Clinical trials: sponsored by Al-Azhar University
Caries,Dental, Caries Active
Anticariogenic Properties of Zamzam Water
The present study aims to evaluate and compare the effect of Zamzam water as mouthwashes in high caries-risk patients regarding: i. Streptococcus mutans (S. mutans) count. ii. Oral pH. After 3 and 6 months interval.
- Trial name
- NCT06538532
- Testing
- Zamzam water
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
BPH With Other Lower Urinary Tract Symptoms
Administration of Tadalafil in Patients With Benign Prostatic Hyperplasia
The aim of the present study is to evaluate the efficacy and safety of once daily administration PDE5 inhibitors, tadalafil for 3 months as anti-inflammatory, antiproliferative and relaxant effects in ED with BPH patients.
- Trial name
- NCT06466369
- Testing
- Tadalafil
- Where
- Egypt
- Volunteers
- 306 people
- Sponsor
- Al-Azhar University
Stricture Ureter
Buccal Mucosal Graft for Onlay Ureteroplasty in the Management of Proximal Ureteral Stricture
Onlay uretroplasty with either grafts or flaps has been attempted by many reconstructive urologists, ln particular buccal mucosa graft (BMG) ureteroplasty has been reported by many centers and has shown its feasibility and safety
- Trial name
- NCT05928364
- Testing
- Buccal mucosa for proximal ureter stricture
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Stress Urinary Incontinence
Long-term Outcomes of Autologous Transobturator Rectus Fascia Sling for Treatment of Female Stress Urinary Incontinence
Autologous transobturator sling placement is associated with excellent short-term results and can be performed on an outpatient basis in most cases, so long-term outcomes needs to be verified.
- Trial name
- NCT05647070
- Testing
- Autologous rectus Fascia TOT
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Stress Urinary Incontinence
Autologous Transobturator Fascia Lata Sling in Treatment of Female Stress Urinary Incontinence
To evaluate the outcome of autologous transobturator fascia lata sling for treatment of female stress urinary incontinence at Al-Azhar university hospitals.
- Trial name
- NCT05646745
- Testing
- Autologous Transobturator Fascia Lata Sling
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Benign Prostatic Hyperplasia
Comparative Study Between Safety and Effectiveness of High Versus Low Power HOLEP
Holmium laser enucleation (HOLEP) has became a standard of treatment of large prostates that indicates surgery. HOLEP is widely used nowadays. Many settings are used but no optimal setting was world wide adopted.
- Trial name
- NCT05678452
- Testing
- HOLEP for treating BPH
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Stricture Urethra
Role of Paclitaxel in Stricture Urethra
Stricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates.
- Trial name
- NCT05678413
- Testing
- DVIU with paclitaxel injection, DVIU
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Periodontal Bone Defects
Minimally Invasive Non-surgical Therapy With or Without Injectable Bone Putty
All periodontitis patients with infra bony pockets to be included in this study will diagnosed as having stage III periodontitis with probing pocket depth (PPD) ≥ 6 mm, and clinical attachment loss (CAL) ≥ 5mm will be treated by…
- Trial name
- NCT06553222
- Testing
- Putty bone - Tricalcium phosphate with Collagen gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Local Anesthetic Complication
Evaluation of the Anti-anaesthetic Effects of Low-Level Laser Therapy on Children's Soft Tissue
Evaluate the effect of the photobiomodulation mode of the diode laser on the anaesthetic area and find the best parameter that would accelerate the withdrawal of anaesthesia.
- Trial name
- laser (NCT06193460)
- Testing
- low-level laser therapy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Spinal Anesthesia, Hip Fractures
Peri-Capsular Nerve Group and Supra Inguinal Fascia Iliaca BLOCK for Analgesia and Ease of Positioning During Neuraxial Anesthesia in Hip Fracture Patients
Severe pain associated with fractured hip often results in difficulty during positioning for spinal anesthesia (SA). Among many regional analgesic techniques, the fascia iliaca compartment block (FICB) is popular among…
- Trial name
- NCT05987254
- Testing
- suprainguinal fascia iliaca block, pericapsular nerve group block
- Where
- 3 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Urinary Calculi
Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi
This is a prospective randomized study to compare endoscopic combined intrarenal surgery and PCNL as modalities of treatment for staghorn stones. In terms of efficacy and safety
- Trial name
- NCT06519812
- Testing
- Combined Intrarenal Surgery and percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Irreversible Pulpitis
Full Pulpotomy Procedure of Permanent Molar Teeth of Adults Using Calcium Silicate-based Sealer Material
This clinical study aims to assess the efficacy of using calcium silicate based sealer as a capping material after complete removal of coronal pulp tissue. The study will evaluate both the clinical and radiographic changes.
- Trial name
- NCT06504108
- Testing
- Calcium silicate-based sealer full Pulpotomy, Calcium silicate-based premixed putty full Pulpotomy, Full Pulpotomy
- Where
- 2 sites in Egypt
- Volunteers
- 78 people
- Sponsor
- Al-Azhar University
Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement
Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors
The aim of this prospective clinical study will be to compare the efficacy of micro osteoperforations versus injectable platelet-rich fibrin during orthodontic leveling and alignment of mandibular incisors.
- Trial name
- NCT06498609
- Testing
- iprf, MOPs with leveling and alignment
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
TADs Anchored vs Conventional Anchored Carriere Motion Appliance
Carriere Motion appliance (CMA) was designed to correct a Class II molar relationship into a Class I relationship by distalizing the whole posterior maxillary segment by means of class II elastics and mandibular anchorage.
- Trial name
- NCT05631353
- Testing
- Carriere Motion Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
TMJ Disorder, TMJ Disc Disorder
Comparison Between Hegab Splint, Arthrocentesis, and Arthroscopy in Treatment of TMJ Closed Lock
This prospective, randomized control study aimed to compare the Clinical Outcome of Hegab splint, Arthrocentesis, and Arthroscopy in treatment of TMJ closed lock.
- Trial name
- arthroscopy (NCT06473376)
- Testing
- arthrocentesis
- Where
- 2 sites in Egypt
- Volunteers
- 45 people
- Sponsor
- Al-Azhar University
NASH - Nonalcoholic Steatohepatitis
Pentoxifylline in Treatment of Patients With Nonalcoholic Steatohepatitis
The aim of the present study is to evaluate the efficacy and safety of pentoxifylline in the treatment of non-alcoholic steatohepatitis patients.
- Trial name
- NCT05284448
- Testing
- pentoxifylline (Trental SR®)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Female Infertility
Extended Culture of Day 3 to Day 5 Frozen Thawed Day 3 Embryos Versus Day 5 Frozen-Thawed Embryos
Cryopreservation of embryos and oocytes has become routine in assisted reproduction technology (ART). Live birth rates following frozen embryo transfers have increased significantly.
- Trial name
- NCT05858333
- Testing
- Extended culture for Group 2: (day 3-5 group)
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cleft Lip and Palate
The Effectiveness of Adhesive Versus Conventional Nasoalveolar Molding on Children With Unilateral Cleft Lip and Palate
The present study will compare the effectiveness of adhesive nasoalveolar molding (GS-NAM) and conventional nasoalveolar molding on the alveolar ridge, nasal, and labial growth in children with unilateral cleft lip and palate.
- Trial name
- NCT06451276
- Testing
- Nasoalveolar molding in unilateral cleft lip and palate
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Irreversible Pulpitis
Evaluation of Using Platelet-Rich Fibrin in Adult Pulpotomy
The goal of this interventional randomized clinical trial is to evaluate the use of platelet rich fibrin in full pulpotomy in mature adult teeth. The main questions it aims to answer are: 1.
- Trial name
- NCT06437197
- Testing
- Pulpotomy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Primary Teeth
Evaluation of Bioflex Crowns Endocrowns Compared to Ready-Made Zirconia Crowns on Pulpotomized Primary Molars
This study will be conducted to evaluate clinical performance, parent's satisfaction, gingival health and bacterial effects of Bioflex crowns \&Endocrowns compared to ready-made zirconia Crowns on Pulpotomized primary molars
- Trial name
- NCT06433141
- Testing
- treatment option for primary second molar
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Al-Azhar University