Clinical trials: sponsored by Alexandria University
Cancer Breast, Chronic Pain Syndrome
Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy
Modified radical mastectomy may be associated with severe post-operative pain, leading to chronic pain syndrome which usually requires optimal perioperative pain management.
- Trial name
- NCT04429893
- Testing
- magnesium sulphate, bupivicaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Cardiac Septal Defects With Coarctation of the Aorta, Mitral Regurgitation
Comparison of Erector Spinae Block and Pecto-Intercostal Facial Block For Enhanced Recovery in Adult Cardiac Surgery
The current study is designed to compare the perioperative analgesic efficacy of Erector spinae plane block (ESPB) and Pecto-intercostal-fascial plane block (PIFB) in adults undergoing cardiac surgery via median sternotomy.
- Trial name
- NCT05475561
- Testing
- Ultrasound guided Pecto-intercostal- fascial plane block, Ultrasound guided erector spinae plane block, Bupivacain
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Malocclusion
Effectiveness of Two Skeletally Anchored Force Mechanics for Skeletal Class II Correction in Growing Patients
Patients with skeletal Class II malocclusion due to mandibular retrognathism will be recruited and randomly allocated to three equal groups.
- Trial name
- NCT04884022
- Testing
- Miniplates in mandibular symphysis & infrazygomatic, Miniplates in external oblique ridge & anterior maxillary region
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Alexandria University
Learning Disorders, Executive Dysfunction
Application of a Training Program for Executive Functions in a Sample of Egyptian Children With Learning Disorder
In recent years, significant progress has been made on ways to improve Executive Functions (EF) skills for school readiness involving direct EF training and classroom educational programs.
- Trial name
- NCT05476133
- Testing
- Executive functions training-elementary and Promoting executive function in in the classroom
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Type 2 Diabetes
Cognitive Protective Effect of Newer Antidiabetic Drugs
The proposed study aims to: 1. Explore the cognitive protective effects of SGLT2 inhibitors and DPP-4 inhibitors in patients attending diabetic clinics in Alexandria 2.
- Trial name
- NCT05347459
- Testing
- Dapagliflozin, Empagliflozin, Canagliflozin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Agitation
Music and Essential Oil in Agitation
The study aims to assess the effect of using music and essential oil on agitation in mechanically ventilated patients. Listening to classical relaxation music, and inhalation to bergamot oil will be used in this study.
- Trial name
- NCT04722614
- Testing
- Music, Essential oil, Control
- Where
- 2 sites in Egypt
- Volunteers
- 123 people
- Sponsor
- Alexandria University
Diabetes Mellitus, Type 2
Short Message Service for Type 2 Diabetes
Diabetes is a chronic disease where type 1 diabetes (T1D) is due to autoimmune ẞ-cell destruction, usually leading to absolute insulin deficiency, type 2 diabetes (T2D) is due to a progressive loss of ẞ-cell insulin secretion…
- Trial name
- SMS4T2D (NCT04236206)
- Testing
- Mobile Phone Short Message Service
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Anterior Openbite
The Use of Statically Determinate Force System in Closure of Anterior Open Bite in Adults.
The aim of the current study was to evaluate and quantify the cephalometric changes produced by maxillary and mandibular extrusion arches in closure of anterior open bite in non-growing patients.
- Trial name
- NCT04901221
- Testing
- Extrusion arch
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Alexandria University
Nurse-Patient Relations, Patient Satisfaction
A Nurse Caring Behavior Protocol on Postoperative Cardiac Patient Satisfaction
the study aimed to evaluate the impact of implementing a nurse caring behavior (NCB) protocol on postoperative cardiac patient satisfaction.
- Conditions
- Nurse-Patient Relations, Patient Satisfaction, Caring
- Trial name
- NCT05446844
- Testing
- A nurse caring behavior protocol, Routine nursing care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Catheter Complications, Ambulation Difficulty
Position Change and Back Massage Versus Early Ambulation on Post Transfemoral Coronary Angiography Complications
The study aimed to assess the effect of position change and back massage versus early ambulation on post transfemoral coronary angiography complications.
- Conditions
- Catheter Complications, Ambulation Difficulty, Bleeding, Back Pain
- Trial name
- NCT05446987
- Testing
- Position change and back massage, Early ambulation
- Where
- Egypt
- Volunteers
- 185 people
- Sponsor
- Alexandria University
Female Stress Incontinence
Hybrid Versus Synthetic TOT for Treatment of SUI
This prospective study is conducted on female patients presenting with SUI at Alexandria main university hospital. Patients with neurogenic voiding dysfunction, history of anti-incontinence surgery, urge-predominant MUI…
- Trial name
- NCT05448482
- Testing
- Transobturator tape
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Periodontal Pocket
Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser
1. Primary objective To measure the gingival crevicular levels of A.actinomycetemcomitans and P.gingivalis after intra-pocket application of diode laser in severe periodontitis (stage 3 grade C) patients. 2.
- Trial name
- NCT05222737
- Testing
- medency diode laser, spirazole forte
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Irreversible Pulpitis
Diode Laser Pulpotomy of Mature Permanent Molars With Irreversible Pulpitis
Thirty six patients are included in this study. For each patient, a pulpotomy procedure is performed.
- Trial name
- NCT05427851
- Testing
- pulpotomy, Diode laser - fonalaser
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Major Abdominal Surgery
Immunomodulatory Effects of Dexmedetomidine Infusion
Anesthetic management may affect both immunostimulatory and immunosuppressive mechanisms directly by modulating immune cell function or indirectly by attenuating the stress response, Thus, the choice of anesthetic technique may…
- Trial name
- NCT04923737
- Testing
- Dexmedetomidine, 0.9% sodium chloride
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Difficult Mask Ventilation, Difficult Intubation
Effectiveness of C-MAC Video-stylet Versus C-MAC D- Blade Video-laryngoscope for Tracheal Intubation
Videolaryngoscopy provides a better laryngeal view and do not need airway alignment for tracheal intubation.
- Trial name
- NCT04759300
- Testing
- C-MAC VS, C-MAC VL D -blade
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Infertility
COMPARING TWO PROTOCOLS FOR FINAL OOCYTE MATURATION IN POOR RESPONDERS UNDERGOING GnRH-ANTAGONIST ICSI CYCLES
Poor ovarian responders (POR) include a significant proportion of women referred for IVF treatments (ranging from 9 to 24 %), most of whom are in late reproductive age.
- Trial name
- NCT05397795
- Testing
- 10000 IU hCG (Choriomon5000 IU; IBSA), Triptorelin 0.2 mg (Decapeptyl 0.1 mg; Ferring)
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Cleft Lip Palate, Cleft Lip, Unilateral, Complete
Nasoalveolar Molding for Egyptian Cleft Lip Palate Infants
The cleft lip and palate (CLP) is the commonest craniofacial anomaly worldwide. Nasoalveolar molding (NAM) therapy has emerged in the management of CLP as an early presurgical intervention to provide symmetry to severely deformed…
- Trial name
- EgyCleft (NCT03029195)
- Testing
- Nasoalveolar molding therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Remember the Name of a Given Drug
Drug Name Identification an Ignored Patient's Problem That Needs a Solution
Each of the recruited patient was given 3 different placebo drugs with 3 different mad up names to be taken for one month with different regiments.
- Trial name
- NCT05343234
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Tracheostomy
Percutaneous Tracheostomy
Description of a technical modification of percutaneous tracheostomy that involves a safety method for confirming the intratracheal location of the needle at the time of puncture, with preventing serious complications such as…
- Trial name
- NCT05343442
- Testing
- Percutaneous tracheostomy
- Where
- Egypt
- Volunteers
- 386 people
- Sponsor
- Alexandria University