Clinical trials: sponsored by Anhui Provincial Hospital
Prostate Cancer, PET/CT
Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [18F]AlF-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT06756334
- Testing
- [18F]AlF-PSMA-N5, [18F]F-DCFPyL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Platelet Recovery After Umbilical Cord Blood Transplantation
Avatrombopag for Platelet Recovery Post-UCBT in Patients With Bone Marrow Failure Disease
To evaluate the efficacy and safety of Avatrombopag for platelet recovery after unrelated cord blood transplantation (UCBT) in patients with bone marrow failure disease
- Trial name
- AVA (NCT05823376)
- Testing
- Avatrombopag
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Provincial Hospital
Toxicity, Drug
Neoadjuvant CRT Combined With Camrelizumab and Nimotuzumab for Initially Inoperable Patients With Esophageal Carcinoma
Neoadjuvant chemoradiotherapy followed by surgery has been the standard modality for locally advance esophageal carcinoma. According to CROSS study, the pathological complete remission rate achieved by paclitaxel and carboplatin…
- Trial name
- NCT05355168
- Testing
- neoadjuvant chemoradiotherapy combined with Camrelizumab and Nimotuzumab followed by surgery
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Anhui Provincial Hospital
High Titers of Anti-HLA Antibody (MFI ≥5000)
The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT
Evaluation of the efficacy and safety of immunoadsorption or plasma exchange combined with rituximab and high-dose IVIG to reduce high titres of anti-HLA antibodies in patients prior to allogeneic haematopoietic stem cell…
- Trial name
- NCT06362967
- Testing
- Immunoadsorption or plasma exchange combined with rituximab, high-dose IVIG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital
Hematopoietic Recovery
The Safety and Efficacy of Coenzyme I for Injection in Promoting Hematopoietic Recovery of Patients After sUCBT
To assess the safety and efficacy of coenzyme I for injection in promoting hematopoietic recovery after single-unit unrelated cord blood transplantation in hematological malignancies.
- Trial name
- NCT06558253
- Testing
- Coenzyme I for Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Anhui Provincial Hospital
Epithelial Ovarian Cancer, Sentinel Lymph Node Detection
The Application of Sentinel Lymph Node Mapping Technique in the Surgery of Early Epithelial Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to evaluate the feasibility, sensitivity, and specificity of sentinel lymph node (SLN) mapping technology in the population with early epithelial ovarian…
- Trial name
- NCT06673511
- Testing
- Lymph node visualization, No visualization of lymph nodes
- Volunteers
- 246 people
- Sponsor
- Anhui Provincial Hospital
Platelet Recovery After Umbilical Cord Blood Transplantation
Romiplostim N01 for Platelet Recovery in Adult Hematologic Malignancies Patients Undergoing UCBT
To evaluate the efficacy and safety of Romiplostim N01 for platelet recovery after umbilical cord blood transplantation (UCBT) in patients with hematological malignancies.
- Trial name
- NCT06693791
- Testing
- Romiplostim N01
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Anhui Provincial Hospital
Prostate Cancer
Pathological Positivity Rate in Prostate Cancer Patients with PI-RADS 4 and First Negative Biopsy
The purpose of this prospective, single-center, single-arm trial was to evaluate the pathologic type of re-treatment based on a clear PI-RADS score of ≥4 with a first negative prostate biopsy, belonging to the high-risk group of…
- Trial name
- NCT06677775
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital
Thrombocytopenia
Lusutrombopag Combined With Recombinant Human Thrombopoietin for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Destined to Undergo Elective Invasive Surgery
To assess the efficacy and safety of lusutrombopag combined with recombinant human thrombopoietin for the treatment of thrombocytopenia in patients with chronic liver disease destined to undergo elective invasive surgery.
- Trial name
- NCT06673498
- Testing
- Lusutrombopag combined with recombinant human thrombopoietin
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Anhui Provincial Hospital
Cirrhosis Liver
A Clinical Study to Evaluate CUD005 Injection in Patients with Liver Cirrhosis
A single-arm, open-label, dose-escalation phase I clinical trial to evaluate the safety, tolerability, and preliminary efficacy of CUD005 injection in patients with liver cirrhosis
- Trial name
- NCT06671275
- Testing
- Cell therapy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Anhui Provincial Hospital
Ovarian Cancer, Epithelial
Ultrasensitive SERS Platform With Highly Efficient Enrichment of Analyte for Screening and Diagnosis of Epithelial Ovarian Cancer
This project is an open, single-center, prospective study aimed at developing high-sensitivity, high-specificity enrichment SERS chips using femtosecond laser processing technology.
- Trial name
- NCT06640348
- Testing
- No intervention
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Small-cell Lung Cancer
Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung Cancer
Concurrent chemoradiotherapy has long been the standard modality for locally advanced small-cell lung cancer, which could achieve median overall survival of 25 mos.
- Trial name
- NCT06527898
- Testing
- hypofractionated radiotherapy with immunotherapy
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Anhui Provincial Hospital
Unresectable Hepatocellular Carcinoma
"cindilizumab + Bevacizumab + Coenzyme I for Injection" in Unresectable Hepatocellular Carcinoma
This study is a single-arm, single-center, non-randomized, open-label study. A total of 37 patients with locally advanced or metastatic HCC who have not received systemic therapy, are not suitable for radical surgical resection…
- Trial name
- NCT06590844
- Testing
- Injectable coenzyme I
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Anhui Provincial Hospital
Esophageal Squamous Cell Carcinoma
Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy
The goal of this study was to explore the efficacy and safety of neoadjuvant chemoimmunotherapy followed by surgery and postoperative radioimmunotherapy in patients with locally advanced esophageal squamous cell carcinoma
- Trial name
- NCT06602843
- Testing
- Neoadjuvant chemoimmunotherapy followed by surgery and postoperative radioimmunotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Anhui Provincial Hospital
Parkinson Disease
iDAP Injection in the Treatment of Parkinson's Disease
The goal of this clinical trial is to evaluate the safety, tolerability and preliminary efficacy that iDAP has on Parkinson's disease (PD) patients.
- Trial name
- NCT06583291
- Testing
- Allogeneic dopaminergic neural precursor cell(iDAP)
- Volunteers
- 12 people
- Sponsor
- Anhui Provincial Hospital
Safety Issues, Efficacy, Self
Hypofraction Radiotherapy for Limited-Stage Small Cell Lung Cancer
Concurrent chemoradiotherapy is the standard modality for locally advanced small-cell lung cancer, which could achieve median overall survival of 25 mos.
- Trial name
- NCT05523908
- Testing
- High-dose hypofraction Arm, Low-dose hypofraction Arm (Standard BED)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Provincial Hospital
Nutrition Disorders
Effect of Nutritional Intervention Based on Prediction Model on Adult Umbilical Cord Blood Transplantation Patients
Based on the nutritional factor prediction model, the individualized nutritional management of patients with umbilical cord blood transplantation (UCBT) was carried out to observe the impact on the survival efficacy of patients.
- Trial name
- NCT06553274
- Testing
- Individualized nutrition intervention
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Anhui Provincial Hospital
Extensive-stage Small Cell Lung Cancer
Radiotherapy to All Residual Lesions After Chemoimmunotherapy
Extensive-stage small-cell lung cancer is a lethal malignancy with an extremely poor prognosis. First-line chemotherapy could only achieve an overall survival of approximately 10 months.
- Trial name
- NCT06479473
- Testing
- Radiotherapy to all residual lesions, Chemoimmunotherapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Anhui Provincial Hospital
Epithelial Ovarian Cancer, Efficacy
Fluzoparib in Combination With Apatinib Mesylate for Maintenance Therapy in Stage III-IV Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to observe and evaluate the efficacy and safety of fluazoparib combined with apatinib mesylate in the treatment of patients with ovarian cancer.
- Conditions
- Epithelial Ovarian Cancer, Efficacy, Safety, Bone Mineral Density
- Trial name
- NCT06539091
- Testing
- Fluzoparib, Apatinib Mesylate
- Volunteers
- 51 people
- Sponsor
- Anhui Provincial Hospital
Fiberoptic Bronchoscopy
Comparison of Efficacy and Safety Between Ciprofol and Remimazolam During Fiberoptic Bronchoscopy
Both ciprofol and remimazolam have been found to be potential alternatives to propofol (a commonly used anesthesia) during fiberoptic bronchoscopy, while the efficacy and safety between ciprofol and remimazolam have not been…
- Trial name
- NCT06531915
- Testing
- Ciprofol, Remimazolam
- Volunteers
- 190 people
- Sponsor
- Anhui Provincial Hospital