Clinical trials: sponsored by Alexandria University
Parent-Child Relations, Dental Fear
Parental Presence and Preschoolers' Behavior
Purpose: This study aimed to assess the effect of parental active/passive presence technique (PAP/PPP) on the overall behavior of preschool children with different intelligence and fear levels.
- Trial name
- NCT04580316
- Testing
- Parental active presence, Parent passive presence
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Sugammadex
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
The primary aim of the work is to compare the efficacy of Sugammadex and neostigmine in reversing rocuronium-induced muscle relaxation to reach complete recovery of neuromuscular block (TOF ratio≥ 0.9) in preterm neonates.
- Trial name
- NCT04566796
- Testing
- Sugammadex, Neostigmine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Nutritional Disorder
Evaluation of Micronutrients in Obese Patients
The aim of the study primarily was to investigate the value of zinc to copper ratio as possible biomarker of trace elements imbalance in morbidly obese subjects undergoing LSG.
- Trial name
- NCT04554082
- Testing
- laparoscopic sleeve gastrectomy
- Volunteers
- 107 people
- Sponsor
- Alexandria University
COVID 19
Efficacy and Safety of Sirolimus in COVID-19 Infection
This research is planned to illustrate the efficacy and safety of sirolimus as an adjuvant agent to the standard treatment protocol against COVID-19 infection
- Trial name
- NCT04461340
- Testing
- Sirolimus
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Chronic Obstructive Pulmonary Disease, Respiratory Failure
High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery
High-flow nasal cannula (HFNC) is a device that delivers10 to 70 L min-1 of heated, humidified 100% oxygen via nasal route. It provides positive airway pressure, decreases dyspnea, decreases the work of breathing, and improves…
- Trial name
- NCT04520568
- Testing
- High flow nasal cannula, CONTROL
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Chronic Polypous Rhinosinusitis
Effects of Lidocaine Infusion on Quality of Recovery and Agitation After Functional Endoscopic Sinus Surgery
The essential anesthesia requirements for FESS include airway management, considerations for facilitating surgical access, provision of a clear and still surgical field for precision surgery, assuring quick and non-stimulating…
- Trial name
- NCT04472689
- Testing
- Lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Hypoxic Brain Injury, Maternal Death
High Flow Nasal Cannula to Prevent Deoxygenation During Induction of General Anesthesia in Cesarean Section
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) using high flow oxygen therapy for preoxygenation and oxygen supplementation during apnoea has shown promising results
- Trial name
- NCT04438798
- Testing
- F Group, H Group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Pseudophakic Bullous Keratopathy, Anterior Chamber Intraocular Lens
Descemet Membrane Endothelial Keratoplasty Combined With Intraocular Lens Exchange: Sequential Versus Combined Surgery
Surgical treatment of corneal endothelial decompensation in the presence of an anterior chamber intraocular lens (AC IOL) is technically challenging.
- Trial name
- NCT04344522
- Testing
- Descemet membrane endothelial keratoplasty DMEK, IOL exchange, iridoplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Breast Cancer
Evaluating New Surgical Technique in Management of Female Patients With Operable Multifocal Breast Cancer
Multi-focal Breast Cancers(MFBC) still have undiscoverable Clinical Significance reflecting on a debatable surgical decision for this Category of breast cancer.
- Trial name
- NCT03900299
- Testing
- oncoplastic breast surgery
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Alexandria University
Immediate Implant
Immediate Implant Using Socket Shield Technique With Xenogenic Bone Graft
Adequate bone volume and a proper aesthetic outcome have become the main focus of interest in implant dentistry. Alveolar bone resorption is a natural course occurring after tooth removal.
- Trial name
- NCT04489654
- Testing
- deproteinized bovine bone mineral (DBBM) by OneXeno Graft. ( OneGraft, Germany)
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Gastrointestinal Stromal Tumor of Duodenum
Outcome After Surgical Resection of Gastrointestinal Stromal Tumors (GIST) in the Second Part of Duodenum
it is hypothesized that long term outcomes of localized resection of GIST tumors located in the second part of the duodenum are comparable to those of the traditional treatment by radical resection of the head o pancreas and the…
- Trial name
- GIST (NCT04487002)
- Testing
- surgical resection
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Alexandria University
Refractive Errors
Trifocal Diffractive Intraocular Lens After Cataract Extraction With Phacoemulsification
Multifocal IOLs that maintain distance focus and improve near vision have been developed to reduce spectacle dependence.Multifocal IOLs improve patient performance of near-vision tasks, such as reading crafts, hobbies, and social…
- Trial name
- NCT04465279
- Testing
- Trifocal diffractive intraocular lens
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Shoulder Impingement Syndrome
Effectiveness of Lyophilized Growth Factors for Subacromial Impingement
The aim of this study is to evaluate the efficacy of ultrasound-guided injection of platelet-derived lyophilized growth factors in treatment of subacromial impingement.
- Trial name
- NCT04330027
- Testing
- Growth factors, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Insulin Resistance, Hepatitis C
Effect of Hepatitis C Clearance on Insulin Resistance
Chronic hepatitis C infection has been linked to insulin resistance, which is the essential component of metabolic syndrome and type 2 diabetes mellitus.
- Trial name
- NCT04457050
- Testing
- Sofosbuvir 400 milligram, Daclatasvir 60 milligram, Ribavirin 400 milligram
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Keratoconus
Endothelial Cell Loss After Penetrating Keratoplasty
This work aimed at the assessment of corneal endothelial cell loss after toric ICL implantation for correction of myopia and astigmatism after penetrating keratoplasty.
- Trial name
- NCT04457063
- Testing
- PKP
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Alexandria University
Glaucoma
Preservative-free Tafluprost Eye Drops in Newly Diagnosed Patients With Glaucoma
Glaucoma encompasses a collective group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells and their axons, resulting in cupping, a distinctive appearance of the optic disc, and a pattern of…
- Trial name
- NCT04455126
- Testing
- Preservative-free tafluprost eye drops
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Myopia
Analysis of I-Trace High Order Aberrations Induced by Wavefront Optimized Ablation Profiles
This work aims at the analysis of ocular aberrations induced by wave front optimized ablation profiles WFO using I-Trace aberrometer (Ray -Tracing)
- Trial name
- NCT04452448
- Testing
- LASIK
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection
Lactoferrin in Helicobacter Pylori Eradication Either With Standard Triple Therapy or Sequential Therapy
The investigators aim at evaluating the efficacy of bovine lactoferrin addition to H. Pylori eradication regimens. 400 randomly distributed participants will be assigned to one of four treatment regimens of H.
- Trial name
- NCT04445948
- Testing
- Esomeprazole 40 milligrams Oral Tablet, Amoxicillin 1000 milligrams tablets, Clarithromycin 500 milligrams Tablets
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Alexandria University
Bilateral Inguinal Hernia
Laparoscopic Versus Open Mesh Repair of Bilateral Primary Inguinal Hernia
The best approach for simultaneous repair of bilateral inguinal hernia is controversial. The aim of this study is to compare the outcomes after laparoscopic versus open mesh repair of bilateral primary inguinal hernia
- Trial name
- NCT04437784
- Testing
- Laparoscopic Trans-Abdominal Pre-Peritoneal, Open pre-peritoneal repair, Bilateral Lichtenstein repair
- Volunteers
- 180 people
- Sponsor
- Alexandria University
Leukemic Patients With Increased Intracranial Pressure, Optic Nerve Sheath Fenestration
The Role of Optic Nerve Sheath Fenestration in Leukemic Patients Having Increased Intracranial Pressure
Optic nerve sheath fenestration (ONSF) first described by De Wecker in 1872 for the treatment of neuroretinitis. Since then, optic nerve sheath fenestration has become well established procedure for treatment of papilledema in…
- Trial name
- NCT04431882
- Testing
- optic nerve sheath fenestration
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University