pulp therapy. AIM: The current study was done to differentiate the histo-pathological findings of MTA versus grape seed extract in primary teeth undergoing pulpotomy as…
- Trial name
- NCT06694064
- Testing
- Pulpotomy, extraction for histologic examination
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Implant Therapy
Effect of Osseodensification on the Peri-implant Condition
The goal of this clinical trial is to evaluate the effects of osseodensification vs. traditional implant site preparation clinically , radiographically, bio-chemically.
- Trial name
- NCT06689969
- Testing
- conventional implant placement method, Osseodensification to implant placement using densah bur kit
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Al-Azhar University
Menstrual Bleeding, Heavy
Evaluation of the Contraceptive Efficacy
Combined oral contraceptives are not the preparation of first choice in breastfeeding women as they may influence the quality and quantity of breast milk.
- Trial name
- NCT06689150
- Testing
- Drospinetta
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Implant
The Effect of Vitamin D and Calcium Supplement on Overall Body Bone Density and Implant Stability in Posterior Maxilla
The aim of the study is to evaluate the effect of Vit D and Calcium administration on allogragt bone maturation radiographically and histomorphometercally in maxillary sinus augmentation in cases of D4 bone density.
- Trial name
- NCT06673485
- Testing
- Patients received vitamin D and calcium supplementation during the healing period, Patients have not received any nutritional supplementation during the healing period.
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Effect of Intravenous or Intrathecal Dexmedetomidine on Bupivacaine Spinal Block in Lower Abdominal Surgery
This study is a comparative study will be carried out after approval by the Local Ethical Committee in Al-Azhar University hospital (Assiut) and after obtaining patients' written informed consent.
- Trial name
- NCT06654531
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Revascularization of Immature Young Permenant Teeth
The Present Study Was Conducted to Evaluate Bioceramic Root Repair Material Versus Bio MTA in Revascularization of Immature Young Permenant Teeth.
The present clinical study wasdirected to evaluate bioceramic root repair material versus Bio MTA in Revascularization of Immature Young Permenant Teeth through: 1.
- Trial name
- NCT06630156
- Testing
- Revascularization of Immature Young Permenant Teeth
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Treatment of Periodontal Intra-bony Defects
The Present Study Was Performed to Evaluate the Efficacy of Lyophilized-PRF in Treatment of Periodontal Intra-bony Defects
The present study will be performed to evaluate the efficacy of lyophilized platelet-rich fibrin alone and combined with nanocrystalline hydroxyapatite in treatment of periodontal intra-bony defects through: 1.
- Trial name
- NCT06625528
- Testing
- open flap debridement
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Genu Varum
Hemiepiphysiodesis by Eight Plate Versus Osteotomy in the Management of Pediatric Coronal Knee Deformities
Coronal angular deformities of lower limb in children are a common finding in pediatric orthopedic surgery.These angular deformities can be idiopathic in origin, or they can emerge secondary to congenital and acquired…
- Trial name
- NCT06630975
- Testing
- Hemiepiphysiodesis, Eight-Plates first described by Stevens are simple to use, Hemiepiphysiodesis by eight Plate
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg
Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering
The aim of this work was to compare the efficacy of intravenous (IV) tramadol versus magnesium sulphate added to 100 ml saline for prevention of shivering associated with spinal anesthesia.
- Conditions
- Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg, Hernia
- Trial name
- NCT06612996
- Testing
- Tramadol, Magnesium sulphate, Saline
- Volunteers
- 180 people
- Sponsor
- Al-Azhar University
Bleeding on Probing, Alveolar Bone Loss
Single vs. Two Implants for Mandibular Overdentures
This study aimed to compare the use of single implants in the symphyseal and parasymphyseal, and two implants were inserted in the canine area bilaterally to assist mandibular complete overdentures regarding clinical evaluation…
- Conditions
- Bleeding on Probing, Alveolar Bone Loss, Mastication, Dental Plaque
- Trial name
- SIMO/TIMO (NCT06599450)
- Testing
- Root form dental implant
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Al-Azhar University
Periodontal Diseases, Obesity, Morbid
Gingival Crevicular Fluid of Adiponectin and Resistin As Predictable Implement in Staging and Grading System of Periodontitis
The goal of this clinical trial is to evaluate the relationship between obesity and gingival crevicular fluid resistin and adiponectin in periodontitis patients as well as assess the effect of non-surgical periodontal therapy on…
- Trial name
- NCT06604013
- Testing
- non-surgical full-mouth periodontal therapy without using adjunct disinfectants, GCF level of adiponectin and resistin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Osteogenesis
Telescoping Nail in Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI) is an autosomal dominant disorder that mainly affects the bones. Bones break easily. The severity may be mild to severe.
- Trial name
- Telescoping (NCT06591546)
- Testing
- Telescoping nail
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Implant Dentistry
Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement
The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.
- Trial name
- NCT06585852
- Testing
- RGD, Xenograft, Split crest technique
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries Arrested
Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into…
- Trial name
- NCT06585436
- Testing
- partial caries removal
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Health Care Utilization, Diet, Healthy
Assessment of the Rate of Oseointegration Surrounding Nano-coated Orthodontic Titanium Miniscrew
The current study was directed to evaluate rate of oseointegration surrounding nano-coated orthodontic titanium miniscrew.The current study will conduct on eighteen Egyptian males orthodontic patients for three months.
- Conditions
- Health Care Utilization, Diet, Healthy, Frey Syndrome
- Trial name
- NCT05898724
- Testing
- Blank group, Silver hydroxyapatite, Zinc oxide
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Discoloration, Tooth
Bleaching Effect of Solo and Combined Kiwi Extract and Ozone and Their Impact on Enamel
ozone therapy has been extensively used in dentistry to manage wounds healing, dental caries, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, plaque and biofilms, root…
- Trial name
- NCT06582069
- Testing
- Bleaching
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Ultrasound Guided, Supraclavicular
Ultrasound Guided Supraclavicular and Infraclavicular Subclavian vs Catheterization in Pediatric
The aim of this study was to compare between ultrasound-guided supraclavicular and infraclavicular approaches for subclavian venous catheterization in pediatric to get clinical practice of rapid, accurate central venous catheter…
- Conditions
- Ultrasound Guided, Supraclavicular, Infraclavicular, Subclavian
- Trial name
- NCT06575491
- Testing
- Ultrasound-guided supraclavicular approach, Ultrasound-guided infraclavicular approach
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Insuffeciency of the Suprarenal Gland
Ultrasonographical of Suprarenal Gland in High Risk Neonates
Observation study The aim is to study the suprarenal blood flow among high-risk neonates and its relation to the risk factors
- Trial name
- USSGneonates (NCT06575504)
- Testing
- Ultrasonographical examination
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Al-Azhar University
Neoplasm Malignant, Colon Cancer Stage 4
Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study
This prospective Phase II study aims to evaluate the efficacy and safety of a modified FOLFOXIRI regimen in the treatment of metastatic colorectal cancer (MCRC).
- Trial name
- NCT06575127
- Testing
- FOLFOXIRI Protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University