Clinical trials: sponsored by Alexandria University
End Stage Renal Disease, Hypertension, Renal
Efficacy of L-methylfolate and Methylcobalamine in Treating Resistant Hypertension Associated With Elevated Serum Homocysteine in Hemodialysis Patients.
The aim of the study is to evaluate the efficacy of L-methylfolate in combination with methylcobalamine in reducing homocysteine blood levels in hypertensive end-stage renal disease patients on regular hemodialysis and its…
- Trial name
- NCT05807711
- Testing
- L-Methyl Folate and methylcobalamine
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Alexandria University
Mandibular Resection
A Novel Alloplastic Patient Specific Temporalis Tendon Enthesis
Mandibular reconstruction of segmental defects is an arduous surgical procedure that requires an utmost degree of surgical fidelity.
- Trial name
- NCT06770868
- Testing
- Patient specific reconstruction plate for patients suffering from mandibular segmental defects
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Alexandria University
Undergraduate Health Professional Students
Reflective Mindfulness and Emotional Regulation Training to Enhance Nursing Students' Self-Awareness, Understanding, and Regulation
This study assessed the impact of a six-week Reflective Mindfulness and Emotional Regulation Training (RMERT) program on fourth-year nursing students.
- Trial name
- NCT06760962
- Testing
- Reflective Mindfulness and Emotional Regulation training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Clinical Pharmacists, Electronic Medical Record
Relationship Between the Clinical Pharmacist & Antibiotic Use by Using the Electronic Program
A retrospective cohort study to explore the association between clinical pharmacists' interventions and antibiotic consumption through the use of the medical electronic reports and to identify mortality and cost savings in…
- Trial name
- NCT05002647
- Testing
- NO intervention
- Where
- Egypt
- Volunteers
- 2,601 people
- Sponsor
- Alexandria University
Oral Health Literacy, Oral Hygiene
Mobile Oral Health Intervention Effectiveness on Orthodontic Patients' Oral Hygiene and Oral Health Literacy
Orthodontic patients face unique challenges in maintaining optimal oral hygiene due to the presence of fixed orthodontic appliances, which tend to increase plaque retention, leading to gingival inflammation.
- Trial name
- NCT06734325
- Testing
- Mobile Oral Health Intervention
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anterior Mandibular Fracture
InterFlex Plate Versus Conventional Miniplates in the Management of Anterior Mandibular Fractures.
the study aims to compare InterFlex plate with conventional miniplates in management of symphyseal mandibular fracture clinically regarding pain, wound healing and postoperative occlusion, and radiographically regrading bone…
- Trial name
- InterFlex (NCT06740292)
- Testing
- conventional miniplates, InterFlex plates
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Alexandria University
Separation Anxiety
Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication
To study and compare the efficacy of intravenous formula of fentanyl citrate and midazolam administered orally for premedication in paediatric surgical patients.
- Trial name
- NCT05500599
- Testing
- Fentanyl Citrate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Chronic Pain Syndrome
Caudal Epidural Prolotherapy Versus Steroids in Failed Back Surgery Syndrome
This study will be held on patients with failed back surgery syndrome, the investigators are comparing prolotherapy and steroids injections in caudal epidural space to relieve the pain
- Trial name
- NCT05548738
- Testing
- medthylprednisolone, prolotherapy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Dental Occlusion, Occlusal Analysis
Trueness of Digital Occlusal Analysis
The aims of this observational study are to evaluate the trueness of two different digital occlusal analyzers; handheld occlusal analyzer versus intraoral scanner in comparison to conventional methods in identifying true occlusal…
- Trial name
- NCT06672627
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Scars
Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars
This study aims to evaluate the efficiency autologous nanofat injection versus autologous nanofat delivered by microneedling in management of post burn atrophic and traumatic scars.
- Trial name
- NCT06566300
- Testing
- injection of autologous nanofat grafting, microneedling with autologus nanofat graft
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Therapeutic Plasma Exchange
Comparison Between Centrifugation Based and Membrane Based Plasma Exchange
This study aims at comparing centrifugation based therapeutic plasma exchange (cTPE) versus membrane based therapeutic plasma exchange (mTPE) as regards performance, effectiveness and adverse events in patients indicated for TPE.
- Trial name
- NCT06652516
- Testing
- plasma exchange
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Acute Poisoning
Efficacy of SMOF Lipid in the Management of Acute Poisoning With Carbamazepine
The goal of the current study was to evaluate whether SMOF lipid administration could be used as an adjuvant therapy to treat acute, moderate-to-severe carbamazepine poisoning.
- Trial name
- NCT06316362
- Testing
- SMOF lipid 20%, Standard treatment for carbamazepine toxicity
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Leukemia, Children
Jacobson's Progressive Muscle Relaxation Technique on Children With Leukemia Undergoing Chemotherapy.
The goal of this clinical trial is to determine the effect of Jacobson's progressive muscle relaxation technique on anxiety and fatigue among children with leukemia undergoing chemotherapy.
- Conditions
- Leukemia, Children, Fatigue Related to Cancer Treatment, Anxiety
- Trial name
- JPMRT (NCT06631196)
- Testing
- Jacobson's PMRT
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pelvic Cancer, Abdominal Cancer
Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.
The investigators hypothesize that effect of addition of dexmedetomidine or ketamine by IV infusion to lidocaine infusion may be more beneficial than lidocaine infusion alone on proinflammatory cytokines (IL-1, IL-6 and TNFα)…
- Conditions
- Pelvic Cancer, Abdominal Cancer, Surgery, Proinflammatory Cytokines
- Trial name
- NCT06631625
- Testing
- Lidocaine Intravenous Infusion, Lidocaine and ketamine, lidocaine and dexmedetomidine infusion
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Athletes
Brain Wave Entrainment Using Alpha Frequency Binaural Beats on Adolescent Swimmers
Relaxation techniques and binaural beats added to music have a positive effect on athletic performance of swimmers than music therapy and mental training alone
- Trial name
- NCT06619470
- Testing
- binaural beats
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Impulsive Aggression, ADHD
Dialectical Behavioral Therapy Skills for Impulsive Aggression
This trial aims to Study the efficacy of DBT skills for impulsive aggression and executive dysfunctions in drug naïve children who are presented with impulsive aggression and ADHD and attending Child and adolescent clinic at…
- Conditions
- Impulsive Aggression, ADHD, Executive Dysfunction
- Trial name
- NCT05351944
- Testing
- Dialectical behavioral therapy skills for the intervention experimental group A, psychoeducation or Atomoxetine or stimulants according to ADHD severity
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Alexandria University
Hip Fracture, Antithrombotic Therapy
Assessing the Effectiveness and Safety of Pericapsular Nerve Group (PENG) Block in Hip Fracture Patients on Antithrombotic Therapy
PENG block will be done on patients with hip fracture either receiving antithrombotic therapy or not under ultrasound guidance
- Conditions
- Hip Fracture, Antithrombotic Therapy, PENG Block
- Trial name
- PENG Block (NCT06582667)
- Testing
- PENG block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Anxiety State, Efficacy, Self
Video-based Climate Change Program
Climate change represents a global crisis with far-reaching implications for health, including mental health. Among vulnerable populations, such as nursing students, climate change anxiety is emerging as a noteworthy concern.
- Trial name
- NCT06223412
- Testing
- video-based climate change program
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Portal Hypertension, Variceal Hemorrhage
Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer
Endoscopic variceal ligation (EVL) is used to control and prevent variceal bleeding in patients with liver cirrhosis, but it can be complicated by bleeding from post-EVL ulcers.
- Conditions
- Portal Hypertension, Variceal Hemorrhage, Ulcer Hemorrhage
- Trial name
- NCT05227833
- Testing
- Vonoprazan fumarate (Vonaspire), Pantoprazole 40mg
- Where
- Egypt
- Volunteers
- 284 people
- Sponsor
- Alexandria University