Clinical trials: sponsored by Alexandria University
Coronary Artery Disease
The Power of Hand Reflexology in Ameliorating Anxiety, Pain, and Fatigue Among Patients Undergoing Coronary Angiography
Reflexology influences pain perception and pain-impulse transmission by releasing endorphins (12). Patients with a variety of medical illnesses can benefit from hand reflexology by lessening their physical and emotional…
- Trial name
- NCT05887362
- Testing
- Hand Reflexology
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Pacemaker DDD
The Feasibility of Motivational Interviewing on Emotional Intelligence, Dispositional Optimism, and Adherence to Care Practices Among Patients With Permanent Pacemaker
A cardiac pacemaker is an artificial apparatus that stimulates the myocardium electrically to depolarize, to begin a contraction when the heart's natural pacemaker does not work properly.
- Trial name
- NCT05883514
- Testing
- Motivational interviewing
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alexandria University
Self-affirmation, Back Massage
Effect of Self-affirmation Versus Back Massage on Psychological Distress and Fear of Birth Among Primigravid Women in Third Trimester
Based on the literature review, care must be emphasized on aspects of self-strengthening or self-affirmation to reduce stress and fear and equip women with the ability to manage stress and fear due to negative thoughts.
- Trial name
- NCT05883501
- Testing
- Self-affirmation versus back massage
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Mechanical Ventilation
Optimization of Serum Phosphorus Level and Weaning From Mechanical Ventilation
The goal of this clinical trial is to test the impact of serum phosphorus level optimization on weaning from mechanical ventilation in adult ICU patients in Alexandria University Hospitals.
- Trial name
- NCT05682846
- Testing
- Sodium glycerophosphate pentahydrate solution
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Alexandria University
Hypoxic Encephalopathy, Birth Asphyxia
Passive Cooling Versus Blanket-Roll III on The Myocardial Function of Asphyxiated Neonates
Studying the effect of passive versus Blanket roll III modality of therapeutic hypothermia (TH)on myocardial function of asphyxiated neonates through using tissue Doppler (TD).
- Conditions
- Hypoxic Encephalopathy, Birth Asphyxia, Neonatal Encephalopathy, Hypothermia, Newborn
- Trial name
- NCT05652738
- Testing
- Passive cooling application, cooling using Blanket roll III
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Anesthesia, Local
Cold Vibratory Stimuli on Pain Perception Governing Infiltration Anesthesia in in Children
Local anesthesia injections are sometimes painful, resulting in antagonistic cooperation, fear, and anxiety in children. This study aims to investigate the effectiveness of vibratory and cold stimulation before the injection to…
- Trial name
- NCT05857033
- Testing
- Buccal and direct palatal injection with the aid of Buzzy, Buccal and indirect palatal injection with the aid of Buzzy, Buccal and direct palatal injection without Buzzy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Respiratory Failure, Weaning Failure
HVNI for Successful Weaning in Respiratory Failure
The goal of this randomized active-controlled study is to investigate the role of high velocity nasal insufflation (HVNI) in the immediate post-extubation period and compare it with non-invasive positive pressure ventilation…
- Trial name
- REVIVER (NCT05855213)
- Testing
- High Velocity Nasal Insufflation, Non-invasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Esmolol Adverse Reaction
Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
sixty patients, of both sexes, of ASA I or II planned for ambulatory laparoscopic cholecystectomy under general anaesthesia were engaged into 2 groups.
- Trial name
- NCT05850832
- Testing
- Esmolol, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Ovarian Cancer
VATS IN PATIENTS WITH ADVANCED OVARIAN MALIGNANCIES
Ovarian cancer is the seventh most common cancer and the fifth leading cause of death in women worldwide. About 70% of patients with epithelial ovarian cancer present with advanced disease which will require a combination of…
- Trial name
- NCT05840029
- Testing
- VIDEO-ASSISTED THORACOSCOPIC SURGERY
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Alexandria University
Substance Use Disorders, Substance Dependence
Correlation of Genetic Variations With Clinical Response in Substance Use Disorder
This research outcomes can be summarized as follows: 1. Pharmacogenomic analysis of Substance Use Disorder (SUD) and medications used for the treatment of SUD. 2.
- Trial name
- NCT05833399
- Testing
- Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Resilience-based Intervention, Emotional Regulation, Grit and Life Satisfaction
The Impact of a Resilience-based Intervention on Emotional Regulation, Grit and Life Satisfaction: A Comparative Study Between Egyptian and Saudi Nursing Students
Nursing students may be perceived as having a stable college experience because they have a relatively clear career goal and a higher employment rate than students in other majors, but they consistently report that their heavy…
- Trial name
- NCT05828316
- Testing
- Resilience-based intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Pleural Effusion
Diagnostic Yield of Agitated Exudative Non-infected Pleural Effusion
The goal of this study is to compare the diagnostic yield in terms of cellular content and biochemical characteristics of pre-aspiration agitated pleural fluid versus that of conventionally aspirated fluid in pleural infection…
- Trial name
- NCT05819294
- Testing
- Agitated Pleural Fluid Thoracentesis
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Alexandria University
Postural Kyphosis, Neck Pain
Comparison Between Effect of Posterior Cervical Weighting and Deep Cervical Flexion Exercise on Forward Head Posture
It has been reported that the head protrudes forward relative to the body from the sagittal plane associated with the anterior shifting of the line of gravity (LOG) relative to the base of support (BOS).
- Conditions
- Postural Kyphosis, Neck Pain, Deformity of Spine, Deformity
- Trial name
- FHP (NCT04796051)
- Testing
- Neck orthosis - with posterior cervical weight, Deep cervical flexors exercise
- Where
- Egypt
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Self- Efficacy
Effect of Cognitive Stimulating Interventions on Cognitive Self-Efficacy and Sense of Happiness Among Older Adults
The present study aims to determine the effect of cognitive stimulation interventions on cognitive self-efficacy and sense of happiness among older adults.
- Trial name
- NCT05802043
- Testing
- Cognitive Stimulating Interventions
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hepatocellular Carcinoma, Hepatitis C
HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial
Data regarding hepatocellular carcinoma (HCC) recurrence after directly acting antivirals (DAAs) given for hepatitis C virus treatment are contradictory.
- Conditions
- Hepatocellular Carcinoma, Hepatitis C, Neoplasm Recurrence, Treatment Complication
- Trial name
- RCT (NCT04653818)
- Testing
- Velpatasvir/Sofosbuvir
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University
Shoulder Pain
Ultrasound Guided Steroids Injection Versus PRP for Shoulder Pain Relief
Comparison between effects of ultrasound guided platelet rich plasma injection versus steroids injection for pain relief in cases of partial rotator cuff tears
- Trial name
- PRP (NCT05317624)
- Testing
- Platelet rich plasma, Methylprednisolone
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Gingival Enlargement
Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy
The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites
- Trial name
- NCT05787912
- Testing
- Photobiomodulation, Hyaluronic acid after photobiomodulation
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Stroke, Ischemic, Stroke, Acute
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar, Hemiparesis
- Trial name
- NCT04770363
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Genitourinary Syndrome of Menopause
Management of Cancer Therapy Related Vulvovaginal Atrophy
The goal of this clinical trial is to: 1. evaluate the efficacy of PRP injection and PRP injection mixed with non-cross-linked hyaluronic acid compared to the control group receiving standard therapy with topical non-cross-linked…
- Trial name
- NCT05782920
- Testing
- Platelet rich plasma, non cross-linked hyaluronic acid, topical HA gel
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Heart Failure With Reduced Ejection Fraction
Effect of Empagliflozin on NT-Pro Brain Natriuretic Peptide in Heart Failure Patients With Reduced Ejection Fraction
This study aims to evaluate the relationship between NT-proBNP and empagliflozin effects in patients with chronic heart failure with mildly reduced ejection fraction (HFmrEF 41-49%) and reduced ejection fraction (HFrEF ≤40%)…
- Trial name
- NCT05778084
- Testing
- Empagliflozin 10 MG
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University