Clinical trials: sponsored by Almirall, S.A.
Healthy Volunteers
Phototoxicity Test of Dapsone Gel in Healthy Volunteers
This study will evaluate the potential of dapsone gel and its vehicle to cause a phototoxic reaction following irradiation of the skin under controlled conditions.
- Trial name
- NCT02108483
- Testing
- dapsone gel, dapsone gel vehicle
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Healthy Volunteers
Photoallergy Potential of Dapsone Gel in Healthy Volunteers
This study will evaluate the potential of dapsone gel and its vehicle to cause a photoallergic reaction after repeated application and irradiation to the skin of healthy volunteers under controlled conditions.
- Trial name
- NCT02117739
- Testing
- dapsone gel, dapsone gel vehicle
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Healthy Volunteers
Dermal Tolerability of Dapsone Gel in Healthy Volunteers
This study will determine the cumulative irritation potential and sensitization potential of dapsone gel and vehicle after repeat applications on the skin of healthy volunteers.
- Trial name
- NCT02117752
- Testing
- dapsone gel, dapsone gel vehicle, sodium lauryl sulfate
- Where
- United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Psoriasis
Study of the Effects of the Organism on Monomethyl Fumarate (MMF) After the Administration of LAS41008
The purpose of this study is to determine how the organism affects MMF (metabolite of dimethyl fumarate [DMF]) after single oral dose administration of LAS41008 120 mg gastroresistant tablet and Fumaderm® 120 mg gastro-resistant…
- Trial name
- LAS41008 (NCT02955693)
- Testing
- LAS41008 120 mg / Fumaderm® 120 mg
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Actinic Keratosis
Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic Keratoses
The main purpose of this vehicle-controlled study is to determine the efficacy and safety of a solution of Actikerall® (containing 5-fluorouracil 0.5% and salicylic acid 10.0%) in the field-directed treatment of grade I-II…
- Trial name
- NCT02289768
- Testing
- 5-fluorouracil/salicylic acid, Vehicle
- Where
- 14 sites in Germany, United Kingdom
- Volunteers
- 166 people
- Sponsor
- Almirall, S.A.
Plaque Psoriasis
LAS41008 in Moderate to Severe Chronic Plaque Psoriasis
The aim of the study is to evaluate the efficacy and safety of LAS41008 in comparison to active control and placebo in patients with moderate to severe chronic plaque psoriasis
- Trial name
- NCT01726933
- Testing
- LAS41008, LASW1835
- Where
- 4 sites in Austria, Germany and 2 more
- Volunteers
- 839 people
- Sponsor
- Almirall, S.A.
Actinic Keratosis
Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis
The purpose of this study is to investigate the efficacy of LAS41005 in comparison to placebo and to LAS106521 in actinic keratosis (AK).
- Trial name
- NCT00987246
- Testing
- LAS41005, LAS106521
- Where
- 40 sites in Germany
- Volunteers
- 470 people
- Sponsor
- Almirall, S.A.
Chronic Obstructive Pulmonary Disease (COPD)
Study Evaluating Preference, Satisfaction and Ease of Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Diagnosed Patients
Preference study: Genuair vs HandiHaler inhalers in COPD patients.
- Trial name
- NCT01385696
- Testing
- Genuair® (Almirall S.A.), HandiHaler® (Boehringer Ingelheim's)
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 130 people
- Sponsor
- Almirall, S.A.
Psoriasis
A Intra-individual Comparison to Investigate the Efficacy and the Safety of LAS41004 Formulation in Mild to Moderate Psoriasis
Proof-of concept study to competitively investigate antipsoriatic efficacy and safety of a LAS41004 formulation vs active control No formal study hypothesis, but descriptive evaluation (PoC).
- Trial name
- Left/Right (NCT02180464)
- Testing
- LAS41004, control
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Almirall, S.A.
Nail Psoriasis
Efficacy and Safety of Tazarotene Gel in Nail Psoriasis
The aim of this study is to determine the efficacy and safety of topical application of the gel compared to placebo in nail psoriasis.
- Trial name
- NCT02235480
- Testing
- Experimental Tazarotene Gel
- Where
- 4 sites in Germany
- Volunteers
- 66 people
- Sponsor
- Almirall, S.A.
Psoriasis
Exploratory Study to Investigate Efficacy of LAS41004 in a Psoriasis Plaque Test
The aim of the exploratory study is to compare the dose-related efficacy of LAS41004 in a Psoriasis Plaque Test (PPT).
- Trial name
- NCT01360944
- Testing
- LAS41004, reference
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Almirall, S.A.
Migraine
Standardized sTudy With Almotriptan in eaRly Treatment of Migraine
This is a observational, open, prospective, single arm cohort study within authorized SPC conditions to describe the effectiveness of Almotriptan in treating acute migraine attacks when pain is mild and in the first hour of pain…
- Trial name
- START (NCT00725140)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 501 people
- Sponsor
- Almirall, S.A.
Actinic Keratosis
Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis
The aim of this study is to determine the efficacy, safety and tolerability of either a once or twice daily topical application of LAS41007 compared to a twice daily application of LAS106521 in the treatment of actinic keratosis.
- Trial name
- NCT00991861
- Testing
- LAS41007 o.d., LAS41007 b.i.d., LAS106521
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Almirall, S.A.
Psoriasis
Study to Investigate Dose-related Efficacy of LAS41004 in the Treatment of Psoriasis
The aim of the study is to intra-individually compare the dose-related efficacy of LAS41004 in a Psoriasis Plaque Test (PPT)
- Trial name
- NCT01119339
- Testing
- LAS 41004, LAS 41004 dosage 6, Reference
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Almirall, S.A.
Psoriasis
Clinical Trial to Investigate Efficacy of LAS41004 in Psoriasis
The aim of the study is to intra-individually compare the dose-related efficacy of LAS41004 in a Psoriasis Plaque Test (PPT)
- Trial name
- NCT01283698
- Testing
- Experimental: LAS 41004 dosage 1, Experimental: LAS 41004 dosage 2, Experimental: LAS 41004 dosage 3
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Almirall, S.A.
Actinic Keratosis
LAS41005 in Hyperkeratotic Actinic Keratosis
The aim of this study is to evaluate the efficacy and safety of LAS 41005 compared to cryotherapy in subjects with moderate to severe hyperkeratotic actinic keratosis (punch biopsies).
- Trial name
- NCT01358851
- Testing
- Cryotherapy, LAS41005
- Where
- 4 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Almirall, S.A.
Chronic Obstructive Pulmonary Disease (COPD)
Preference, Satisfaction and Ease of Use of Genuair® (Pressair™) and Breezhaler® (Neohaler™) Inhalers in Patients With COPD
Preference study: Genuair® (Pressair™) vs Breezhaler® (Neohaler™) inhalers in patients with COPD
- Trial name
- NCT01915784
- Testing
- Genuair®, Breezhaler®
- Where
- 6 sites in Germany, Spain and 1 more
- Volunteers
- 128 people
- Sponsor
- Almirall, S.A.
Psoriasis
Efficacy, Tolerability and Safety of LAS41004 Formulations in a Psoriasis Plaque Test
Clinical investigation of anti-psoriatic efficacy and atrophy
- Trial name
- NCT02111499
- Testing
- LAS41004-IMP1, LAS41004 IMP2, LAS41004 IMP3
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Almirall, S.A.
Asthma
A Single-dose, Randomised, Crossover, Placebo-controlled Study Assessing Two Fixed-dose Combinations of Inhaled Long-acting Beta-agonist and Corticosteroid
The purpose of this study is to assess the the ability of a single dose of LAS40468 administered via Genuair® and a single dose of salmeterol/fluticasone propionate (Seretide®) administered via Accuhaler to produce…
- Trial name
- NCT02094274
- Testing
- LAS40468, Salmeterol/fluticasone propionate
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Almirall, S.A.
Multiple Sclerosis
Neurophysiological Study of Sativex in Multiple Sclerosis (MS) Spasticity
Aim of this randomized, double-blind, placebo-controlled, cross-over study is to investigate cannabinoid-induced changes in neurophysiological parameters in a group of 40 patients with secondary or primary progressive Multiple…
- Trial name
- NS-MSS (NCT01538225)
- Testing
- Sativex®
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Almirall, S.A.