Clinical trials: sponsored by Alexandria University
Congenital Cataract, Microphthalmos
Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction
Early cataract surgery in microcornea/microphthalmia eyes is essential to prevent amblyopia and improve visual outcomes, including stereopsis.
- Conditions
- Congenital Cataract, Microphthalmos, Microcornea
- Trial name
- NCT04759560
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Alexandria University
Psychological Stress, Hemostatic Disorder
Copeptin and Psychological Stress of Medic During COVID-19 Pandemic
Psychological stress (PSS) is one of the most common problems among healthcare providers during COVID-19 pandemic. PSS influences the homeostatic equilibrium of the body, involving activation of the sympathetic nervous system and…
- Trial name
- COVID-19 (NCT04757285)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hypertension, Renal
Effect of Amlodipine Versus Bisoprolol on Hypertensive Patients With End-stage Renal Disease on Maintenance Hemodialysis.
Hypertension is highly prevalent in hemodialysis (HD) patients and leads to increased morbidity and mortality due to cardiovascular disease(CVD).
- Trial name
- NCT04085562
- Testing
- Bisoprolol Fumarate 5-10 mg, Amlodipine 5-10 mg
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Alexandria University
Single Lung Ventilation, Thoracic Anesthesia
C-MAC Video-stylet for Double- Lumen Tracheal Intubation
C-MAC Video Stylet secures the airway. It is a completely new type of video endoscope, it combines the advantages of both rigid and flexible intubation endoscopes.
- Trial name
- NCT04757558
- Testing
- C-MAC video-stylet, Macintosh laryngoscope
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Hypertrophic Scarring
Clinical Evaluation of the Efficacy OF Botulinum Toxin A for Improving Facial Scars
Background: Scars widen when the overlying musculature pulls apart suture lines. Because Botulinum Toxin A (BTA) is known to prevent fibroblast proliferation and it also induces temporary muscle paralysis, the purpose of this…
- Trial name
- NCT04756882
- Testing
- AbobotulinumtoxinA 500 UNT
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Rectum Cancer
MRI Split Scar Sign as a Predictor to Complete Pathologic Response After Neoadjuvant Chemoradiation in Rectal Cancer
Patients with middle or low rectal cancer who receive neoadjuvant chemoradiation and achieve complete clinical response while their pelvic MRI have split scar sign are included.
- Trial name
- NCT04745091
- Testing
- total mesorectal excision
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Duct Ectasia Breast, Benign Breast Disease
Central Mammary Duct Excision; How to Improve the Outcome?
the study compares two surgical techniques in excision of the central duct system of the breast. known also as major duct excision
- Trial name
- MDE (NCT04744766)
- Testing
- major duct excision
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Alexandria University
Sepsis Following A Procedure, Diagnoses, Syndromes, and Conditions
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1
The aim of the present work is to study: Persepsin (sCD-14) and Syndecan-1 as biomarkers following major surgeries for early diagnosis and prognosis of sepsis Primary aim: early diagnosis and prognosis of sepsis Secondary aim…
- Trial name
- NCT04718623
- Testing
- Quantitative determination of serum Presepsin (sCD-14), and Syndecan-1 concentrations
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Aphasia Rehabilitation
Post Stroke Aphasia Rehabilitation Using Computer-based Arabic Software Program: A Randomized Control Trial
Aphasia is a disorder of language processing caused by a lesion in particular brain regions. Treatment aims at improving or restoring impaired function or at compensating for deficits.
- Trial name
- aphasia (NCT04717180)
- Testing
- aphasia rehabilitation using software program or conventional therapy
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Alexandria University
Vitiligo
Punch Minigraft Versus Transverse Needling or Combination of Both in Treatment of Non-Segmental Vitiligo
This study is to evaluate the effectiveness and tolerability of autologous punch minigraft, transverse needling technique or combination of both followed by narrow band ultraviolet B phototherapy (311 nm) in the treatment of…
- Trial name
- NCT03872804
- Testing
- Autologous punch mini grafts:, Transverse needling, Punch minigrafts followed by transverse needling
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Dry Eye
Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study
Since the initial description, the therapeutic efficacy of CsA for human KCS has been well documented, with evidence ranging from several small single center randomized double-masked clinical trials to several large multicenter…
- Trial name
- NCT04714099
- Testing
- Topical Cyclosporine A
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Inflammatory Bowel Diseases, Helicobacter Pylori Infection
The Relationship Between Helicobacter Pylori Infection and Inflammatory Bowel Diseases: A Real-life Observation
Numerous epidemiological studies have investigated the association between Helicobacter pylori (H. pylori) infection and inflammatory bowel disease (IBD) with various conflicting results.
- Trial name
- NCT04708405
- Testing
- Observation
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodialysis Complication, ESRD
Individualized Incremental Hemodialysis Study
Thrice weekly hemodialysis has been the standard of care all-over the world for end-stage renal disease (ESRD) requiring renal replacement therapy (RRT).
- Conditions
- Hemodialysis Complication, ESRD, Renal Failure
- Trial name
- IIHD (NCT03352271)
- Testing
- Individualized Incremental hemodialysis, Conventional thrice weekly hemodialysis
- Where
- 2 sites in Egypt
- Volunteers
- 122 people
- Sponsor
- Alexandria University
Periodontitis
Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients.
Using local delivery drugs as adjunctive to scaling and root planing and evaluating gingival crevicular fluid (GCF) biological molecular markers (MMP-8).
- Trial name
- MMP-8 (NCT04605289)
- Testing
- lemongrass essential oil gel, Scaling and root planing
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Pleural Effusion
Modified Thoracoscopic Pleural Cryobiopsy in Diagnosis of Exudative Pleural Effusion
Background: Rigid thoracoscopy is the gold standard tool for diagnosing exudative pleural effusion but sometimes it is difficult to obtain sufficient biopsies using the conventional forceps.
- Trial name
- NCT04683419
- Testing
- Modified Thoracoscopic pleural Cryobiopsy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Hepatitis C, Relapse
Safety and Efficacy of Different Antiviral Regimens for Hepatitis C Virus Relapse
The primary goal of hepatitis C virus (HCV) Direct Acting Antivirals (DAAs) is to achieve undetectable HCV RNA in the blood. A response that should be maintained for at least 12 weeks from completion of therapy.
- Conditions
- Hepatitis C, Relapse, Antivirals
- Trial name
- NCT04662138
- Testing
- directly acting antivirals
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Alopecia Areata
Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma Using Either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata
The aim of this study is to evaluate the use of fractional carbon dioxide laser versus microneedling in the transepidermal delivery of triamcinolone acetonide and platelet rich plasma in treatment of alopecia areata.
- Trial name
- NCT04147845
- Testing
- Fractional Carbon Dioxide Laser, Microneedling using dermapen, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Marginal Adaptation of Fixed Dental Prosthesis
Accuracy and Reproducibility of Virtually Guided Minimally Invasive Tooth Preparations Using Reverse Engineering
The aim of the study is to assess and reproduce standardized virtually guided minimally invasive tooth preparations using digitally designed occlusal template, compared to its reference virtual preparation using a computer aided…
- Trial name
- NCT04653519
- Testing
- Virtually guided minimally invasive preparation
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Alexandria University
Necrotic Pulp, Periapical; Infection
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
- Trial name
- NCT04646538
- Testing
- Regenerative Endodontics Procedures (REPs)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Breast Cancer
Assessment of Nipple Sparing Mastectomy as a Treatment Option for Breast Cancer
Nipple-sparing mastectomy (NSM) with immediate breast reconstruction (IBR) is a form of mastectomy that achieves optimal disease control and facilitates reconstruction.
- Trial name
- NCT04640454
- Testing
- nipple sparing mastectomy
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Alexandria University