Clinical trials: sponsored by Alcon Research
Open-angle Glaucoma, Ocular Hypertension
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to assess the comfort of a glaucoma therapy in patients with open-angle glaucoma or ocular hypertension
- Trial name
- NCT00326092
- Testing
- Brinzolamide/Timolol
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to compare the intraocular pressure (IOP)-lowering efficacy and safety of two combination products in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00333125
- Testing
- Travoprost 40 mcg/ml + Timolol 5 mg/ml eye drops, solution (DuoTrav), Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (Cosopt), Timolol Vehicle
- Volunteers
- 319 people
- Sponsor
- Alcon Research
Dry Eye
Barrier Function Measurement in Dry Eye Patients After Using Systane Ultra for 30 Days
The primary objective is to determine if there is a correlation between reductions in corneal staining and improvements in corneal barrier function.
- Trial name
- NCT00946777
- Testing
- Systane® Ultra
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Dry Eye
Evaluation of an Investigational Lubricant Eye Drop on Lipid Layer Thickness
The purpose of this study is to evaluate the effects of an investigational lubricant eye drop on tear film lipid layer thickness of dry eye patients.
- Trial name
- NCT01066988
- Testing
- ORB Ocular Emulsion, SootheXP Emollient (Lubricant) Eye Drops
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Glaucoma
IOP-Lowering Efficacy of Brinzolamide 1.0% Added to Travoprost 0.004%/Timolol 0.5% Fixed Combination as Adjunctive Therapy
Uncontrolled glaucoma patients being treated with a prostaglandin agent alone or in combination with adjunctive drugs in fixed or unfixed combinations, will be switched from their current therapy to travoprost/timolol fixed…
- Trial name
- NCT00382226
- Testing
- Azopt
- Where
- Australia
- Volunteers
- 195 people
- Sponsor
- Alcon Research
Dry Eye
A Clinical Evaluation of an Investigational Lubricant Eye Gel (FID 115958D)
The purpose of this study is to estimate the change in sodium fluorescein staining, as a sign of dry eye, during six weeks of treatment with FID 115958D or Refresh Liquigel.
- Trial name
- NCT01294956
- Testing
- Lubricant Eye Drop, Refresh Liquigel
- Volunteers
- 147 people
- Sponsor
- Alcon Research
Dry Eye Syndrome
In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients
The purpose of this study is to measure corneal epithelial changes in dry eye subjects using a novel lubricant eye gel.
- Trial name
- NCT01483989
- Testing
- SYSTANE® Gel Drop lubricant eye gel
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertension
The purpose of this study is to evaluate the safety and efficacy of BETOPTIC S and Timolol Gel-forming solution in pediatric patients. Patients will dose with study drug at 8 am and 8 pm daily for twelve weeks.
- Trial name
- NCT00061542
- Testing
- BETOPTIC S (betaxolol HCl), Timolol Gel-forming Solution (TGFS)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Alcon Research
Dry Eye Syndrome
Evaluating Safety and Efficacy of FID 112903 Post Discontinuation of Long-term Use of RESTASIS® (Cyclosporine Ophthalmic Emulsion) 0.05%
The purpose of this study is to evaluate the safety and efficacy of FID 112903 given as an immediate treatment replacement in dry eye subjects that discontinue at least 6 months use of RESTASIS.
- Trial name
- NCT01198782
- Testing
- FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops)
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00314158
- Testing
- Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension, Brinzolamide 10 mg/ml (AZOPT) eye drops, suspension, Timolol 5 mg/ml eye drops, solution
- Where
- United States
- Volunteers
- 523 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension
The purpose of this study is to evaluate the safety and efficacy of both BETAXON and AZOPT in pediatric patients. Patients will dose with study drug at 8 am and 8 pm daily for twelve weeks.
- Trial name
- NCT00061516
- Testing
- BETAXON (levobetaxolol HCl), AZOPT (brinzolamide)
- Volunteers
- 78 people
- Sponsor
- Alcon Research
Glaucoma
Success of Transitioning Uncontrolled Glaucoma Patients From Prior Mono or Adjunctive Therapy to DuoTrav
The purpose of this study is to assess the safety and efficacy of transitioning uncontrolled glaucoma patients to DuoTrav from other mono or adjunctive therapies.
- Trial name
- NCT00519753
- Testing
- Travoprost 0.004%/timolol maleate 0.5% fixed combination ophthalmic solution (DuoTrav)
- Where
- Germany
- Volunteers
- 522 people
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of the study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension
- Trial name
- NCT00293761
- Testing
- Travoprost, Investigational, Travoprost (TRAVATAN)
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Ocular Tolerance, Skin Tolerance
A Clinical Study of Systane® Lid Wipes in Brazil
The purpose of this study is to verify the skin and ocular tolerance of the product Systane® Lid Wipes.
- Trial name
- NCT02380261
- Testing
- Systane® Lid Wipes
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataracts
Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo
To evaluate the safety and efficacy of Nepafenac 1 mg/ml Eye Drops, Suspension, compared to Placebo and Ketorolac Trometamol 5 mg/ml Eye Drops, Solution for the prevention and treatment of ocular inflammation and ocular pain…
- Trial name
- NCT00405730
- Testing
- Nepafenac 1mg/ml eye drops, suspension, Ketorolac Trometamol 5 mg/ml eye drops, solution, Nepafenac vehicle eye drops
- Where
- France
- Volunteers
- 227 people
- Sponsor
- Alcon Research
Post Menopausal Dry Eye Subjects
Efficacy of Systane Ultra in Post Menopausal Women With Dry Eye
To evaluate the efficacy of Systane Ultra in post menopausal women with dry eye.
- Trial name
- NCT01105910
- Testing
- Systane Ultra Lubricant Eye Drops, Sensitive Eyes Eye Drops (Bausch & Lomb)
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Contact Lens Related Dry Eye
Clinical Evaluation of the Causes of Contact Lens Related Dry Eye
The purpose of this study was to clinically evaluate the potential causes of contact lens-related dry eye.
- Trial name
- NCT00995189
- Testing
- Opti-Free RepleniSH, ReNu MultiPlus, Contact lenses
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Alcon Research
Contact Lenses
A Clinical Comparison of Three Contact Lens Care Systems and Their Effect on Contact Lenses
The purpose of this study was to evaluate the clinical performance of three differing contact lens care solutions when used in conjunction with three contact lenses.
- Trial name
- NCT00982046
- Testing
- Opti-Free RepleniSH multi-purpose disinfecting solution, ReNu MultiPlus multi-purpose solution, Clear Care cleaning and disinfecting system
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Alcon Research
Contact Lenses
Subjective and Conjunctival Response to Edge Design of Different Silicone Hydrogels
The purpose of this study was to evaluate the effect of different contact lens edge designs on the circumlimbal conjunctiva.
- Trial name
- NCT00940459
- Testing
- Senofilcon A contact lens (Acuvue Oasys), Comfilcon A contact lens (Biofinity), Lotrafilcon B contact lens (Air Optix)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Vitreomacular Traction, Vitreomacular Adhesion
Assessment of Patients Treated With JETREA® for Vitreomacular Traction
The purpose of this study is to observe the anatomical and functional outcomes of ocriplasmin (JETREA®) over a 6-month follow-up period.
- Trial name
- NCT02035748
- Testing
- Ocriplasmin
- Volunteers
- 628 people
- Sponsor
- Alcon Research