Clinical trials: sponsored by Alexandria University
Myocardial Ischaemia
Comparison of the Effect of Two Anaesthesia Methods in Preventing Perioperative Myocardial Infarcation in Patients With Cardiac Risk Undergoing Total Knee Arthroplasty
Comparison of the effect of two anaesthesia methods in preventing perioperative myocardial infarction in patients with cardiac risk undergoing total knee arthroplasty
- Trial name
- NCT05340946
- Testing
- general anaesthesia, spinal anaesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Hepatitis C
Occult HCV Infection After DAAD Treatment in Haemodialysis Patients
This research aims to evaluate the prevalence and predictors of Occult HCV among hemodialysis (HD) patients who achieved 24 weeks sustained virological response (SVR) after treatment with direct-acting antiviral agents (DAA) by…
- Trial name
- NCT04719338
- Testing
- presence of HCV RNA in peripheral blood mononuclear cells (PBMCs) .
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Arterial Stiffness
Atorvastatin Effects On Arterial Stiffness In Hemodialysis
This research aims to assess effects of atorvastatin on arterial stiffness in hemodialysis patients
- Trial name
- NCT04472637
- Testing
- Atorvastatin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Dialysis; Complications
Dialysis Recovery Time: Associated Factors and Its Relation to Quality of Life
This study aims to identify factors affecting dialysis recovery time and the relation between dialysis recovery time and quality of life in hemodialysis patients.
- Trial name
- NCT04727281
- Testing
- Quality of life assessment using the Kidney Disease Quality of Life 36 (KDQOL-36) short form and Malnutrition-Inflammation Score
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Alexandria University
COVID 19
Therapeutic Plasma Exchange in Resistant Cytokine Storm of COVID 19
This research is planned to illustrate the efficacy of Therapeutic Plasma Exchange (TPE) treatment in COVID-19 patients with resistant cytokine storm state.
- Trial name
- NCT04457349
- Testing
- Therapeutic Plasma Exchange (TPE)
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Alexandria University
Pain, Post Operative
Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients
The study will be designed to compare the analgesic effect of ultrasound-guided pectointercostal fascial plane block versus tansversus thoracic plane block in adult cardiac surgery.
- Trial name
- NCT05323305
- Testing
- ultrasound guided regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Analgesia, Breast Cancer
US Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation
Prospective interventional study
- Trial name
- NCT04796363
- Testing
- Erector Spinae Plane Block with Bubivacaine, Standard General Anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Diabetic Neuropathies
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
Background: Diabetes mellitus is commonly complicated by diabetic peripheral neuropathy. Due to common side effects and poor tolerance to medication, poor adherence to medication is common in diabetic peripheral neuropathy.
- Trial name
- NCT05296759
- Testing
- botulinum toxin A, Gabapentin, Duloxetine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Gastric Antral Vascular Ectasia
Efficacy of Narrow Band Spectrum Endoscopy for the Diagnosis of Gastric Antral Vascular Ectasia in Patients With Liver Cirrhosis
the study aims to evaluate the role of similar technology of Narrow Band Imaging VIST video intelligent staining technology in the diagnosis of Gastric Antral Vascular ectasia in cirrhotic patients
- Trial name
- NCT04388150
- Testing
- Upper gastrointestinal endoscopy and biopsy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Rectal Cancer
Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer
The National Comprehensive Cancer Network (NCCN) guidelines recommend trimodality treatment for patients with middle and low LARC with neoadjuvant chemoradiotherapy (NA-CRT), surgical resection with TME, plus additional…
- Trial name
- NCT05274945
- Testing
- Radiotherapy, consolidation chemotherapy, TME or APR
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Alexandria University
Renal Injury, Child, Only
Comparison Between Different Anaesthesia Techniques Protecting Renal Function in Children Undergoing Radicle Nephrectomy
Up to date, Renal Cell carcinomas (RCC) are one of the prevalent primary renal neoplasms affecting children \& surgical radical nephrectomy is the conventional standard of care, as the choice of non-surgical modalities like…
- Trial name
- NCT05271253
- Testing
- Dexmedetomidine, bupivacaine, normal Saline
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Alexandria University
Cardiogenic Shock, Volume Responsiveness
Volume Responsiveness By Ultrasound Of Carotid Blood Flow In Patients With Cardiogenic Shock
Resuscitation of critically ill patients has changed since the advent of goal directed therapy. Today, practitioners providing fluid resuscitation are attentive of the danger associated with volume depletion while being aware of…
- Conditions
- Cardiogenic Shock, Volume Responsiveness, Ultrasound
- Trial name
- NCT05271227
- Testing
- Transthoracic echocardiography and Carotid artery doppler (PHILIPS HD11 XE ultrasound device) before and after PLR test.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Anesthesia, Local, Nerve Pain
SEQ Block for Perioperative Analgesia in Acetabular Surgery
The study will evaluate ultrasound guided SEQ block: single puncture combined lumbar erector spinae plane block and paraspinous sagittal shift (PSSS) quadratus lumborum block when compared with conventional intravenous morphine…
- Conditions
- Anesthesia, Local, Nerve Pain, Pain, Postoperative, Acetabular Fracture
- Trial name
- NCT04688814
- Testing
- Single puncture combined lumbar erector spinae plane block and quadrates lumborum block, Morphine Sulfate
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Alexandria University
Muscle Disorder
Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms
To compare the effects of stretching exercises versus thermotherapy on RLS symptoms and sleep quality among pregnant women. Research hypotheses: Pregnant women who perform leg stretching exercises exhibit lower RLS symptoms…
- Trial name
- Exersize (NCT05261035)
- Testing
- stretching exercises, thermotherapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hyperbilirubinemia, Neonatal
Bundling Gentle Body Massage Along With Regular Position Change Under Phototherapy
This study aimed to investigate the effect of bundling gentle body massage along with regular position change on bilirubin level and clinical outcomes among full-term neonates with hyperbilirubinemia under phototherapy.
- Trial name
- NCT05260138
- Testing
- Gentle Body message, Routine NICU Care
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Lung Diseases, Interstitial Lung Disease
Effects of Exercise Training on Respiratory Performance in Patients With Fibrosing Interstitial Lung Diseases
The current study recruited patients with fibrosing interstitial lung diseases (f-ILD) whatever was the underlying pathology. The investigators aimed to compare the effects of aerobic exercises for lower limbs (LL) versus upper…
- Conditions
- Lung Diseases, Interstitial Lung Disease, Fibrosis Lung
- Trial name
- ET-fILD (NCT05227443)
- Testing
- Exercise aerobic training, Upper, lower and breathing (ULB) exercise
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection
Efficacy of Clarithromycin and Flouroquinolones Based Regimens in H.Pylori Eradication in Covid-19 Era
Era of COVID-19 and the related panic lead to widely spread antibiotics misuse especially for azithromycin. Cross sensitivity between azithromycin and clarithromycin can impact success rates of H.
- Trial name
- NCT05035186
- Testing
- Amoxicillin
- Where
- Egypt
- Volunteers
- 233 people
- Sponsor
- Alexandria University
Female Infertility
Effect of Estradiol Pretreatment on Antagonist ICSI Cycles
Depended on the hypothesis that growth asynchrony of antral follicles is a consequence of the gradual follicle stimulating hormone (FSH) elevation that occurs during the late luteal phase, the aim of this work is to study the…
- Trial name
- NCT05197374
- Testing
- Estradiol Valerate 4mg
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Alexandria University
Mild-to-moderate COVID-19
Clinical Trial for Oral Formula of Vanillin and Wheat Germ Oil for Treatment of Mild and Moderate COVID-19 Viral Disease
The study is a randomized clinical trial to assess a natural formula of vanillin \& wheat germ oil to treat and stop the clinical progression of COVID-19.
- Trial name
- NCT05157139
- Testing
- Oral Capsule
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University