Clinical trials: sponsored by Asan Medical Center
Pancreatic Cancer, Adult, Margin, Tumor-Free
Usefulness of the Artery First Approach in Pancreatic Cancer Surgery
This study is aimed to evaluate difference of the 2 year recurrence free survival after pancreaticoduodenectomy for pancreatic cancer between artery-first approach and conventional procedure groups.
- Conditions
- Pancreatic Cancer, Adult, Margin, Tumor-Free, Surgery Site Fistula, Recurrence Tumor
- Trial name
- NCT04136522
- Testing
- conventional pancreaticoduodenectomy, total mesopancreas excision including superior mesenteric artery first approach
- Where
- South Korea
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Lung Neoplasm Malignant
Beneficial Effect of Pulmonary Rehabilitation in Lung Cancer Patients Receiving Radiation Therapy
It is important for clinicians to maintain and support for exercise capacity and quality of life of lung cancer patients after radiation therapy, because radiation therapy also affect the lung function and general conditions of…
- Trial name
- NCT05414188
- Testing
- Pulmonary rehabilitation
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Asan Medical Center
Chronic Obstructive Pulmonary Disease
Efficacy of 8-week Supervision in Home Based Pulmonary Rehabilitation
In korea, it is not easy to practice standard pulmonary rehabilitation (PR). in this study, we'll educate PR to patients and make reservation for re-visiting outpatients clinics with PR diary.
- Trial name
- NCT03754881
- Testing
- Pulmonary rehabilitation
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Asan Medical Center
Pulmonary Rehabilitation, Cardiac Rehabilitation
Rehabilitation of Chronic Diseases and Smart Health Management System Service
In Republic of Korea, it is not easy to practice standard pulmonary rehabilitation (PR) or cardiac rehabilitation (CR). In this study, the investigators will provide newly developed smartphone application to patients with chronic…
- Trial name
- NCT05383950
- Testing
- smartphone application
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Pancreaticoduodenectomy, Delayed Gastric Emptying
Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition
Pylorus preserving pancreaticoduodenectomy has been standard procedure for periampullary benign and malignant disease. Delayed gastric emptying is one of most common complications after the procedure.
- Conditions
- Pancreaticoduodenectomy, Delayed Gastric Emptying, Nutrition
- Trial name
- NCT05314244
- Testing
- Pylorus resecting pancreaticoduodenectomy
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Cardiac Arrest, Metabolic Acidosis
Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.
- Trial name
- NCT02303548
- Testing
- Sodium bicarbonate, Normal saline
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Fluid Responsiveness, Modified Prone Position
Pleth Variability Index in Modified Prone Position or Knee-chest Position (Concord Position)
To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation.
- Trial name
- NCT04002193
- Testing
- volume expansion
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center
Hip Fractures, Regional Anesthesia
Comparison of PENG Block and FICB in Hip Fracture Patients
Fascia iliaca compartment block (FICB) has been considered the block of choice for patients with hip fracture. However, pericapsular nerve group (PENG) block, one of the relatively newly-developed blocks, could be also used for…
- Trial name
- NCT04677348
- Testing
- Pericapsular nerve group (PENG) block, Fascia iliaca compartment block (FICB)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Heart Decompensation, Mechanical Ventilation Pressure High
Comparison of PEEP in Acute Decompensated Heart Failure
Little is known about optimal level of positive end-expiratory pressure (PEEP) in patiens who recieved invasive mechanical ventilation for acute decompensated heart failure.
- Trial name
- NCT04853563
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Asan Medical Center
Endometrial Cancer
Randomized Comparison Between Sentinel Lymph Node Biopsy and Lymph Node Dissection in Early Stage Endometrial Cancer
Through this clinical trial, the investigators aim to verify the usefulness and stability of sentinel lymph node mapping in endometrial cancer of clinical stage I-II.
- Trial name
- SELYE (NCT04845828)
- Testing
- Sentinel lymph node mapping, Routine lymph node dissection
- Where
- South Korea
- Volunteers
- 810 people
- Sponsor
- Asan Medical Center
Stroke
Anti-platelet Precision Medicine to Prevent Stroke Early Progression and Recurrence (PRECISE)
This is a pragmatic, multi-center, non-interventional, non-randomized prospective observational study.
- Trial name
- NCT03701360
- Where
- South Korea
- Volunteers
- 1,199 people
- Sponsor
- Asan Medical Center
Cleft Palate
Effect of Neck Extension on Intraocular Pressure in Patients Undergoing Palatoplasty
The purpose of this study is to investigate the change in intraocular pressure according to the neck extension during palatoplasty in pediatric patients.
- Trial name
- NCT04683978
- Testing
- Position
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Asan Medical Center
Ulcerative Colitis
Prediction Model for Response to Biologics and Small Molecular Agent for UC
This prospective observational study is going to develop and validate a prediction model of response to biologic agents and small molecular agents for Korean patients with ulcerative colitis.
- Trial name
- NCT05186623
- Testing
- Vedolizumab, Ustekinumab, or Tofacitinib
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Embolic Stroke of Undetermined Source
Prospective Registry of Elderly ESUS With PFO
Patent foramen ovale (PFO) is associated with an increased risk of stroke. PFO-closure was effective in preventing stroke in young stroke patients less than age 60 presented as an embolic stroke of undetermined source (ESUS).
- Trial name
- COACH_ESUS (NCT05238610)
- Testing
- PFO closure
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Asan Medical Center
Prostatic Neoplasms
Impact of Adjuvant Statin Therapy in Patients Who Underwent Radical Prostatectomy for Locally Advanced Prostate Cancer
Biochemical recurrence develops in approximately 30-40% of men with locally advanced prostate cancer who undergo radical prostatectomy.
- Trial name
- NCT01759836
- Testing
- Atorvastatin 20mg
- Where
- South Korea
- Volunteers
- 364 people
- Sponsor
- Asan Medical Center
Dysphagia of Newborn
Development of Dysphagia Evaluation Via Video Analysis Based on Deep Learning Method in Neonates and Infants and Correlation Between the Evaluation and the Development
The purpose of this study is to develop an evaluation of dysphagia through deep learning-based video analysis in newborns and infants, and to report the correlation with future development.
- Trial name
- NCT05204966
- Testing
- AI analysis
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Severe Asthma
Precision Medicine Intervention in Severe Asthma (PRISM) Study
The Korea-UK Precision Medicine Intervention in Severe Asthma (PRISM) study aims to identify molecular phenotypes of severe asthma by analyzing multi-omics data including genomics, epigenomics, transcriptomics, proteomics…
- Trial name
- NCT05164939
- Where
- 2 sites in South Korea, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Tuberculosis
Development of a Rapid and Accurate Diagnostic Assay for Tuberculosis
This study evaluates new technique for diagnosis of tuberculosis. Among patients who are suspected with tuberculosis, participants will be tested conventional method including Xpert TB/RIF assay, and new diagnostic technique…
- Trial name
- NCT03423550
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Patients With Suspected or Diagnosed Central Nervous System Lymphoma
Prospective Comparison of 18F-FDG and 18F-FET PET for Response Evaluation in Patients With Primary Central Nervous System Lymphoma
The overall goal of this imaging trial is to prospectively compare the usefulness of 18F-FDG PET and 18F-FET PET in evaluating treatment response and predicting prognosis in patients with central nervous system lymphoma.
- Trial name
- NCT05083936
- Testing
- [18F]FET
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center