Clinical trials: sponsored by Alexandria University
Placenta Accreta Spectrum
Placenta Accreta Spectrum Outcome After Uterine Conservation
study will be carried out on patients with placenta accreta spectrum having done uterine conservation and recording immediate outcome of conservation regarding success of the procedure, amount of blood loss and amount of blood…
- Trial name
- PAS (NCT04866888)
- Testing
- closure of the uterine wall defect, ultrasound, outpatient hysteroscopy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Hyperkalemia
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
- Trial name
- NCT06029179
- Testing
- sodium zirconium cyclosilicate (SZC), sodium polystyrene sulfonate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection, Gastritis
7 Days vs. 14 Days of Vonoprazan-based Triple Therapy for H. Pylori Eradication
The study aims to test the efficacy of 7 days vs. 14 days of Vonoprazan-triple therapy in the eradication of Helicobacter Pylori infection in adolescents and young children.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Vonoprazan, Adolescents
- Trial name
- VOTE-HP (NCT06576882)
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 326 people
- Sponsor
- Alexandria University
Dialysis; Complications
Effect of Low Versus High Dialysate Sodium Concentration During Hemodialysis on Dialysis Recovery Time
This research aims to assess the effect of low versus high dialysate sodium concentration during hemodialysis on dialysis recovery time
- Trial name
- NCT05418647
- Testing
- high dialysate Na, low dialysate Na
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Breast Cancer
The Effect of Oral Administration of Hesperidin and Diosmin in Reducing Paclitaxel-induced Peripheral Neuropathy in Breast Cancer Patients
The aim of this study is evaluation of the potential neuroprotective effect of oral hesperidin and diosmin in reducing paclitaxel- induced peripheral neuropathy in the treatment of breast cancer patients.
- Trial name
- NCT06811220
- Testing
- Hespiridin and Diosmin
- Volunteers
- 140 people
- Sponsor
- Alexandria University
Preterm
Hemodynamic Response to Pain During Retinopathy Of Prematurity Screening
Study of cerebral hemodynamic changes in preterm infant and the effect of topical anesthetic eye drops ( benoxinate hydrochloride 0.4% ) on PIPP score and cerebral hemodynamic changes during fundus examination in neonates with…
- Trial name
- NCT05666362
- Testing
- benoxinate hydrochloride 0.4% group, saline 0.9% .
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Alexandria University
Preterm, Ventilator Lung; Newborn
Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound
This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates <37 gestational week with moderate to severe RD using…
- Trial name
- NCT06550219
- Testing
- Nasal humidified heated high flow cannula (NHHHC), Nasal intermittent positive pressure ventilation (NIPPV), Nasal continuous positive airway pressure NCPAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Burnout, Resilience
The Relationship Between Academic Burnout and Psychological Resilience
A cross sectional study of prevalence and correlates of burnout and resilience among indergraduate medical students
- Conditions
- Burnout, Resilience, Coping
- Trial name
- NCT06806215
- Where
- Egypt
- Volunteers
- 471 people
- Sponsor
- Alexandria University
Tear Trough Eyelid Deformity, Dark Eyelids
Periocular Rejuvenation by Topical Hyaluronic Acid Nano Particles
In this study, The investigators aims to evaluate the efficacy and safety of topical hyaluronic acid nanoparticles as a novel nanodermatological tool in periocular rejuvenation as a replacement approach of invasive dermal filler…
- Conditions
- Tear Trough Eyelid Deformity, Dark Eyelids, Wrinkle
- Trial name
- NCT05742399
- Testing
- Hyaluronic acid NanoGel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Molar Incisor Hypomineralization
EVALUATION of PREVENTIVE EFFECT of SEALANTS and LASER THERAPY on DENTAL CARIES and POSTERUPTIVE BREAKDOWN on MOLARS AFFECTED with MOLAR INCISOR HYPOMINERALISATION (RANDOMIZED CLINICAL TRIAL)
Background: Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrical involvement of one to four permanent first molars (PFM) with or without incisor teeth involvement.
- Trial name
- NCT06801561
- Testing
- Laser therapy, Glass ionomer sealant
- Where
- Egypt
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Molar Incisor Hypomineralization, Hypersensitivity
The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation
The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.
- Trial name
- NCT06348849
- Testing
- Low-level laser therapy, Nanosilver fluoride
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Female Infertility
Addition of Gonadotropin Releasing Hormone Agonist to Luteal Phase Support
Hormonal milieu during implantation is crucial to embryo-endometrium interaction and to the viability of the conceptus. Alterations in the peri-implantation environment are considered to impair perinatal outcomes in…
- Trial name
- NCT05286554
- Testing
- gonadotropin releasing hormone-agonist, Progesterone
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Alexandria University
Binge Eating Disorder
Dialectical Behavioral Therapy As A Therapeutic Tool In Patients With Binge Eating Disorder
Binge eating disorder (BED) is one of the recently acknowledged eating disorders, with many theories underlying its pathology whether biological or psychological.
- Trial name
- NCT05560529
- Testing
- DBT, TAU, Plasma Ghrelin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Adverse Effects of Endotracheal Intubation
Clinical Outcome of Endotracheal Intubation in Non-trauma Patients
The study will involve all adult patients visiting the Alexandria University main hospitals' Emergency department for reasons other than trauma that will require assisted ventilation via endotracheal intubation.
- Trial name
- NCT05795231
- Testing
- Macintosh Laryngoscope Vs Video Laryngoscope
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
White Spot Lesion
Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth
the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode.
- Trial name
- NCT06566833
- Testing
- self assmbling peptide p11-4 combined with 0.05% fluoride, Casein phosphopeptide amorphous calcium phosphate, 5% sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Septic Shock, Ventilator Acquired Pneumonia
Intravenous Metoprolol in Septic Shock
A RCT designed to assess the effect of giving intravenous beta-blockers in patients with septic shock after achieving hemodynamic stability.
- Trial name
- NCT06592547
- Testing
- Intravenous metoprolol tartrate, Standard Care (in control arm)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Spine Condition
Evaluating MIONM Effectiveness in Predicting Postoperative Neurological Deficits Using Combined Modalities
Objective: This study aimed to integrate findings from spinal and cranial surgeries with existing literature, emphasizing the role of Intraoperative Neurophysiological Monitoring (IONM) in improving surgical outcomes through best…
- Trial name
- MIONM (NCT06712069)
- Testing
- Multimodal Intraoperative Neurophysiologic Monitoring (MIONM)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Trigeminal Neuralgia, Refractory Pain
Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
- Trial name
- NCT06779578
- Testing
- Bipolar pulsed radiofrequency, Mopolar pulsed radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Insomnia, COVID - 19
A Prospective Study: Tai-chi and Post-COVID Insomnia
The goal of this study is to see if Tai-Chi exercises (a type of Chinese martial arts) can help people suffering from insomnia after COVID-19 when added with cognitive-behavioral therapy (CBT) and drugs compared to CBT and drugs…
- Trial name
- insomnia (NCT06776276)
- Testing
- Tai Chi exercises
- Where
- Egypt
- Volunteers
- 337 people
- Sponsor
- Alexandria University
Pregnant Women
Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section
The goal of this clinical trial is to assess the effect of IV pethidine and intrathecal pethidine on the incidence, onset, duration, and intensity of shivering in females undergoing caesarean section.
- Trial name
- NCT06775431
- Testing
- Pethidine Hydrochloride 50 Mg/mL Solution for Injection, Pethidine Hydrochloride 50 Mg/mL Solution for Injection administered intrathecally
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Alexandria University