Clinical trials: sponsored by Alexandria University
Treatment Effectiveness
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
The trial tends to evaluate the efficacy of vonoprazan-based triple therapy in eradicating H. Pylori infection in adolescent patients in Egypt, in comparison to standard treatment regimens to determine if it offers superior…
- Trial name
- NCT06162949
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 242 people
- Sponsor
- Alexandria University
Inferior Alveolar Nerve Injuries
Orthodontic Extrusion of High Risk Impacted Mandibular Third Molar
The goal of this clinical trial is to investigate the usage of maxillary miniscrew and cross-arch elastics for the orthodontic traction of the impacted mandibular third molar in close proximity to the inferior alveolar nerve to…
- Trial name
- NCT06538688
- Testing
- Orthodontic extrusion of the impacted mandibular third molar by using the maxillary miniscrew and cross arch elastic power chain as a temporary anchorage device before extraction
- Where
- 3 sites in Egypt
- Volunteers
- 9 people
- Sponsor
- Alexandria University
Dialectical Behavior Therapy
Effect of Dialectical Behavior in Patients With Bipolar Disorder
This study aims to: Determine the effect of implementing Dialectical Behavior Therapy on emotion regulation difficulties, distress tolerance, and social functioning among patients with bipolar disorder.
- Trial name
- NCT05741268
- Testing
- Dialectical behavior therapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
ERAS, Lidocaine
Lidocaine Infusion With ERAS Protocol for Pancreatic Cancer Surgery: Effect on Pain and Patient Immunity.
The whole world now is directed to implement strategies that enhance the patient's quality of life and prevent tumor relapse. Enhanced recovery after pancreatic surgery (ERAPS) program was found to improve the quality of life as…
- Conditions
- ERAS, Lidocaine, Cancer of Pancreas, Natural Killer Cell Cytokine Production
- Trial name
- ERAS (NCT05470166)
- Testing
- Lidocaine IV, saline IV
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Maternal Care Patterns, Child Nutrition Disorders
Relationship Between Maternal Awareness About Vitamin D for Under- Five Years Children and Their Health Status Outcomes
The observational study aims to identify the relationship between maternal awareness about vitamin D for under-five-year-old children and their health status outcomes.
- Conditions
- Maternal Care Patterns, Child Nutrition Disorders, Vitamin D Deficiency
- Trial name
- Vit-D (NCT06562426)
- Testing
- Descriptive group on vitamin D awareness
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodialysis Complication
Auricular Acupressure and Fluid Restriction Program on Salivary Flow and Fluid Adherence in Children on Hemodialysis
This study aims to evaluate the effects of auricular acupressure on salivary flow rate and fluid restriction adherence among children undergoing Hemodialysis .
- Trial name
- NCT06562959
- Testing
- Fluid Restriction Program, Intervention Bundle (Fluid Restriction Program and Auricular Acupressure
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Chronic Kidney Diseases
Effect of Protein Restriction Plus EAA/KA Supplementation on GFR Decline in CKD
This study aims to investigate the effect of protein restriction plus KA/EAA supplementation on GFR decline in CKD patients.
- Trial name
- NCT05952544
- Testing
- essential amino acids and keto-analogues supplementation, low protein diet
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Alexandria University
Nutrition Disorder, Child, Neurologic Disorder
Whey-Based Partially Hydrolyzed Formula Versus Polymeric Formula On Undernourished Neurologically Impaired Children: Open-labelled Randomized Study
Purpose: Undernutrition is common in neurologically impaired children. It increases the burden of comorbidities and affects the quality of life of these children.
- Trial name
- NCT06356103
- Testing
- Whey-Based Partially Hydrolyzed Formula, received 50% of their caloric requirements as isocaloric polymeric formula (standard ) and 50% standard nutritional feeding according to ESPGHAN guidelines
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Septic Shock
Gender-based Differences in the Outcome of the Treatment of Persistent Septic Shock With Hydrocortisone
The aim of this study is to explore the gender-based differences in the outcomes of treatment with hydrocortisone in critically ill patients with persistent septic shock.
- Trial name
- NCT06537180
- Where
- Egypt
- Volunteers
- 621 people
- Sponsor
- Alexandria University
Knee Arthropathy, Anesthesia, Local
Modified TIPS Block for Total Knee Arthroplasty
The is carried out to compare triple injection peri-sartorial block to a modified block including an extra local anesthetic injection deep to the adductor longs muscle via a medial to lateral approach regarding the peri-operative…
- Trial name
- NCT06539910
- Testing
- General Anesthesia, TIPS block, Modified TIPS block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Sepsis
Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department
Aim of the study is to determine the diagnostic accuracy of point-of-care ultrasound and to determine its role in sepsis management .
- Trial name
- NCT05849194
- Testing
- POCUS examination
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Alexandria University
Temporomandibular Joint Disorders
Nd-YAG Laser Versus Epidermal Growth Factor For Myogenic Tempromandibular Disorder.
A clinical trial comparing the potential effect of 2 different modalities (Nd-YAG Laser Versus Epidermal growth factor injection) on pain reduction in patients suffering from myogenic tempromandibular disorder.
- Trial name
- NCT06044974
- Testing
- Nd-YAG Fotona, Epidermal Growth Factor
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cesarean Scar Defect
Comparative Study Between Hormonal and Hysteroscopic Management of Cesarean Scar Defect
Up to 70% of women who have had a previous caesarean section experience uterine niche, with 30% having symptoms. Prevalence rates vary between 24-70% using transvaginal ultrasonography and 56-84% using gel/saline instillation…
- Trial name
- NCT06529952
- Testing
- hysteroscopic surgery by resection and endocoagulation, hysteroscopic surgery by endocoagulation only, hormonal treatment
- Where
- 2 sites in Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hearing Impaired Children, Developmental Language Disorder
Rehabilitation of Narrative Language in Children With Hearing Impairment and Developmental Language Disorder
The importance of narrative skills is evident in their role in language development and their relation to important academic skills namely reading, comprehension, and writing.
- Trial name
- NCT05445687
- Testing
- Narrative language intervention program, Conventional language intervention
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Alexandria University
Nerve Block
The Efficacy and Safety of Landmark-guided Compared to Ultrasound-guided Erector Spinae Plane Block Techniques for Analgesia in Female Patients After Breast Surgery.
The erector spinae plane (ESP) block is a technique that helps alleviate acute pain. It involves injecting local anesthetic between the erector spinae muscle (ESM) and the vertebra's transverse process (TP).
- Trial name
- NCT06246292
- Testing
- Ultrasound-guided ESPB, Anatomical landmark-guided ESPB
- Where
- Egypt
- Volunteers
- 248 people
- Sponsor
- Alexandria University
Scars, Insulin
Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars.
- Trial name
- NCT06021275
- Testing
- Microneedling with topical application of regular insulin, Microneedling with topical application of saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Bullying
Bullying Experiences Among Alexandria Faculty of Medicine Students
A cross-sectional study was conducted at Faculty of Medicine, Alexandria to study the prevalence, types and consequences of bullying among medical students. An online survey was distributed among medical students.
- Trial name
- NCT06517329
- Where
- Egypt
- Volunteers
- 565 people
- Sponsor
- Alexandria University
Pleural Infection
Fluid Agitation Microbiologic Yield In Pleural Infection Feasibility Study
The goal of this study is to compare the microbiologic diagnostic yield of pre-aspiration agitated pleural fluid versus that of conventionally aspirated fluid in pleural infection patients.
- Trial name
- FLAG-PINS (NCT05702580)
- Testing
- Agitated Pleural Fluid Thoracentesis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
CS Scar Defect(Niche) How to Avoid
Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection
Anatomically Uterine niche is an iatrogenic pouch-like defect at the site of previous caesarean scar due to defective tissue healing.
- Trial name
- NCT06503627
- Testing
- bladder flap dissection
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodialysis Complication
Impact of Predialytic Oral Protein on Nutritional Status and Quality of Life in HD Patients
The aim of this work is to study the effects of oral protein-based supplements on nutritional status in hemodialysis patients
- Trial name
- NCT05952570
- Testing
- oral protein nutritional supplement (Fresubin protein powder), routine nutrition regimen
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University